Putative SET domain-containing proteins play significant roles in regulating sporulation and pathogenicity in Phytophthora capsici.

Phytophthora capsici is a filamentous oomycete responsible for root rot, fruit rot, leaf blight, and other economically destructive diseases in multiple plant species, including pepper (Capsicum annuum), tomato (Solanum lycopersicum), squash (Cucurbita pepo), eggplant (Solanum melongena), faba bean (Vicia faba), and lima bean (Phaseolus lunatus), among others. The pathogen causes significant yield losses in fruit and vegetable crops globally. Multiple molecular parameters, including effector proteins and epigenetic modulators, play vital roles in modulating the physio pathological development of P.

Solar-Driven Atmospheric Water Production Through Hierarchically Ordered Porous Carbon for Self-Sustaining Green Hydrogen Production.

Green hydrogen production by proton exchange membrane water electrolysis (PEMWE) powered by clean energy is a promising and environmentally friendly technology. However, it relies on a high-purity water source, which is limited in regions facing water scarcity. Here, a coupled self-sustaining solar-enabled system is reported that couples atmospheric water harvesting with PEM water electrolysis (AWH-PEMWE), offering a novel pathway for clean water generation and green hydrogen production.

Ultrasound-Assisted Dispersive Solid-Phase Filter Extraction Coupled with Green Supercritical Fluid Chromatography Methodology for Simultaneous Determination of Hindered Phenolic Antioxidant Migration from Food Contact Materials.

The migration of hindered phenolic antioxidants from food contact materials (FCMs) into foodstuffs poses health risks due to endocrine disruption and organ toxicity. Hence, the development of a high-efficiency analytical method for hindered phenolic antioxidants is of great importance for food safety. This study developed a novel ultrasound-assisted dispersive solid-phase filter extraction (d-SPFE) coupled with green supercritical fluid chromatography (SFC) method for the simultaneous determination of six representative hindered phenolic antioxidants.

Identifying Key Predictors of Smoking Cessation Success: Text-Based Feature Selection Using a Large Language Model.

Background: The most effective way to reduce mortality and morbidity among current smokers is to quit smoking. Although about half of smokers attempted to quit, only one-tenth succeeded in 2022.

Objective: To identify key predictors of smoking cessation success to inform cessation interventions and increase quitting rates.

An Automated and Precise Approach for the Determination of Azide Residue in Angiotensin II Receptor Blockers Using In Situ Matrix Elimination Ion Chromatography with Switching Strategy.

Angiotensin II receptor blockers (ARBs), a critical class of second-generation antihypertensive drugs, require azide intermediates for constructing their biphenyl tetrazole pharmacophore. This synthetic reaction introduces hypertoxicity risks, as residual azides can induce fatal damage even at trace concentrations. The pharmacopoeias of most countries have highlighted the urgency for improved detection paradigms of the control of azides in ARBs.

Circulating RIPK3 level predicts all-cause mortality in patients on maintenance hemodialysis: a 4-year prospective cohort study.

Background: Maintenance hemodialysis (MHD) is a well-established modality of renal replacement treatment for patients with end-stage renal disease. Currently, receptor-interacting protein kinase-3 (RIPK3) is considered as a key regulator of inflammation. But its association with mortality in MHD patients remains unclear.

Spectroscopic techniques combined with chemometrics for rapid detection of food adulteration: Applications, perspectives, and challenges.

Food adulteration is an important threat to food safety and can be difficult to detect. Some analytical methods are complex and difficult to meet the needs of large numbers of samples. In this study, we introduced the application of six spectroscopic techniques (NIR, FTIR, HSI, Raman, UV-Vis, and FS) and chemometric methods in common food adulteration (powdered food, meat, honey, drink, edible oil, and dairy product) over the last three years.

Herbivory-induced green leaf volatiles increase plant performance through jasmonate-dependent plant-soil feedbacks.

Plants influence each other chemically by releasing leaf volatiles and root exudates, but whether and how these two phenomena interact remains unknown. Here we demonstrate that volatiles that are released by herbivore-attacked leaves trigger plant-soil feedbacks, resulting in increased performance of different plant species. We show that this phenomenon is due to green leaf volatiles that induce jasmonate-dependent systemic defence signalling in receiver plants, which results in the accumulation of beneficial soil bacteria in the rhizosphere.

A Novel Column-Switching Method Coupled with Supercritical Fluid Chromatography for Online Analysis of Bisphenol A Diglycidyl Ether and Its Derivatives in Canned Beverages.

Bisphenol A diglycidyl ether (BADGE) and its related derivatives (BADGEs for short) are reactive epoxides condensed from bisphenol A (BPA) and epichlorohydrin. Nowadays, they are heavily used as additives in the production process of food and beverage contacting materials. However, BADGEs are considered as emerging organic pollutants due to their high toxicity including cytotoxicity, mutagenicity, and genotoxicity.

Recent progress in the application of chromatography-coupled mass-spectrometry in the analysis of contaminants in food products.

An increasing concern has marked the past few years for food quality and safety, not only by the research community but also among the general public. Due to the increasing prevalence of emerging contaminants/analogues in various food matrices, significant efforts have been focused on developing green extraction, matrix preparation, multi-targeted, and potentially multi-matrix techniques that minimize waste generation, cost, and the use of organic reagents to optimize recyclability throughout the analytical procedure. This, therefore, not only guarantees consumer protection through food safety but also contributes to progress in green analysis, ultimately preventing the one-step forward and two-steps back phenomenon of ensuring food safety while damaging the environment.

The role of SLC12A3 gene variant c.1964G > A in co-existing Gitelman syndrome and unilateral limb paralysis: a case report and literature review.

We report a Gitelman syndrome (GS) pedigree from a Chinese family. The proband, a middle-aged man, presented with hypokalemia, hypomagnesemia, and unilateral limb paralysis. After a comprehensive evaluation, peripheral neuropathy and the cranial or spinal cord disorders were ruled out.

MAIT Cells Promote Cholesterol Excretion Pathways Mitigating Atherosclerosis.

Background: Previous clinical studies have indicated reduced circulating mucosal-associated invariant T (MAIT) cells in individuals with coronary artery disease. However, the precise role and underlying mechanisms of MAIT cells in this context remain unclear. Immune homeostasis plays a pivotal role in the development of atherosclerosis.

Study on the regularity of blood pressure changes in pregnant women and its influencing factors.

Objective: To explore the patterns and influencing factors of blood pressure changes in pregnant women at different stages of pregnancy.

Method: A retrospective analysis of 445 pregnant women who underwent prenatal examination and delivered at the First Hospital of Hebei Medical University between December 2016 and November 2017. A questionnaire survey was conducted on pre-pregnancy information, and data was collected from pre-pregnancy blood routines, blood lipids, cortisol levels, and other biochemical indicators, as well as blood pressure measurements taken before pregnancy, in early pregnancy, mid-pregnancy, and late pregnancy.

Effects and functional mechanisms of digital fitness platforms on online fitness payment behavior under the perspective of "She-economy".

Women have become an important force for economic development. Online fitness payment behavior is an important part of women's pursuit of "beautiful skin and healthy body", and is also an important embodiment of the integration of the digital industry and the fitness industry. Based on Stimuli-Organism-Response and Technology Acceptance Model theories, this study systematically explored the relationship and mechanism of action between digital fitness platforms and online fitness payment behavior through a survey of 259 women using Structural Equation Modeling and Fuzzy Set Qualitative Comparative Analysis.

Construction of Multifunctional Composite Films with Biomimetic Bridging and Stress Dissipation Properties.

Strategies based on biodegradable polymers to replace traditional petroleum-based plastics have become research hotspots, while designing multifunctional composite films as packaging materials remains a challenging task. Herein, mussel-inspired hollow mesoporous polydopamine (HMPDA) is prepared and used as a secondary reaction platform to immobilize silver nanoparticles (HMPDA@Ag), which are then co-doped into a polyvinyl alcohol (PVA) matrix in combination with naturally derived 2D montmorillonite (MMT). Benefiting from the noncovalent interactions between the composite particles and MMT with the PVA matrix, as well as the synergistic effects between nanofillers, the fabricated films exhibit a great tensile strength of 424.

Nanoscale Structure and Interfacial Electrochemical Reactivity of Moiré-Engineered Atomic Layers.

ConspectusThe electronic properties of atomically thin van der Waals (vdW) materials can be precisely manipulated by vertically stacking them with a controlled offset (for example, a rotational offset─i.e., twist─between the layers, or a small difference in lattice constant) to generate moiré superlattices.

One-step construction of bioinspired multi-enzyme mimicking nanozyme as a universal platform for multi-mode sensing and catalytic degradation.

Nanozymes, a category of nanomaterials with exceptional enzyme-like activity, exhibit the significant promise to overcome the inherent limitations of natural enzymes. Inspired by the active site structure of natural laccase, a biomimetic MA-Cu nanozyme with three-dimensional network structure was constructed in water system through one-step complexation based on the specific coordination between nitrogen-rich triazine heterocyclic melamine and Cu, in a facile, green and economical manner. Compared to natural laccase, MA-Cu possesses superior multi-enzyme mimicking activity, stability and cost-effectiveness.

Three-birds-with-one-stone: An eco-friendly and renewable humic acid-derived material application strategy for macrolide antibiotic detection and multifunctional composite film preparation.

This research proposes a simple and novel strategy for the green detection of antibiotics along with the reduction of microplastic and humic acid (HA) hazards. The entire process is based on a single-step solvent-sieving method to separate HA into insoluble (IHA) and soluble (SHA) components, subsequently recombining and designing the application according to the original characteristics of selected fractions in accordance with the zero-waste principle. IHA was applied as a dispersive solid phase extraction (DSPE) sorbent without chemical modification for the enrichment of trace MACs in complex biological matrices.

Local atomic stacking and symmetry in twisted graphene trilayers.

Moiré superlattices formed by twisting trilayers of graphene are a useful model for studying correlated electron behaviour and offer several advantages over their formative bilayer analogues, including a more diverse collection of correlated phases and more robust superconductivity. Spontaneous structural relaxation alters the behaviour of moiré superlattices considerably and has been suggested to play an important role in the relative stability of superconductivity in trilayers. Here we use an interferometric four-dimensional scanning transmission electron microscopy approach to directly probe the local graphene layer alignment over a wide range of trilayer graphene structures.

Deep learning-based prediction of coronary artery calcium scoring in hemodialysis patients using radial artery calcification.

Objective: This study used random forest model to explore the feasibility of radial artery calcification in prediction of coronary artery calcification in hemodialysis patients.

Material And Methods: We enrolled hemodialysis patients and performed ultrasound examinations on their radial arteries to evaluate the calcification status using a calcification index. All involved patients received coronary artery computed tomography scans to generate coronary artery calcification scores (CACS).

Strain-modulated Ru-O Covalency in Ru-Sn Oxide Enabling Efficient and Stable Water Oxidation in Acidic Solution.

RuO is one of the benchmark electrocatalysts used as the anode material in proton exchange membrane water electrolyser. However, its long-term stability is compromised due to the participation of lattice oxygen and metal dissolution during oxygen evolution reaction (OER). In this work, weakened covalency of Ru-O bond was tailored by introducing tensile strain to RuO octahedrons in a binary Ru-Sn oxide matrix, prohibiting the participation of lattice oxygen and the dissolution of Ru, thereby significantly improving the long-term stability.

Dealuminated Beta zeolite reverses Ostwald ripening for durable copper nanoparticle catalysts.

Copper nanoparticle-based catalysts have been extensively applied in industry, but the nanoparticles tend to sinter into larger ones in the chemical atmospheres, which is detrimental to catalyst performance. In this work, we used dealuminated Beta zeolite to support copper nanoparticles (Cu/Beta-deAl) and showed that these particles become smaller in methanol vapor at 200°C, decreasing from ~5.6 to ~2.

Comparison of exenatide alone or combined with metformin versus metformin in the treatment of polycystic ovaries: a systematic review and meta-analysis.

Background: Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility in women of childbearing age. Randomized controlled trials (RCTs) have reported that exenatide and metformin are effective in the treatment of PCOS. In this meta-analysis, we aimed to compare the effectiveness and safety of exenatide alone or in combination with metformin versus metformin in patients suffering from PCOS.