Deep learning-based time series prediction in multispectral and hyperspectral imaging for cancer detection.

Introduction: Multispectral and hyperspectral imaging have emerged as powerful tools in medical diagnostics, particularly in cancer detection, due to their ability to capture rich spectral information beyond human vision. Traditional approaches for cancer detection rely on handcrafted features and conventional machine learning algorithms, which struggle with high-dimensional spectral data, noise interference, and domain adaptation challenges. Deep learning has recently been introduced to address these limitations, yet existing models often lack robust feature extraction, generalization capability, and effective domain adaptation strategies.

Transcription Factor LjWRKY50 Affects Jasmonate-Regulated Floral Bud Duration in .

Thunb. is a traditional Chinese medicinal herb whose floral buds are the primary source of pharmacological compounds that require manual harvesting. As a result, its floral bud duration, determined by the opening time, is a key determinant of both quality and economic value.

Elevated serum METRNL levels in children with obesity and its association with insulin resistance.

Unlabelled: Meteorin-like protein (METRNL) has emerged as a novel adipokine involved in metabolic regulation. However, its role in pediatric obesity and its relationship with insulin resistance remain largely unexplored. In this cross-sectional study, we enrolled 55 children with obesity (34 boys, 21 girls) and 49 normal-weight controls (31 boys, 18 girls).

On-road GHG emissions characteristics and durability of typical China-VI HDDVs in intercity transportation.

China confronts rising greenhouse gas (GHG) emissions from transportation sector, particularly under-addressed emissions from heavy-duty diesel vehicles (HDDVs), challenging its carbon neutrality goal by 2060. Using a portable emission measurement system (PEMS), the on-road CO, CH, and NO emissions characteristics and durability of seven typical China-VI HDDVs applied for intercity transportation were evaluated. A direct correlation was observed between increased instantaneous CO emissions and vehicle specific power (VSP), affirming the positive dependency of CO emissions on engine power.

Analysis of the impact of dexmedetomidine on the vital signs of patients with anxiety at various time intervals upon entering the operating room.

Objective: Investigating preoperative anxiety and its determinants among patients with gastrointestinal tumors, and assessing the efficacy of dexmedetomidine in improving vital signs among patients with moderate to severe anxiety.

Methods: A total of 100 patients scheduled for elective laparoscopic gastrointestinal tumor resection were included in the study. Preoperative data were collected, and anxiety levels were assessed.

Exosomes derived from adipose-derived stem cells alleviate acute radiation-induced dermatitis through up-regulating hyaluronic acid synthase 1 expression.

Background: Acute radiation-induced dermatitis refers to skin lesions that usually appear within 90 days of the start of radiotherapy. Although various treatments are available, none have proven fully effective. Exosomes produced by adipose-derived stem cells play crucial roles in enhancing cell regeneration, promoting angiogenesis, regulating inflammation and remodeling the extracellular matrix.

Botulinum Toxin Type A for Nostril Overexposure: A Prospective Clinical Study Using 3D Scanning.

Background: Nostril overexposure is a common aesthetic concern among Asian populations, which significantly affects facial harmony. Traditional surgical interventions carry risks such as substantial trauma and visible scarring. This study aims to evaluate the clinical efficacy of Botulinum Toxin Type A (BoNT-A) injections in treating nostril overexposure using three-dimensional (3D) scanning technology.

Application of collagen in bone regeneration.

At present, there is a significant population of individuals experiencing bone deficiencies caused by injuries, ailments affecting the bones, congenital abnormalities, and cancer. The management of substantial bone defects a significant global orthopedic challenge due to the intricacies involved in promoting and restoring the growth of fresh osseous tissue. Autografts are widely regarded as the "gold standard" for repairing bone defects because of their superior tissue acceptance and ability to control osteogenesis.

Fano and Electromagnetically Induced Transparency Resonances in Dual Side-Coupled Photonic Crystal Nanobeam Cavities.

We propose two types of structures to achieve the control of Fano and electromagnetically induced transparency (EIT) line shapes, in which dual one-dimensional (1D) photonic crystal nanobeam cavities (PCNCs) are side-coupled to a bus waveguide with different gaps. For the proposed type Ⅰ and type Ⅱ systems, the phase differences between the nanobeam periodic structures of the two cavities are and 0, respectively. The whole structures are theoretically analyzed via the coupled mode theory and numerically demonstrated using the three-dimensional finite-difference time-domain (3D FDTD) method.

Study on serum TL1A levels and their correlation with Th17 cells, IL-17 and IL-21 in children with Graves' disease.

Objective: To investigate serum TL1A levels and their correlation with Th17 cells, IL-17, and IL-21 in children with Graves' disease (GD).

Methods: Thirty-seven children (12 males and 25 females) aged 9-14 years with newly diagnosed and untreated GD were enrolled in this study. Serum TL1A, IL-17, and IL-21 levels were measured using enzyme-linked immunosorbent assay (ELISA).

Genome Sequencing and Comparative Genomic Analysis of Attenuated Strain GnVn.1 Causing Mild Wilt in Sunflower.

, previously classified in the genus until 2007, is an attenuated pathogen known to provide cross-protection against wilt in various crops. To investigate the potential mechanisms underlying its reduced virulence, we conducted genome sequencing, annotation, and a comparative genome analysis of GnVn.1 (GnVn.

3D Assessment of Mandibular Margin Morphological Change after BTX-A Injection for Masseter Hypertrophy: A Retrospective Study.

Background: Some facial morphological changes may occur in some patients after botulinum toxin A (BTX-A) injection for the treatment of masseteric hypertrophy. The aim of this study was to investigate the morphological changes that occurred on mandibular margin.

Methods: This retrospective analysis included 43 patients (86 lateral cases) who received BTX-A injections for masseter hypertrophy.

On-road measurement of post-catalyst ammonia emissions from gasoline and hybrid vehicles using quantum cascade laser detector.

Ammonia emissions from gasoline vehicles have been confirmed an essential precursor of urban secondary aerosols. To more comprehensively understand the formation mechanisms and better control vehicle-related ammonia, this paper measured the on-road ammonia emissions from six conventional and four hybrid vehicles using a state-of-the-art Quantum Cascade Laser analyzer on urban, rural, and highway routes. The test vehicles emitted 0.

Exosomal miR‑194 from adipose‑derived stem cells impedes hypertrophic scar formation through targeting TGF‑β1.

Hypertrophic scars, which result from aberrant fibrosis and disorganized collagen synthesis by skin fibroblasts, emerge due to disrupted wound healing processes. These scars present significant psychosocial and functional challenges to affected individuals. The current treatment limitations largely arise from an incomplete understanding of the underlying mechanisms of hypertrophic scar development.

Human adipose mesenchymal stem cell-derived exosomes alleviate fibrosis by restraining ferroptosis in keloids.

Background: Keloid is a fibroproliferative disease with unsatisfactory therapeutic effects and a high recurrence rate. exosomes produced by adipose-derived mesenchymal stem cells (ADSC-Exos) have attracted significant interest due to their ability to treat fibrosis. However, the molecular mechanisms of ADSC-Exos in keloids remain inconclusive.

Analysis of Whole-Genome for Identification of Seven Species with Significant Economic Value.

The genus exhibits a broad global distribution and holds substantial economic value in sectors including agriculture, industry, and medicine. Particularly in agriculture, species significantly impact plants, causing diseases and contamination that adversely affect crop yields and quality. Timely detection of species is crucial for controlling disease and preventing mycotoxins from entering the food chain.

Decelerating catalyst aging of natural gas engines using organic Rankine cycle under road conditions.

High exhaust temperature is an intrinsic nature of natural gas engines which underlies power de-rating and thermal aging of after-treatment system; therefore, this study integrates an organic Rankine cycle (ORC) system between engine and it's three-way catalyst (TWC) to address these challenges. ORC facilitates power output enhancement through exhaust energy recovery and alleviates thermal aging by reducing exhaust temperature. To estimate the effectiveness of this hypothesized system, a simulation-based investigation is performed.

Serum stromal cell-derived factor-1 concentrations are increased and associated with nonalcoholic fatty liver disease in children with obesity.

Introduction: Stromal cell-derived factor-1 (SDF-1) is a newly discovered small molecule adipocytokine, and research has shown that it is closely related to the occurrence and development of obesity. However, there are currently few research reports on SDF-1 in childhood obesity and nonalcoholic fatty liver disease (NAFLD), and this study aims to explore the relationship between SDF-1 and obesity related indicators in obese children.

Methods: Serum SDF-1 concentrations were measured using enzyme-linked immunosorbent assay (ELISA).

Disulfiram Improves Fat Graft Retention by Modulating Macrophage Polarization With Inhibition of NLRP3 Inflammasome-Mediated Pyroptosis.

Background: Macrophage-mediated inflammatory response in the early post-grafting period restricts fat graft retention. Pyroptosis is a novel type of programmed cell death that extensively participates in inflammatory pathologies.

Objectives: This study sought to determine whether macrophage pyroptosis was activated during the inflammatory phase after fat grafting and to investigate the efficacy of a pyroptosis inhibitor, disulfiram (DSF), in fat graft retention.

Analysis of Whole-Genome facilitates rapid and precise identification of fungal species.

Fungal identification is a cornerstone of fungal research, yet traditional molecular methods struggle with rapid and accurate identification, especially for closely related species. To tackle this challenge, we introduce a universal identification method called Analysis of whole GEnome (AGE). AGE includes two key steps: bioinformatics analysis and experimental practice.

Lineage-Specific CYP80 Expansion and Benzylisoquinoline Alkaloid Diversity in Early-Diverging Eudicots.

Menispermaceae species, as early-diverging eudicots, can synthesize valuable benzylisoquinoline alkaloids (BIAs) like bisbenzylisoquinoline alkaloids (bisBIAs) and sinomenines with a wide range of structural diversity. However, the evolutionary mechanisms responsible for their chemo-diversity are not well understood. Here, a chromosome-level genome assembly of Menispermum dauricum is presented and demonstrated the occurrence of two whole genome duplication (WGD) events that are shared by Ranunculales and specific to Menispermum, providing a model for understanding chromosomal evolution in early-diverging eudicots.

Analysis of Whole-Genome as a Novel Strategy for Animal Species Identification.

Survival crises stalk many animals, especially endangered and rare animals. Accurate species identification plays a pivotal role in animal resource conservation. In this study, we developed an animal species identification method called Analysis of whole-GEnome (AGE), which identifies species by finding species-specific sequences through bioinformatics analysis of the whole genome and subsequently recognizing these sequences using experimental technologies.

Identification of closely related species in through Analysis of Whole-Genome.

The challenge of discriminating closely related species persists, notably within clinical diagnostic laboratories for invasive aspergillosis (IA)-related species and food contamination microorganisms with toxin-producing potential. We employed Analysis of the whole-GEnome (AGE) to address the challenges of closely related species within the genus and developed a rapid detection method. First, reliable whole genome data for 77 species were downloaded from the database, and through bioinformatic analysis, specific targets for each species were identified.

Compact mode converter on SOI based on a polygonal subwavelength grating structure.

In this Letter, we design and experimentally demonstrate compact mode converters with a lightning-like and arrow-like polygonal subwavelength grating (SWG) structure on a silicon-on-insulator (SOI) platform, which can convert the TE mode to the TE and TE modes, respectively. The footprints of the proposed TE and TE mode converters are only 4.44 × 1.