Measuring Managerial, Collegial, and Organizational Aspects Associated With Digital Health Competence in Healthcare Professionals: Validation of the Chinese Version of the DigiComInf Instrument.

Managerial, collegial, and organizational influences have been recognized as critical factors for developing digital health competence among healthcare professionals, but there is currently a lack of validated Chinese instruments to evaluate these factors. To culturally adapt and validate the Chinese version of the DigiComInf (aspects associated with digital health competence) instrument among Chinese healthcare professionals. The DigiComInf instrument was translated into Chinese following the established guidelines.

Validation of Chinese version of the familiar tools use test for assessing limb apraxia in stroke patients.

Objective: To validate the Familiar Tools Use Test (FTT) of the Diagnostic Instrument for Limb Apraxia-Short Version in Chinese stroke patients.

Methods: Participants were conveniently enrolled from a neurology ward in a tertiary hospital in Guangzhou, China, between April 2023 and September 2023. Internal consistency, test-retest reliability, inter-rater reliability, dimensionality, convergent validity, and divergent validity were examined.

The Chinese Version of the DigiHealthCom (Digital Health Competence) Instrument for Assessing Digital Health Competence of Health Care Professionals: Translation, Adaptation, and Validation Study.

Background: Digital health competence is increasingly recognized as a core competence for health care professionals. A comprehensive evaluation of knowledge, skills, performance, values, and attitudes necessary to adapt to evolving digital health technologies is essential. DigiHealthCom (Digital Health Competence) is a well-established instrument designed to assess digital health competence across diverse health care professionals.

Case report: Primary breast osteosarcoma: a case study and literature review.

Primary breast osteosarcoma (PBOS) is an extremely rare and poor prognostic malignancy. Here, we presented a 44-year-old female with a primary osteosarcoma of the breast (POB). Comprehensive imaging examinations conducted on the patient can be used to expand the imaging database for cases of breast osteosarcoma.

Niche and interspecific association of dominant zooplankton species near the Taishan coastal area in the South China Sea.

Marine zooplankton communities represent one of the most diverse and abundant species groups on earth. To investigate the ecological niche characteristics and interspecific interactions of marine zooplankton, and to elucidate their role in carbon deposition and biogeochemical cycling, we conducted a study on the zooplankton community near Taishan in the South China Sea between December 2015 and September 2016. Using niche breadth, niche overlap, the variance ratio method, chi-square tests, and linkage coefficients, we analyzed the interrelationships among the major zooplankton species.

Phytoplankton species composition as bioindicator in the largest fragmented channel of the Pearl River, China.

To test the serial discontinuity concept (SDC) predictions in a regulated river ecosystem, environmental parameters and phytoplankton community structure were determined in a subtropical river (China) which was regulated by 11 cascade dams. Our results showed that total phosphorus (TP) and silicate during the wet period in several dams supported the SDC predictions. Variations of phytoplankton species composition in several cascade dams, such as Datengxia (DTX) and Changzhou (CZ), also supported the SDC predictions.

Assessing limb apraxia after ischemic stroke: validation of the Chinese version of the diagnostic instrument for limb apraxia-short version (DILA-S) classic subtests.

Objective: This study aimed to translate and validate the Chinese version of the Diagnostic Instrument for Limb Apraxia-Short Version (DILA-S) classic subtests in Chinese patients after ischemic stroke.

Methods: The DILA-S was translated and adapted for use in Mandarin-speaking Chinese patients. Internal consistency, test-retest reliability, dimensionality, convergent validity, divergent validity, and concurrent validity were tested.

Intelligent Algorithm-Based Picture Archiving and Communication System of MRI Images and Radiology Information System-Based Medical Informatization.

Objective: The study aimed to explore the application value of picture archiving and communication system (PCAS) of MRI images based on radial basis function (RBF) neural network algorithm combined with the radiology information system (RIS).

Methods: 551 patients who required MRI examination in a hospital from May 2016 to May 2021 were selected as research subjects. Patients were divided into two groups according to their own wishes.

Leukamenin E Induces K8/18 Phosphorylation and Blocks the Assembly of Keratin Filament Networks Through ERK Activation.

Leukamenin E is a natural -kaurane diterpenoid isolated from (Hemsl) Hara that has been found to be a novel and potential keratin filament inhibitor, but its underlying mechanisms remain largely unknown. Here, we show that leukamenin E induces keratin filaments (KFs) depolymerization, largely independently of microfilament (MFs) and microtubules (MTs) in well-spread cells and inhibition of KFs assembly in spreading cells. These effects are accompanied by keratin phosphorylation at K8-Ser73/Ser431 and K18-Ser52 via the by extracellular signal-regulated kinases (ERK) pathway in primary liver carcinoma cells (PLC) and human umbilical vein endothelial cells (HUVECs).

Physical Mapping of Peroxidase Genes and Development of Functional Markers for on Bread Wheat Chromosome 7D.

Peroxidase (POD) activity in wheat ( L.) grain influences natural carotenoid pigment content and is associated with the color of flour, and processing and product quality. Here, we report the molecular characterization and physical mapping of POD genes in bread wheat.

Leukamenin E, an ent-kaurane diterpenoid, is a novel and potential keratin intermediate filament inhibitor.

Many ent-kaurane diterpenoids exhibit notable antitumor activity in vitro and in vivo, and some have been used as cancer therapeutic agents in China. In this study, we identified a novel molecular target of leukamenin E, an ent-kaurane diterpenoid, using an available whole-cell model in combination with immunofluorescence imaging and mass spectrometry (MS). The cytoskeleton-disrupting drugs cytochalasin B and colchicine caused the depolymerization of microfilaments and the collapse of microtubules and vimentin filaments, respectively, but had little effects on HepG2 and NCI-H1299 cells spreading as well as keratin filament (KF) reassembly, indicating that KFs are involved in cell spreading.