Synergistic cation-anion regulation of active water within inner Helmholtz plane enables ultra-stable aqueous Zn ion batteries.

The issues related to corrosion, dendrite growth, and hydrogen evolution reaction (HER) of the Zn anode in aqueous environments have significantly obstructed the practical implementation of aqueous zinc ion batteries (AZIBs). Herein, the strategy of synergistically regulating the content of active water molecules located within the inner Helmholtz plane (IHP) by anions and cations is used to address the above-mentioned water-related issues of zinc metal anodes via using the 1-Ethyl-3-methylimidazolium tetrafluoroborate ionic liquid (IL) as an highly effective electrolyte additive. Theoretical computations and empirical outcomes show that the IL indirectly regulates IHP by tailoring solvation structure of Zn via anions and adsorbing cations on the surface of the zinc anode, directly and effectively reducing the content of chemically active HO molecules in IHP and thus significantly inhibiting the adverse reactions related to active HO molecules.

Construction of a Novel Secreted Protein Database and Identification of a New Adipokine CRELD2.

Background: Secreted proteins may become therapeutic targets, drugs and biomarkers for aging and disease. This study aimed to establish a novel secreted protein database for adipose tissue under access to food ad libitum (AL) and caloric restriction (CR), and verify a novel adipokine.

Methods: Twelve rat chips were used for whole-genome expression in various adipose tissues from AL and CR rats, followed by bioinformatics analysis and experiments in mice, rats, and humans as well as in obesity and diabetes models.

Multiview 2D/3D image registration in minimally invasive pelvic surgery navigation.

2D/3D medical image registration is crucial for image-guided surgery and medical research. Single-view methods often lack depth information, while multiview approaches typically rely on large-scale training datasets, which may not always be available in clinical scenarios. This paper explores the feasibility of multiview registration with insufficient data.

Fukui Function-Engineered Gel Electrolytes: Thermodynamic/Kinetic-Synergistic Regulation for Long-Cycling Zinc Metal Batteries.

While traditional gel electrolytes address critical issues such as electrolyte leakage and dendrite growth in zinc metal batteries (ZMBs), their intrinsic inability to suppress the competing hydrogen evolution reaction (HER) remains a fundamental limitation. Herein, a Fukui function-guided molecular engineering approach is proposed to develop a gel electrolyte (HG-3TP) with higher Gibbs free energy of HER (ΔG). The reduced electrophilic Fukui function inhibits Zn electron extraction while participating in Zn⁺ solvation to decrease free water activity.

The automatic pelvic screw corridor planning for intact pelvises based on deep learning deformable registration.

Percutaneous screw fixation technique in pelvic trauma surgery is an extremely challenging operation that typically requires a trial-and-error insertion process under the guidance of continuous intraoperative X-ray. This process can be simplified by utilizing surgical navigation systems. Understanding the complexity of the intraosseous pelvis corridor is essential for establishing the optimal screw corridor, which further facilitates preoperative planning and intraoperative application.

An electron-delocalized sp-N hybridized organic electrode enables sustainable and high-efficiency electrochemical ammonium removal.

Water scarcity emerges as a critical global challenge, with the purity of aquatic ecosystems intimately linked to ammonium concentrations. The removal of ammonium ions (NH ) is vital for mitigating ammonium contamination and promoting the sustainability of nitrogenous resources. Capacitive deionization (CDI) utilizing organic electrodes offers a promising electrochemical solution through a unique "ion coordination" mechanism; however, its efficacy is hindered by the presence of electrochemically inert units within the molecular framework for ion capture.

Longitudinal association between perceived economic stress and adolescents' depression in rural China: the mediating roles of hope trajectories.

Background: Family economic hardship is a risk factor for adolescents' depression. However, research on this topic is limited in its focus on objective economic conditions, and less is known about whether and how perceived economic stress is associated with adolescents' depression. This study explored the longitudinal relationship between perceived economic stress and depression and examined the extent to which heterogeneous developmental trajectories of hope explained the aforementioned relation in Chinese rural adolescents.

Long-Term Safety of "4-Hour" Hemoadsorption Combined with Hemodialysis in Maintenance Hemodialysis Patients: A Multicenter Prospective Cohort Study.

Introduction: Current guidelines recommend limiting hemoadsorption (HA) duration to 2 h during hemodialysis (HD) sessions due to theoretical concerns about adsorbent saturation and clotting risks. This multicenter prospective cohort study evaluated the long-term safety and efficacy of a novel "4Hs" protocol (4-h HA-HD with blood flow >250 mL/min).

Methods: 78 maintenance HD patients from four centers underwent 26 weeks of 4Hs therapy.

Exploring METRNL as a novel biomarker in sepsis: diagnostic potential and secretion mechanism.

Background: Sepsis is a life-threatening condition with a high mortality rate in intensive care unit (ICU). However, rapid and accurate diagnostic criteria are still lacking. This pilot study explored the role of METRNL as a novel biomarker for sepsis by focusing on its diagnostic potential and rapid secretion mechanism.

Association of 25-hydroxyvitamin D and physical activity with oral care needs among older U.S. adults.

Objectives: This study aimed to investigate the independent and combined association of serum 25-hydroxyvitamin D [25(OH)D] levels and physical activity on oral care needs in older United States (US) adults.

Methods: A cross-sectional study involving 6509 older adults aged 60 years and above data were included from the 2009-2018 National Health and Nutrition Examination Survey (NHANES). The main data for our study came from Questionnaires Data and Laboratory Data.

Identification of potential shared gene signatures between periodontitis and breast cancer by integrating bulk RNA-seq and scRNA-seq data.

Studies have shown that patients with periodontitis (PD) have an increased risk of breast cancer (BC). However, the exact mechanism remains to be further investigated. This study aimed to investigate the genes, pathways and immune cells that may interact with PD and BC.

Parent-Child Separation, Communication and the Developmental Trajectory of Depressive Symptoms in Chinese Adolescents.

Parent‒child separation as a result of parental migration is often associated with an increased risk of depressive symptoms in adolescents. However, little is known about how parent‒child separation affects changes in the development of depressive symptoms, particularly the protective factors (e.g.

Life cycle assessment of anaerobic digestion coupled co-pyrolysis for treatment of food waste.

In this study, the environmental impact of anaerobic digestion (AD) coupled co-pyrolysis (PY) to dispose of food waste (FW) was assessed. Four cases (mono AD, mono PY, AD coupled PY and AD coupled co-PY) were analyzed in comparison by life cycle assessment. The results showed that coupling technology was an environmentally viable technology compared with mono AD or PY.

Black phosphorus nanosheets activate tumor immunity of glioblastoma by modulating the expression of the immunosuppressive molecule PD-L1.

The tumor microenvironment in glioblastoma (GBM) is characterized by a pronounced immunosuppressive state, which significantly hampers tumor treatment and contributes to treatment resistance. While our previous research established that black phosphorus nanosheets (BPNS) inhibited glioblastoma cell migration and invasion, the impact of BPNS on the anti-tumor-associated immune mechanism remains unexplored. This study firstly investigated whether BPNS could modulate the tumor microenvironment through immunotherapy and elucidated the underlying mechanisms.

A Three-Tiered Golf Anode towards Ultralong-Life Zn-Mn Aqueous Batteries.

Zn-Mn aqueous batteries (ZMABs) are widely recognized as a promising candidate for large-scale energy storage due to their cost-effectiveness, high safety and environmental friendliness. However, the practical application of ZMABs is hindered by inherent electrical contact loss, hydrogen evolution and dendrite growth on traditional anodes. Here, a three-tiered golf anode with high conductivity is developed to simultaneously enhance the reversibility of Zn and Mn metals.

Developmental Trajectories of Intrinsic and Extrinsic Goals From Early to Late Adolescence and the Association with Internalizing and Externalizing Problems.

Although numerous studies have explored the causes and consequences of intrinsic and extrinsic life goals, the developmental trend of life goals during adolescence has not been well understood. To address this research gap, this study explored the developmental changes of the pursuit of intrinsic and extrinsic goals during early, middle, and late adolescence, and examined the relation between life goals and internalizing/externalizing problems from a developmental perspective. A total of 4703 Chinese adolescents from primary (N = 1819, 47.

A Dynamically Ion-Sieved Electrolyte towards Ultralong-Lifespan Zn-Ion Batteries.

The practical deployment of Zn-ion batteries faces challenges such as dendrite growth, side reactions and cathode dissolution in traditional electrolytes. Here, we develop a highly conductive and dynamically ion-sieved electrolyte to simultaneously enhance the Zn metal reversibility and suppress the cathode dissolution. The dynamic ion screen at the electrode/electrolyte interface is achieved by numerous pyrane rings with a radius of 3.

Dependable Automated Approach for Measuring the Retrograde Superior Ramus Screw Corridor in Pelvic Fracture Fixation.

Background: Precise measurement of the intraosseous corridor within the superior pubic ramus is essential for the accurate percutaneous placement of a retrograde superior ramus screw (SRS). However, conventional manual measurement methods are often subjective, leading to variations in results among observers. Our goal was to develop an automated and dependable method for determining the retrograde SRS corridor.

Regulation of Electron Delocalization Region in 2D Heteroligand-Based Copper-Organic Framework to Enhance Charge Storage.

The rechargeable aqueous ammonium ion battery shows great potential in low-cost energy storage system because of its long life and environmental friendliness. However, most inorganic host materials used in ammonium ion batteries are still limited by slow diffusion kinetics. Herein, it is identified that a 2D heteroligand-based copper-organic framework featuring numerous ammonium ion adsorption site in the π-conjugated periodic skeleton supplies multiple accessible redox-active sites for high-performance ammonium storage.

Ladder-Type Redox-Active Polymer Achieves Ultra-Stable and Fast Proton Storage in Aqueous Proton Batteries.

A ladder-type rigid-coplanar polymer with highly ordered molecular arrangement has been designed via a covalent cycloconjugation conformational strategy. Benefitting from the extended π-electron delocalization in the highly aromatic ladder-type polymeric backbone, the prepared polymer exhibits fast intra-chain charge transport along the polymeric chain, realizing extraordinary proton-storage capability in aqueous proton batteries.Affordable and safe aqueous proton batteries (APBs) with unique "Grotthuss mechanism," are very significant for advancing carbon neutrality initiatives.

Automatic diagnosis of pediatric supracondylar humerus fractures using radiomics-based machine learning.

The aim of this study was to construct a classification model for the automatic diagnosis of pediatric supracondylar humerus fractures using radiomics-based machine learning. We retrospectively collected elbow joint Radiographs of children aged 3 to 14 years and manually delineated regions of interest (ROI) using ITK-SNAP. Radiomics features were extracted using pyradiomics, a python-based feature extraction tool.

Does Parasympathetic Nervous System Activity Exacerbate Depressive Symptoms in College Students Who Experienced Parent-Child Separation? A Longitudinal Examination.

Childhood separation caused by parental migration increases the risk of suffering depressive symptoms among college students. However, most studies in this field have focused on environmental factors and largely ignored the role of physiological reactivity to stress (e.g.

Finite element analysis of modified Slongo's external fixation in the treatment of supracondylar humeral fractures in older children.

Older children over 8 years old are at higher risk of elbow joint stiffness after treatment of supracondylar humeral fractures. The objective of this study was to improve the Slongo's external fixation system for treating supracondylar humeral fractures in older children. This would be achieved by increasing fixation strength and providing a theoretical basis through finite element analysis and mechanical testing.