A Novel Scheme for High-Accuracy Frequency Estimation in Non-Contact Heart Rate Detection Based on Multi-Dimensional Accumulation and FIIB.

This paper proposes a novel heart rate detection scheme to address key challenges in millimeter-wave radar-based vital sign monitoring, including weak signals, various types of interference, and the demand for high-precision and super-resolution frequency estimation under practical computational constraints. First, we propose a multi-dimensional coherent accumulation (MDCA) method to enhance the signal-to-noise ratio (SNR) by fully utilizing both spatial information from multiple receiving channels and temporal information from adjacent range bins. Additionally, we are the first to apply the fast iterative interpolated beamforming (FIIB) algorithm to radar-based heart rate detection, enabling super-resolution frequency estimation with low computational complexity.

Octenyl Succinic-Modified Starch Complexes with Dipalmitoyl Glycerol Isomers.

Starch-lipid complexes are generating great research interest due to their promising health benefits. However, there remains a big challenge for preparing typical V-type crystalline starch-diacylglycerol or triacylglycerol complexes. In this study, two diacylglycerol (DAG) isomers ((1,2 dipalmitoyl glycerol; 1,2 DPG) and (1,3 dipalmitoyl glycerol; 1,3 DPG)) were used to prepare the V-type crystalline starch-lipid complexes and to understand the role of molecular conformation in the formation of starch-DAG complexes using a modified previous protocol in which the complexing parameters were optimized.

Difference between cystatin C- and creatinine-based estimated glomerular filtration rate, diabetes status, and incident peripheral artery disease: A population-based cohort study.

Background And Aims: Difference between cystatin C and creatinine-based estimated glomerular filtration rate (eGFRdiff) has been suggested to reflect factors that are associated with vascular risk, independent of kidney function. We aimed to prospectively evaluate the association between eGFRdiff and peripheral artery disease (PAD), as well as the potential modifying role of diabetes.

Methods: This prospective cohort study included 466,245 participants with concurrent measured serum creatinine and cystatin C and free of PAD at baseline (2006-2010) from the UK Biobank.

Microdissection testicular sperm extraction-intracytoplasmic sperm injection strategy in patients with Klinefelter syndrome: synchronous or asynchronous?

Objective: The objective of this study was to compare the clinical outcomes of intracytoplasmic sperm injection (ICSI) with fresh versus cryopreserved sperm retrieved via microdissection testicular sperm extraction (mTESE) in patients with Klinefelter syndrome (KS).

Design: A retrospective cohort study was conducted.

Setting: This study was performed at the Reproductive Medicine Center of Henan Provincial People's Hospital.

The prognostic value of admission serum uric acid for acute kidney injury: a two-center retrospective analysis.

Background: Acute kidney injury (AKI) is a serious clinical syndrome, with elevated serum uric acid (SUA) recognized as a potential modifiable risk factor. Nonetheless, the association between reduced SUA and the risk of AKI, along with the modification by kidney function on this association, is not well understood.

Methods: All adult patients from Peking University First Hospital (PKUFH) were screened.

Machine learning unveils hypoxia-immune gene hub for clinical stratification of thyroid-associated ophthalmopathy.

Thyroid-associated ophthalmopathy (TAO) is an autoimmune disorder affecting the orbit, potentially resulting in blindness. This study focused on the role of hypoxia in its pathogenesis through integrative bioinformatics and experimental validation. Five differentially expressed genes associated with hypoxia (HRDEGs) were identified via Gene Expression Omnibus (GEO) database mining: AGO2, CP, DIO3, PSMD14, WTIP.

How aging impacts cortical dynamics and gait during dual-task turning revealed by fNIRS.

The aim of this study is to explore the differences in cortical activation and gait performance during turning walking under cognitive dual-task conditions between young and older adults during cognitive-turning dual task walking, as well as variations in brain functional connectivity in this context. Seventeen young adults and seventeen older adults were included in the study. All participants completed two tasks: a figure-eight turning walk (single-task, ST) and a figure-eight turning walking while performing a digital alert cognitive task (dual-task, DT).

Executive summary for the China Kidney Disease Network (CK-NET) 2017-2018 Annual Data Report.

Chronic kidney disease (CKD) has become a public health issue. Rapid urbanization in China has been intimately linked to shifts in the spectrum of CKD, particularly as regards CKD related to diabetes mellitus. By amalgamating diverse data streams and harnessing cutting-edge technologies, the China Kidney Disease Network aspires to evolve into a comprehensive surveillance framework for kidney diseases in China.

Zwitterion nanocomposite hydrogels with bioactivity and anti-adhesion properties for rapid prevention of postoperative and recurrent adhesion.

Postoperative adhesions (PAs) are a common complication after intraperitoneal surgery. Hydrogels are a physical barrier that prevents peritoneal adhesions, but their efficacy is still controversial. In this study, Laponites, a layered two-dimensional nanoscale, is incorporated into zwitterionic hydrogel (pSBLA) to enhanced biocompatibility and bioactivity to develop a nanocomposite for rapid prevention of postoperative and recurrent adhesion.

EML-SlowFast: A behavior recognition model for lion-head goose.

The behavior of lion-head goose has a significant impact on their health status, activity levels, and productivity. It is therefore important to monitor the behavior of lion-head geese to enhance their health status, reproductive performance, and overall productivity. However, there is currently no specific behavioral recognition method for lion-head goose, which presents a significant challenge in quickly and effectively identifying various behaviors.

Cost-effectiveness of population-based screening for chronic kidney disease among the general population and adults with diabetes in China: a modelling study.

Background: Despite the majority of patients with chronic kidney disease (CKD) live in low- and middle-income countries, most evidence on screening strategies is derived from high-income countries, where the contexts differ significantly. This study aims to assess the cost-effectiveness of population-based CKD screening strategies in both the general population and adults with diabetes in China.

Methods: A validated microsimulation model of CKD was developed to evaluate the costs and health consequences of population-based CKD screening strategies from a societal perspective.

External Validation of the Simple Postoperative Acute Kidney Injury Risk Index in Patients Admitted to the Intensive Care Unit After Noncardiac Surgery.

Background: The Simple Postoperative AKI Risk (SPARK) index is a novel model for predicting risk of postoperative acute kidney injury (PO-AKI) among patients after noncardiac surgery. However, the performance of the index has been inconsistent partly due to heterogeneity in case mix and effects of the involved clinical features. To clarify potential reasons for poor performance, we tested the SPARK index in a cohort of high-risk patients requiring intensive care unit (ICU) care after noncardiac surgery and examined whether model modification by refitting coefficients of clinical features could optimize model performance.

A dual-stream model based on PRNU and quaternion RGB for detecting fake faces.

The forensic examination of AIGC(Artificial Intelligence Generated Content) faces poses a contemporary challenge within the realm of color image forensics. A myriad of artificially generated faces by AIGC encompasses both global and local manipulations. While there has been noteworthy progress in the forensic scrutiny of fake faces, current research primarily focuses on the isolated detection of globally and locally manipulated fake faces, thus lacking a universally effective detection methodology.

Does Nonsteroidal Anti-inflammatory Drug Use Modify All-Cause and Cause-Specific Mortality Associated with PM and Its Components? A Nationally Representative Cohort Study (2007-2017).

Several studies reported that nonsteroidal anti-inflammatory drug (NSAID) use could alleviate subclinical effects of short-term exposure to fine particulate matter (PM). However, whether chronic NSAID use could mitigate the long-term effects of PM and its components on population mortality has been unknown. Based on a national representative survey of 47,086 adults (2007-2010) with follow-up information on the primary cause of death (until 2017), we investigated the long-term associations of PM and its major components, including black carbon (BC), ammonium (NH ), nitrate (NO ), organic matter (OM), and sulfate (SO ), with all-cause and cause-specific mortality using the Cox proportional hazards model.

Covalent inhibitors of the RAS binding domain of PI3Kα impair tumor growth driven by RAS and HER2.

Genetic disruption of the RAS binding domain (RBD) of PI 3-kinase (PI3K) prevents the growth of mutant RAS driven tumors in mice and does not impact PI3K's role in insulin mediated control of glucose homeostasis. Selectively blocking the RAS-PI3K interaction may represent an attractive strategy for treating RAS-dependent cancers as it would avoid the toxicity associated with inhibitors of PI3K lipid kinase activity such as alpelisib. Here we report compounds that bind covalently to cysteine 242 in the RBD of PI3K p110α and block the ability of RAS to activate PI3K activity.

Development and validation of a real-time prediction model for acute kidney injury in hospitalized patients.

Early prediction of acute kidney injury (AKI) may provide a crucial opportunity for AKI prevention. To date, no prediction model targeting AKI among general hospitalized patients in developing countries has been published. Here we show a simple, real-time, interpretable AKI prediction model for general hospitalized patients developed from a large tertiary hospital in China, which has been validated across five independent, geographically distinct, different tiered hospitals.

Recent Progress in Block Copolymer Self-Assembly for the Fabrication of Structural Color Pigments.

The self-assembly of block copolymers (BCPs) into photonic materials has garnered increasing interest due to the versatility and ease of fabrication offered by the synthesized building blocks. BCPs are highly tunable, with their self-assembled structures' size being adjustable by modifying the block lengths, molecular weight(M), and polymer composition. This review provides a concise summary of the use of BCPs as photonic pigments, which generate color through structural manipulation rather than relying on chemical pigmentation.

Research progress on the relationship between traumatic brain injury and brain-gut-microbial axis.

Traumatic brain injury (TBI) is a common disease with a high rate of death and disability, which poses a serious threat to human health; thus, the effective treatment of TBI has been a high priority. The brain-gut-microbial (BGM) axis, as a bidirectional communication network for information exchange between the brain and gut, plays a crucial role in neurological diseases. This article comprehensively explores the interrelationship between the BGM axis and TBI, including its physiological effects, basic pathophysiology, and potential therapeutic strategies.

Extreme temperature events, "Life's Essential 8", and prevalence of chronic kidney disease: A nationally representative surveillance in China.

The population disease burden caused by extreme temperature events has been increasing. However, research on the long-term effects of extreme temperature events on chronic kidney disease (CKD), as well as the combined effects with individual behaviors and metabolic factors is still lacking. Based on 176,874 participants from the most recent nationally representative surveillance on CKD and validated high spatial resolution (0.

Trends and the Role of Gene-Environment Interactions in Idiopathic Membranous Nephropathy in Northern China.

Introduction: Idiopathic membranous nephropathy (iMN) has become one of the most prevalent primary glomerular diseases, with a marked increase in prevalence over the past two decades in northern China. Fine particulate matter (PM2.5) is considered to be associated with this rising prevalence.

SARS-CoV-2-Induced Remission of Chemotherapy Resistance B-Cell Non-Hodgkin Lymphoma: A Case Report.

Introduction: Investigation on virus-host interaction may provide new clues for antitumor immunotherapy.

Case Presentation: In this case report, we describe an unusual case of B-cell non-Hodgkin lymphoma in an aged woman who recovered following SARS-COV-2 infection. We discuss the case and suggest that virus induced cross-reactivity against tumor account for the remission.

Thermo-mechanical coupling characteristics of the shearer's guiding shoe during the friction.

The reliability and longevity of the guiding shoe are crucial for the proper functioning of coal mining machines. The heavy wear of the sliding surface under thermal stress coupling is the primary factor influencing the service life of the guiding shoe. To reveal the heat flow distribution patterns and the thermo-stress coupling mechanisms of the guiding surface, a thermo-mechanical coupling model of the guiding shoe and the pin row is established.