Publications by authors named "Jianjun Zuo"

This study evaluated the effects of maternal lysozyme oligomer (LYZ) supplementation on sow reproductive performance and piglet growth performance. Multiparous sows were randomly allocated to two groups: control and 0.1 % dietary LYZ.

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This study aimed at investigating the influences of pectic oligosaccharide (POS) on growth performance, organ indexes and intestinal health in broilers exposed to aflatoxin B (AFB). In vitro experiment was conducted to assess reactive oxygen species (ROS)-scavenging ability of POS. In vivo experiment was then implemented by allocating 320 one-day-old yellow-feathered broilers to 4 groups (8 replicates/group), according to a 2 × 2 factorial arrangement with POS addition (0 or 400 mg/kg) and AFB exposure (with or without) as the two factors.

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This study aimed to probe if a native probiotic Enterococcus faecalis TMBC 10513 could protect the growth and intestinal health of yellow-feathered broilers against avian pathogenic Escherichia coli (APEC) challenge. In vitro bacteriostasis of E. faecalis TMBC 10513 against APEC O1 was initially investigated.

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Xylooligosaccharide (XOS) is a typical prebiotic; however, whether it protects chickens from enterohemorrhagic (EHEC) challenge remains unknown. This study investigated the protective effects of XOS on the growth and gut health of EHEC-challenged broilers. A total of 270 1-day-old broilers were divided into three groups (nine replicates per group): negative control (were not challenged), positive control (EHEC-challenged from days 8 to 11), and XOS (EHEC-challenged broilers supplemented with 1.

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Introduction: This study evaluated the efficacy of substituting zinc oxide (ZnO) with varying levels of zinc lactate (ZnL) in weaned piglets.

Methods: A total of 128 Duroc × Landrace × Yorkshire (DLY) weaned piglets (7.31 ± 0.

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Background: Avian pathogenic Escherichia coli (APEC) threatens both poultry production and human health. Xylooligosaccharides (XOS) may suppress pathogenic bacteria through prebiotic actions. However, the influences of single degree of polymerization (DP) on the inhibition of APEC by XOS remain unknown.

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The importance of small bioactive peptides derived from pig spleen have been used to enhance immune responses and support intestinal health. However, there is a lack of information regarding the conformational relationship and their effects on immune function of pig spleen proteins (PSPs). The objective of this study was to prepare and assess the immunomodulatory characteristics of immunopeptides from PSP.

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Avian pathogenic Escherichia coli (APEC) represents a key pathogen severely threatening the poultry production, as well as food safety and public health. At present, the infection by APEC is hard to be prevented and controlled, because it possesses considerable virulence factors and high insensitivity to antibiotics. Short-chain fatty acids (SCFAs), the primary metabolites of intestinal probiotics, are considered to contribute to maintain intestinal health partially through inhibiting the activity of detrimental bacteria in gut.

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Weaning stress-induced diarrhea is a serious issue in pig production. This study aimed to evaluate the potential of glucose oxidase (GOD) as an antibiotic substitute to alleviate diarrhea and improve gut health in weaned piglets. According to a randomized complete block design, 250 piglets weaned around 21 d of age were allocated into 5 groups (5 replicates/group), which received a basal diet without or with supplemental 200 mg/kg antibiotic, 500, 1000 and 2000 U/kg GOD, respectively.

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Article Synopsis
  • This study investigated whether xylooligosaccharide (XOS) can impact the growth and antibiotic tolerance of a strain of avian pathogenic E. coli (APEC O78).
  • The findings indicated that XOS did not inhibit the growth of APEC O78 on standard growth medium, but did affect gene expression related to xylose metabolism and cell cycle regulation.
  • Overall, XOS did not directly kill APEC O78 but may function as an antimetabolite by mimicking xylose, potentially affecting antibiotic tolerance and metabolic activities.
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Introduction: Feeding bamboo powder is a kind of fiber raw material mainly composed of insoluble dietary fiber (IDF). In this study, IDF-based rice husk meal and feeding bamboo powder were used to compare the effects of bamboo fiber on fecal microflora and the performance of lactating sows and their offspring piglets.

Methods: Thirty healthy crossbred gilts (Yorkshire × Landrace) at day 105 of gestation were randomly allocated into three groups: CON, TRE1 supplemented with 2% BBF1 (feeding bamboo powder), and TRE2 supplemented with 2% BBF2 (99% feeding bamboo powder +1% bamboo fiber polymer material).

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Currently, there are plenty of histochemical methods to classify pig muscle fibers, which confused the naming and classification of muscle fibers. This study aims to analyze the difference and correlation of 6 different histochemical methods and select the most suitable method for muscle fiber classification at the molecular and histomological levels by in-situ RT-PCR and enzyme histochemical methods. Muscle fiber samples, including psoas (PM), semitendinosus (SM) and trapezius muscle (TM), were collected from Large Spotted (LS), Lantang (LT) and Landrace (LR) pigs at their market-ages (LS at 150 d, LT at 210 d, and LR at 150 d).

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  • The study investigated the effects of xylooligosaccharide (XOS), a prebiotic, on its ability to inhibit Salmonella Typhimurium colonization and improve gut health and growth in broiler chickens.
  • Results showed that XOS reduced the adhesion of S. Typhimurium to intestinal cells and lowered the expression of inflammatory markers and adhesion-related genes, indicating its protective role against bacterial infection.
  • Additionally, XOS supplementation in broilers challenged with S. Typhimurium improved gut morphology, increased weight gain, and reduced bacterial colonization in the intestines, highlighting its potential to enhance chicken health and growth performance.
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  • The study explored how N-acyl homoserine lactonase (AHLase) might reduce the harmful effects of a bacterial pathogen in broiler chicks and protect their intestines.
  • An in vitro test showed that AHLase can suppress the bacteria's ability to form biofilms, move, and stick to surfaces.
  • In vivo, AHLase improved growth performance in chicks challenged with the bacteria, reduced intestinal damage, and normalized levels of certain inflammatory markers.
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Introduction: This study was conducted to explore the effects of supplementary feeding of bamboo powder on the physical parameters of sows during the perinatal period of 7 days ± in parturition, including farrow duration, serum biochemical indexes, fecal physicochemical indexes, and microbial flora.

Methods: Thirty pregnant sows were randomly divided into three groups: the control group was fed a basal diet, TRE1 group and TRE2 group were fed a basal diet supplemented with 30 g d and 60 g d bamboo powder, respectively. Multiple parameters of sows and offspring piglets were determined.

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Article Synopsis
  • Serovar Typhimurium is a harmful Gram-negative bacterium that leads to gastrointestinal illnesses in humans and animals, with its infection process heavily relying on adhesins and invasins.
  • The study focused on the STM0306 protein, which was genetically mutated, revealing that its deletion significantly decreased the bacterium's ability to adhere and invade intestinal cells, alongside findings of its impact on cell inflammation.
  • Results indicated that STM0306 plays a crucial role in Typhimurium's pathogenicity by activating inflammatory responses in host cells and contributing to its overall virulence in infected mice.
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MicroRNAs are one of the key determinants of muscle fibre development and phenotype in mammals. The preliminary experiment implied that microRNA-27a (miR-27a) might involve in regulation of muscle fibre type composition of pigs. Thereby, the present study aimed to confirm the regulatory effect of miR-27a on porcine type I muscle fibre-encoding gene (myosin heavy chain gene 7, MYH7) expression and its related mechanism.

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Background: Salmonella Typhimurium challenge causes a huge detriment to chicken production. N-acyl homoserine lactonase (AHLase), a quorum quenching enzyme, potentially inhibits the growth and virulence of Gram-negative bacteria. However, it is unknown whether AHLase can protect chickens against S.

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  • The study examines how exogenous catalase (CAT) affects oxidative stress and gut microbiota in chickens exposed to deoxynivalenol (DON).
  • The experiment involved 144 one-day-old broilers divided into three groups: a control group, a DON group, and a group receiving both DON and CAT (DONC).
  • Results showed that CAT mitigated liver enlargement and oxidative damage caused by DON, improved intestinal health, and altered gut microbiota by increasing beneficial bacteria and decreasing harmful ones.
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Glucose oxidase (GOD) could benefit intestinal health and growth performance in animals. However, it is unknown whether GOD can protect piglets against bacterial challenge. This study aimed to evaluate the protective effects of GOD on growth performance, clinical symptoms, serum parameters, and intestinal health in piglets challenged by enterotoxigenic (ETEC).

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Objective: This study was aimed to explore the efficacy of combination of endo-xylanase (Xyn) and xylan-debranching enzymes (arabinofuranosidase, Afd and feruloyl esterase, FE) in improving utilization of bran in piglet diet.

Methods: In vitro experiments were firstly conducted to examine the enzymological properties of Xyn, Afd, and FE, concurrent with their effect on degradation of arabinoxylan (Abx) in bran. In vivo experiment was then implemented by allocating two hundred and seventy 35-d-old postweaning piglets into 3 groups (6 replicates/group), which received bran-containing diet supplemented with Xyn (1,600 U/kg) or its combination with Afd (0.

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Adding insoluble fiber to diet of broilers has been reported to improve intestinal health and promote growth performance. Bamboo powder is a cheap raw material with rich insoluble fiber. This study aims to explore the effects of feeding micronized bamboo powder (MBP) on growth performance, serum biochemical indexes, intestinal microflora, and metabolism of broilers.

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  • Typhimurium is a pathogen that causes gastrointestinal diseases in humans and animals, and the role of the heat shock protein HtpG in its infection was previously unclear.
  • The study found that mutations in HtpG led to a decrease in several key pathways for Typhimurium, resulting in reduced motility, biofilm formation, and the ability to induce inflammation.
  • Additionally, HtpG recombinant protein was shown to enhance Typhimurium proliferation in host cells, highlighting its significant role in the infection process.
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This study investigated the effects of different amounts of wheat aleurone (WA) (0, 15%, 30%) inclusion in gestation diets on the reproductive performance, postprandial satiety, stress status and stereotypic behaviors of sows. A total of 84 Landrace × Yorkshire sows (parity 4.87 ± 1.

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Guar gum-derived galactomannan (GGGM) has been widely used in the food industry for a long time and its adverse impacts have been scarcely reported. Galactomannan is considered to have a structure similar to the surface components of certain pathogens, and the present study was thus conducted to investigate if oral administration of GGGM could cause physiological effects that were hypothesized to be related to intestinal inflammatory responses. The results showed that oral administration of GGGM resulted in compromises on growth performance, an increase of the relative weight of spleen and epididymal fat, and an elevation of the α1-acid glycoprotein content in both serum and livers of mice.

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