Objective: To develop and evaluate a Dual-modality Complementary Feature Attention Network (DCFAN) that integrates spatial and stiffness information from B-mode ultrasound and shear wave elastography (SWE) for improved breast tumor classification and axillary lymph node (ALN) metastasis prediction.
Methods: A total of 387 paired B-mode and SWE images from 218 patients were retrospectively analyzed. The proposed DCFAN incorporates attention mechanisms to effectively fuse structural features from B-mode ultrasound with stiffness features from SWE.
J Colloid Interface Sci
December 2025
For the self-healing polymer, the recovery of mechanical properties and self-healing mechanisms are significantly affected by the time and temperature dependences of physical and chemical bonding dynamics, or by a synergistic combination of the two. In this work, the self-healing dynamics of chains consisting of short polydimethylsiloxane (PDMS) blocks joined together at their ends through both hydrogen-bond-forming ureido and dynamic imine linkages are systematically investigated by shear and extensional rheology, in situ Fourier transfer infrared spectra (FTIR), and self-healing time of severed samples. Using synthesized polymers with different ratios of ureido and imine linkages and measuring rheology and dynamics of the self-healing process over a range of temperatures, it is shown that the self-healing time is comparable to characteristic relaxation time (the inverse of the cross-over frequency of G' and G″ near the terminal zone).
View Article and Find Full Text PDFBackground: This study aims to evaluate the efficacy of a three-dimensional visualization operative planning system (3DVOPS) in ultrasound-guided percutaneous microwave ablation (US-PMWA) for the treatment of large uterine fibroids.
Methods: From October 2020 to December 2023, a total of 30 patients with symptomatic uterine fibroids (≥ 7 cm) who underwent US-PMWA with the assistance of a 3D visualization operative planning system were included in this retrospective study. A control group of 60 patients who underwent US-PMWA using conventional 2D image operative planning methods was also studied.
Comput Methods Programs Biomed
December 2024
Introduction: This study aimed to investigate the efficacy of a small-gauge microwave ablation antenna (MWA) with an enhanced cooling system (ECS) for generating more spherical ablation zones.
Methods: A comparison was made between two types of microwave ablation antennas, one with ECS and the other with a conventional cooling system (CCS). The finite element method was used to simulate in vivo ablation.
Objective: We aimed to assess the efficacy and safety of the three-dimensional visualization ablation planning system (3DVAPS) in ultrasound-guided percutaneous microwave ablation (US-PMWA) for malignant adrenal tumors (MATs).
Methods: A retrospective analysis was conducted on a cohort of 62 unilateral MAT cases from March 2011 to November 2022. There were a total of 62 lesions, with a mean maximum diameter of 5.
. This study aims to develop and assess a tumor contraction model, enhancing the precision of ablative margin (AM) evaluation after microwave ablation (MWA) treatment for hepatocellular carcinomas (HCCs)..
View Article and Find Full Text PDFTechnol Cancer Res Treat
November 2023
Background: Previous studies have failed to investigate the specific effects of advanced age on survival outcomes by considering the Charlson Comorbidity Index (CCI) and age permutation in patients with T1a renal cell carcinoma (T1a RCC) treated by microwave ablation (MWA). Notably, RCC guidelines recommended radiofrequency ablation (RFA) and active surveillance (AS) are both treatment options for elderly T1a RCC, but whether MWA is superior to AS in light of higher heating efficiency and larger ablation zone compared with RFA is not clear. This study aimed to investigate the specific effects of advanced age on survival outcomes of T1a RCC patients stratified by CCI score and indicate better intervention for elderly T1a RCC between MWA and AS.
View Article and Find Full Text PDFUltrasound Med Biol
October 2023
Objective: N-wire phantom-based ultrasound probe calibration has been used widely in many freehand tracked ultrasound imaging systems. The calibration matrix is obtained by registering the coplanar point cloud in ultrasound space and non-coplanar point cloud in tracking sensor space based on the least squares method. This method is sensitive to outliers and loses the coplanar information of the fiducial points.
View Article and Find Full Text PDFDespite being a common therapy for hepatocellular carcinoma (HCC), insufficient thermal ablation can leave behind tumor residues that can cause recurrence. This is believed to augment M2 inflammatory macrophages that usually play a pro-tumorigenic role. To address this problem, we designed d-mannose-chelated iron oxide nanoparticles (man-IONPs) to polarize M2-like macrophages into the antitumor M1 phenotype.
View Article and Find Full Text PDFBackground: High early recurrence (ER) of hepatocellular carcinoma (HCC) after microwave ablation (MWA) represents a sign of aggressive behavior and severely worsens prognosis. The aim of this study was to estimate the outcome of HCC following MWA and develop a response algorithmic strategy based on multiparametric MRI and clinical variables.
Methods: In this retrospective study, we reviewed the records of 339 patients (mean age, 62 ± 12 years; 106 men) treated with percutaneous MWA for HCC between January 2014 and December 2017 that were evaluated by multiparametric MRI.
Objectives: To investigate the changes in liver volume and function after microwave ablation (MWA) of hepatocellular carcinomas (HCCs).
Materials And Methods: We retrospectively analysed 76 patients with 106 nodules who underwent MWA for HCCs ≤5 cm between January 2015 and September 2017. Liver and ablation volumes were calculated using a three-dimensional visualisation system on MRI.
A novel intumescent flame retardant (IFR) agent designated as Dohor-6000A has been used to prepare halogen-free flame retardant polypropylene (PP) fibers via melting spinning. Before being blended with PP resin, a surface modification of Dohor-6000A was carried out to improve its compatibility with the PP matrix. The rheological behavior of flame retardant Dohor-6000A/PP resin, the structure, morphology, mechanical properties, flammability of the Dohor-6000A/PP fibers were studied in detail, as well as the action mode of flame retardant.
View Article and Find Full Text PDFBackground: The aim of this retrospective study was to compare the feasibility and efficiency of ultrasound-guided percutaneous microwave ablation (US-PMWA) assisted by three-dimensional visualization ablation planning system (3DVAPS) and conventional 2D planning for hepatocellular carcinoma (HCC) (diameter > 3 cm).
Methods: One hundred thirty patients with 223 HCC nodules (5.0 ± 1.
Background: To evaluate the value of a three dimension (3D)visualization operative planning system in ultrasound-guided percutaneous microwave ablation (US-PMWA) for large hepatic hemangiomas (LHHs).
Methods: Fifty-eight patients with LHHs were divided into 3D and 2D groups. The therapeutic efficacy was assessed by contrast-enhanced imaging during follow-up.
Purpose: We aimed to explore the feasibility of microwave ablation (MWA) assisted by three-dimensional visualization system for relapsed HB in children.
Methods: From August 2014 to February 2017, five patients with relapsed HB were enrolled. A total of 12 liver tumors were treated with MWA assisted by a three-dimensional visualization system.
Purpose: To evaluate the effects of ablation strategies on local tumor progression (LTP) after microwave ablation (MWA) of hepatocellular carcinomas (HCCs) measuring 3-5 cm.
Materials And Methods: Between December 2011 and May 2017, 71 HCC patients with 71 nodules treated by ultrasound(US)-guided percutaneous MWA were divided into parallel (group A) and crossed (group B) antenna placement groups. All patients underwent MWA using two antennas with four insertions.
Purpose: This study aimed to investigate the clinical value of a tumor map for assessing the ablative effect after ultrasound-guided percutaneous microwave ablation (US-PMWA) for hepatocellular carcinoma (HCC).
Methods: The medical records of 68 patients (49 male and 19 female, 59.9±12.
In order to improve the flame retardance of aromatic polyoxadiazole (-POD) fiber, a series of phosphorus-containing PODs (pho-POD) were synthesized by introducing triaryl phosphine oxide (TPO) units into the main chains of -POD using hydrazine sulfate, terephthalic acid and bis(-carboxy)phenyl phosphine oxide (BCPPO) as monomers, and then halogen-free flame resistant pho-POD fibers were obtained from wet spinning. The structure and properties of the pho-POD fibers were characterized and measured in detail using the methods of wide-angle X-ray diffraction (WAXD), scanning electron microscopy (SEM), thermogravimetric analysis (TGA), the limiting oxygen index (LOI), oxygen bomb calorimeter, Pyrolysis-Gas Chromatography/Mass Spectrometry (Py-GC/MS) The results show that the introduction of TPO units resulted in the weakening of the crystallization ability, the formation of the poriferous and lax interior structure, the slight decrease in the thermal stability and mechanical properties of the POD fibers. However, the value of LOI obviously increased from 28% to 35%, and the gross heat of combustion (GHC) decreased from 19.
View Article and Find Full Text PDFTo assess the clinical efficiency and feasibility of ultrasound-guided percutaneous microwave ablation (US-PMWA) assisted by a three-dimensional (3D) visualization platform for treating a single large hepatocellular carcinoma (HCC) (diameter ≥5 cm). We included 40 patients with a single large HCC from May 2015 to August 2017. Nineteen patients who underwent US-PMWA assisted by a 3D visualization platform formed the 3D group; 21 patients without 3D visualization assistance formed the control group.
View Article and Find Full Text PDFMurine models for rheumatoid arthritis (RA) research can provide important insights for understanding RA pathogenesis and evaluating the efficacy of novel treatments. However, simultaneously imaging both murine articular cartilage and subchondral bone using conventional techniques is challenging because of low spatial resolution and poor soft tissue contrast. X-ray phase-contrast imaging (XPCI) is a new technique that offers high spatial resolution for the visualisation of cartilage and skeletal tissues.
View Article and Find Full Text PDFBiomed Eng Online
July 2014
Background: Mechanical system with imperfect or misalignment of X-ray phase contrast imaging (XPCI) components causes projection data misplaced, and thus result in the reconstructed slice images of computed tomography (CT) blurred or with edge artifacts. So the features of biological microstructures to be investigated are destroyed unexpectedly, and the spatial resolution of XPCI image is decreased. It makes data correction an essential pre-processing step for CT reconstruction of XPCI.
View Article and Find Full Text PDFBiomed Eng Online
June 2014
Background: Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality worldwide, and emphysema is a common component of COPD. Currently, it is very difficult to detect early stage emphysema using conventional radiographic imaging without contrast agents, because the change in X-ray attenuation is not detectable with absorption-based radiography. Compared with the absorption-based CT, phase contrast imaging has more advantages in soft tissue imaging, because of its high spatial resolution and contrast.
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