Topological edge states of plasmonic dark mode in one-dimensional split-ring nanochains.

Topological plasmonics play a crucial role in advancing both fundamental physics and photonics applications. While research has primarily concentrated on topological edge states (TESs) associated with plasmon bright mode, the significant emission dissipation linked to these states limits enhancements in near-field performance. Conversely, TESs based on dark mode offer the promise of increased local field enhancement and reduced emission loss, potentially improving near-field characteristics.

Wide-range control of surface plasmon dephasing time by the strong coupling between surface lattice and gap modes.

In applications such as plasmonic sensors and plasmonic nanolasers, constructing metal nanostructures with a wide range of tunability of plasmonic dephasing times is becoming increasingly important. However, the manipulation range of the dephasing time is still limited from only a few femtoseconds to tens of femtoseconds. Here, we propose what we believe to be a novel method to greatly extend the tunable range of plasmonic dephasing time by leveraging the strong coupling between the plasmonic gap mode and the surface lattice resonance mode.

Reverse Effects of Nicotinamide Mononucleotide Supplementation on Declining Quality of Oocytes With Polycystic Ovary Syndrome.

Polycystic ovary syndrome (PCOS) adversely impacts oocyte quality, underscoring effective interventions as a central focus of research. Our study demonstrates that nicotinamide mononucleotide (NMN) not only restores NAD homeostasis in oocytes from PCOS mice but also enhances the developmental rate of PCOS oocytes during in vitro maturation (IVM). Transcriptomic analysis and experimental validation suggest that NMN helps reverse the decline in PCOS oocyte quality by mitigating oxidative stress, improving mitochondrial function, and preserving spindle morphology.

Advances in immunotherapy and targeted therapy for advanced clear-cell renal cell carcinoma: current strategies and future directions.

Renal cell carcinoma (RCC), particularly the clear-cell subtype (ccRCC), accounts for 75-85% of kidney cancers and exhibits distinct genetic and biological heterogeneity. While surgical resection remains the mainstay of treatment for localized ccRCC, the persistence of recurrence rates underscores the significant unmet need for effective adjuvant therapies. Recent advancements in immunotherapy and targeted therapies have revolutionized the management of RCC.

Association between sarcopenic obesity and dementia in the Chinese elderly using different definitions of obesity: evidence from the CHARLS.

Objectives: The prevalence of sarcopenic obesity, characterized by the coexistence of reduced muscle mass and function alongside increased adipose tissue, is increasing in the aging population. This study aims to investigate the association between sarcopenic obesity and dementia risk in community-dwelling older adults in China, utilizing a nationally representative dataset. Furthermore, we aim to assess the comparative effectiveness of waist circumference versus body mass index as indicators for assessing this risk association.

Characteristics of photoemission from radiative and sub-radiative localized surface plasmons in metal nanostructures.

Revealing the mechanism of photoemission from plasmonic nanostructures that supports different localized surface plasmon modes is crucial for designing new ultrafast photoelectric cathodes, as well as for enhancing localized surface plasmon (LSP)-based photocatalysis, energy harvest, and photoluminescence, but the investigation on this topic is still lacking. In this paper, we directly investigated the photoemission yield and photoemission mechanism from a sub-radiative Fano mode in an asymmetric nanorod dimer, a radiative dipole mode in an isolated nanorod, and a radiative coupled dipole mode in a symmetric nanorod dimer, respectively, using time-of-flight photoemission electron microscopy. We found that the photoemission yield from the sub-radiative Fano mode is almost equal to that of the radiative dipole mode but more than four times higher than that of the radiative coupled dipole mode case.

DNA Sensors for the Detection of Mercury Ions.

Ecosystem pollution by mercury ions (Hg) is a major health concern, yet classical analytical methods for mercury analysis are limited. This paper reviews the advances in Hg detection using DNA as recognition elements in the sensors. DNA as a recognition molecule is inexpensive, simple, and appropriate for real-time detection of Hg.

Perioperative care and recovery outcome of deep jugular venous lymphatic anastomosis in Alzheimer's disease: A case report.

This case reports a 74-year-old female from eastern China presented with memory loss, dyscalculia, language disorders, diagnosed with Alzheimer's disease and underwent deep cervical venous lymphatic anastomosis. After rigorous preoperative evaluation, surgical treatment, and postoperative care, the patient had no postoperative care-related complications and showed obvious improvement in her language and self-care skills. The patient's Mini-Mental State Examination score improved three months after surgery compared to the preoperative period (5 versus 0).

Role of ZBED3 in PALD1/PIP2- dependent calcium homeostasis during oocyte maturation.

Zinc Finger BED-Type Containing 3 (ZBED3) had been shown to be a novel component of the subcortical maternal complex (SCMC). In previous reports, ZBED3 depletion leads to asymmetric zygotic division and aberrant distribution of organelles in both oocytes and zygotes. However, the precise mechanism through which ZBED3 exerts its effects remains to be elucidated.

Making Diet Management Easier: The Effects of Nudge-Based Dietary Education and Tableware in Individuals with Both T2DM and Overweight/Obesity: A 2 × 2 Cluster Randomized Controlled Trial.

Background/objectives: Traditional diet management for type 2 diabetes (T2DM) is often complex and effortful to sustain. Nudging offers low-effort and automatic approaches to dietary behaviour change yet remains underexplored in T2DM. This study evaluated the independent and combined 6-month effects of nudging education (NE) and nudging tableware (NT) on HbA1c, along with other secondary health outcomes, among adults with T2DM and overweight/obesity, compared to their non-nudge counterparts (control education, CE; control tableware, CT).

Group-Based Trajectory Modeling of Platelet in Patients with Aplastic Anemia: A Study Based on the MIMIC Database.

Background: Platelets are the main components supporting coagulation and hemostasis. Nevertheless, no sufficient research has been done on how variations in platelet counts during hospital stays affect aplastic anemia (AA) patients' prognoses.

Objective: This study proposes to evaluate the association between alterations in platelet levels and illness risk in patients with AA using group-based trajectory modeling (GBTM).

Polaron formation by electron polarization in two-dimensional transition metal halides.

An electron in solid can be dressed by the lattice distortions of surroundings, forming a localized composite quasiparticle called small polaron, whose formation has been customarily attributed to the electron-phonon couplings that the ion polarization traps the excess electron. Here we present a theory of electron-polarization induced small polaron, in which the carrier localization happens spontaneously and drives subsequent ion relaxation. This mechanism of polaron formation is qualitatively different than the Mott-Stoneham picture in that there is no need to overcome a kinetic barrier for the carrier to self-trap to form a polaron.

Multi-target regulatory effects of rhaponticin in a rat model of hepatic fibrosis revealed by non-targeted metabolomics.

Introduction: Hepatic fibrosis (HF), a progressive chronic liver disease, is a serious threat to global public health. The lack of preventive and therapeutic strategies has created an urgent need for effective anti-fibrosis agents. There is growing evidence that natural products might provide safe and effective interventions for HF.

Flowering in the Northern Hemisphere is delayed by frost after leaf-out.

Late spring frosts, occurring after spring phenological events, pose a dire threat to tree growth and forest productivity. With climate warming, earlier spring phenological events have become increasingly common and led to plants experiencing more frequent and severe frost damage. However, the effect of late spring frosts after leaf-out on subsequent flowering phenology in woody species remains unknown.

Revealing the Interlayer Interaction Forces in 2D Graphene Materials by Graphene-Wrapped Nanoprobe.

Understanding the interlayer interaction between 2D layered structures is critical for the construction of various micro- and nanoscale functional devices. However, both the normal and the tangential interlayer interactions between 2D layered materials have rarely been studied simultaneously. In this work, an immersion and lift-up method is proposed to wrap a layer of graphene flakes onto a plasma-pretreated atomic force microscopy (AFM) nanoprobe for the measurements of interaction forces by AFM.

Phylogenomics resolves a 100-year-old debate regarding the evolutionary history of caddisflies (Insecta: Trichoptera).

Trichoptera (caddisfly) phylogeny provides an interesting example of aquatic insect evolution, with rich ecological diversification, especially for underwater architecture. Trichoptera provide numerous critical ecosystem services and are also one of the most important groups of aquatic insects for assessing water quality. The phylogenetic relationships of Trichoptera have been debated for nearly a century.

All-Optical Control of Ultrafast Switching between the Hybridized Plasmonic Fields of Au Nanorod Dimer in fs-nm Scale with Dispersed Femtosecond Laser.

With the increasing demand for ultrafast communication and information processing in future optical chips, arbitrary manipulation of electromagnetic fields in the femtosecond-nanometer spatiotemporal scale has attracted great attention in integrated optics. Manipulation of the nanoscale light field in the real femtosecond temporal domain is challenging work. Here, we have demonstrated all-optical control of ultrafast switching between the hybridized plasmonic fields of a Au nanorod dimer in the fs-nm scale using a dispersed femtosecond laser and revealed the transformation process with ultrahigh spatiotemporal resolved technology via the combination of a pump-probe technique and photoemission electron microscopy (PEEM).

Associations of Handgrip Strength Weakness and Asymmetry with Lower Cognitive Function: Results from the National Health and Nutrition Examination Survey (2011-2014).

Background: The joint associations of handgrip strength (HGS) weakness and asymmetry with cognitive decline remain understudied in older adults.

Objective: To investigate the associations between HGS weakness, asymmetry, and lower cognitive function in a nationally representative sample of older Americans.

Methods: This cross-sectional study utilized data from the National Health and Nutrition Examination Survey 2011-2014.

Increased Angio-Derived Index of Microcirculatory Resistance Within a Timeframe of 30-60 days After COVID-19 Infection.

Background And Objectives: Chest pain is a relatively long-term symptom that commonly occurs in patients who have contracted COVID-19. The reasons for these symptoms remain unclear, with coronary microvascular dysfunction (CMD) emerging as a potential factor. This study aimed to assess the presence of CMD in these patients by measuring the angio-derived index of microcirculatory resistance (AMR).

Construction of a nursing assessment framework for patients in anaesthesia recovery period: A modified Delphi study.

Aim: To construct a nursing assessment framework for patients in anaesthesia recovery period.

Design: A three-round modified Delphi method was employed to capture the consensus of 22 panellists.

Methods: The initial items in the nursing assessment framework for patients in anaesthesia recovery period were developed based on the mini-clinical evaluation exercise (mini-CEX).

Chromosome-scale genome assemblies of Himalopsyche anomala and Eubasilissa splendida (Insecta: Trichoptera).

Trichoptera is one of the most evolutionarily successful aquatic insect lineages and is highly valued value in adaptive evolution research. This study presents the chromosome-level genome assemblies of Himalopsyche anomala and Eubasilissa splendida achieved using PacBio, Illumina, and Hi-C sequencing. For H.

Seven new species and four new records of Psychomyiidae (Insecta, Trichoptera) from China.

Seven new species of the family Psychomyiidae Walker, 1852 are described and illustrated from China; they are , , , , , , and The genus is reported for the first time from mainland China. In addition, four psychomyiids are found to be new to the Chinese caddis fauna: Malicky & Chantaramongkol, 1993; Malicky, 1979; Malicky & Chantaramongkol, 1993; and Johanson & Oláh, 2008. Moreover, Li, Qiu & Morse, 2021 is reviewed and synonymized with Malicky, 2020.

Deciphering driver regulators of cell fate decisions from single-cell transcriptomics data with CEFCON.

Single-cell technologies enable the dynamic analyses of cell fate mapping. However, capturing the gene regulatory relationships and identifying the driver factors that control cell fate decisions are still challenging. We present CEFCON, a network-based framework that first uses a graph neural network with attention mechanism to infer a cell-lineage-specific gene regulatory network (GRN) from single-cell RNA-sequencing data, and then models cell fate dynamics through network control theory to identify driver regulators and the associated gene modules, revealing their critical biological processes related to cell states.

[Levels and Clinical Significances of sPD-1 and sPD-L1 in Peripheral Blood of Lymphoma Patients].

Objective: To observe the levels of soluble programmed cell death protein 1 (sPD-1) and soluble programmed cell death ligand 1 (sPD-L1) in peripheral blood of lymphoma patients, and reveal their clinical significances.

Methods: The peripheral blood specimens and clinical data of 64 newly diagnosed lymphoma patients and 30 healthy volunteers were collected. The levels of sPD-1 and sPD-L1 were detected by enzyme-linked immunosorbent assay (ELISA), and their correlations with clinical characteristics of the patients including pathological type, stage, lactate dehydrogenase (LDH) level, T cell subsets were analyzed.