Dependability of Large Language Models in Cardiovascular Medicine: A Scoping Review.

Background: The adoption of large language models (LLMs) in both clinical and consumer healthcare settings has surged exponentially. However, there remains limited evidence on their reliability and impact in cardiovascular practice.

Objectives: This scoping review was designed to consolidate the existing biomedical literature on applicability, reliability, and quality improvement strategies for the integration of LLMs into the cardiovascular domain.

Intraoperative lactate level correlated with the length of hospital stay in patients with intraoperative hypothermia.

This study aims to explore potential biomarkers correlated with the clinical outcome only in patients with intraoperative hypothermia undergoing cardiac surgery. The clinical data of patients with or without intraoperative hypothermia, and 8 blood indicators both in preoperative and intraoperative periods, were obtained from the Medical Information Mart for Intensive Care-IV database. The associations of indicators with the length of hospital stay (LOS) were explored in non-hypothermia and hypothermia groups, respectively.

Incidence, risk factors and outcomes for post-hepatectomy portal vein thrombosis: A retrospective study.

Background: Post-hepatectomy portal vein thrombosis (PH-PVT) is a life-threatening complication; however, the available literature on this topic is limited.

Aim: To examine the incidence, risk factors, and outcomes associated with PH-PVT.

Methods: Medical records of patients who underwent hepatic resection for various diseases between February 2014 and December 2023 at Beijing Tsinghua Changgung Hospital affiliated with Tsinghua University (Beijing, China) were retrospectively reviewed.

Machine learning model-based prediction of postpancreatectomy acute pancreatitis following pancreaticoduodenectomy: A retrospective cohort study.

Background: The International Study Group of Pancreatic Surgery has established the definition and grading system for postpancreatectomy acute pancreatitis (PPAP). There are no established machine learning models for predicting PPAP following pancreaticoduodenectomy (PD).

Aim: To explore the predictive model of PPAP, and test its predictive efficacy to guide the clinical work.

Development of a complex intervention to prevent complications in patients recovering at home after transcatheter aortic valve replacement by optimizing home-based cardiac rehabilitation processes: a Delphi study.

Objectives: This study aimed to systematically develop a nurse-led complex intervention to enhance the quality of and adherence to home-based cardiac rehabilitation (HBCR) care for patients who have undergone transcatheter aortic valve replacement (TAVR). The intervention integrated stakeholder perspectives, expert insights, empirical evidence, and theoretical frameworks.

Methods: We initially searched for initial cardiac rehabilitation strategies based on the "Behavior Change Wheel" model and literature review.

The effectiveness of a nurse-led home-based cardiac rehabilitation based on instant information intervention in the prognosis of patients with TAVR: A randomized controlled trial protocol.

Background: Patients with poor prognosis after TAVR surgery require high-quality cardiac rehabilitation. Digital home-based rehabilitation based on real-time information intervention can improve outcomes. However, the parameters of the text message intervention, such as text message content, intervention duration, text message frequency, and other parameters, may vary.

Prognostic models for patients suffering a heart failure with a preserved ejection fraction: a systematic review.

The purpose of this study was to systematically review the development, performance, and applicability of prognostic models developed for predicting poor events in patients with heart failure with preserved ejection fraction (HFpEF). Databases including Embase, PubMed, Web of Science Core Collection, the Cochrane Library, China National Knowledge Infrastructure, Wan Fang, Wei Pu, and China Biological Medicine were queried from their respective dates of inception to 1 June 2023, to examine multivariate models for prognostic prediction in HFpEF. Both forward and backward citations of all studies were included in our analysis.

Can virtual reality have effects on cardiac rehabilitation? An overview of systematic reviews.

Objective: This paper aims to provide a review of the use of virtual reality in cardiac rehabilitation.

Background: Can virtual reality technology improve outcomes in patients with cardiovascular disease? The question is still open.

Design: Systematic review and meta-analyses.

Boron-Assisted Selective Citrulline Modification under Mild Conditions.

Protein citrullination is one type of protein post-translational modification. Previous methods entail the use of a strongly acidic condition (pH <1), which impedes its exploration under physiological and pathological conditions. Here, we developed a biocompatible method based on -boron-assisted citrulline modification.

Analysis of Influencing Factors of Unplanned Readmission in Patients With Acute Coronary Syndrome Within 30 Days After PCI.

Objective: The purpose of this study is to identify the influencing factors of unplanned readmission in patients with the acute coronary syndrome (ACS) within 30 days after percutaneous coronary intervention (PCI).

Methods: From November 1, 2018, to October 31, 2019, the clinical data of 1277 patients with acute coronary syndrome and percutaneous coronary intervention retrospectively were collected. After screening by exclusion and rejection criteria, a total of 936 patients finally entered the study.

Garcinia Biflavonoid 1 Improves Lipid Metabolism in HepG2 Cells via Regulating PPARα.

Garcinia biflavonoid 1 (GB1) is one of the active chemical components of and is reported to be capable of reducing the intracellular lipid deposition, which is the most significant characteristic of non-alcoholic fatty liver disease. However, its bioactive mechanism remains elusive. In the current study, the lipid deposition was induced in HepG2 cells by exposure to oleic acid and palmitic acid (OA&PA), then the effect of GB1 on lipid metabolism and oxidative stress and the role of regulating PPARα in these cells was investigated.

MOF-derived nitrogen-doped core-shell hierarchical porous carbon confining selenium for advanced lithium-selenium batteries.

The lithium-selenium (Li-Se) battery has attracted growing interest recently due to its high energy density and theoretical capacity. However, the shuttle effect and volume change during cycling severely hinder its further application. In this work, we report a metal-organic framework (MOF)-derived nitrogen-doped core-shell hierarchical porous carbon (N-CSHPC) with interconnected meso/micropores to effectively confine Se for high-performance Li-Se batteries.

Three Constituents of Seeds Regulate Expression of Th17-Relevant Cytokines and Ameliorate TPA-Induced Psoriasis-Like Skin Lesions in Mice.

As a folk medicine, L. is used effectively to treat inflammatory conditions and skin diseases. However, its mechanism of action is not well understood, limiting its medical use.

Hierarchically Dual-Mesoporous TiO Microspheres for Enhanced Photocatalytic Properties and Lithium Storage.

Hierarchically dual-mesoporous TiO microspheres have been synthesized by a solvothermal process in the presence of 1-butyl-3-methylimidazolium tetrafluoroborate ([BMIm][BF ]) and diethylenetriamine (DETA) as co-templates. Secondary mesostructured defects in the hierarchical TiO microspheres produce oxygen vacancies, which not only significantly enhance photocatalytic activity in the degradation of methylene blue (1.7 times that with P25) and acetone (2.

Epidemiological Features of Nontraumatic Spontaneous Subarachnoid Hemorrhage in China: A Nationwide Hospital-based Multicenter Study.

Background: Nontraumatic spontaneous subarachnoid hemorrhage (SAH) is associated with a high mortality. This study was conducted to investigate the epidemiological features of nontraumatic spontaneous SAH in China.

Methods: From January 2006 to December 2008, the clinical data of patients with nontraumatic SAH from 32 major neurosurgical centers of China were evaluated.

[Analytical studies on flavonoids constituents in Apocynum venetom leaves by UPLC-Q-TOF-MS].

Objective: To establish an ultra-performance liquid chromatography quadrupole-time-of-flight mass spectrometric (UPLC-Q-TOF-MS) method for analyzing the flavonoids constituents in Apocynum venetom leaves.

Methods: The analysis was performed on an Alltima C18 analytical column with a gradient solvent system of acetonitrile-1.0% acetic acid at the flow rate of 0.

[Study on HPCE-DAD fingerprint of Salviae Miltiorrhizae Radix et Rhizoma].

Objective: To establish the analytical method for the fingerprint of Salviae Miltiorrhizae Radix et Rhizoma by HPCE-DAD and estimate its quality.

Methods: Salviae Miltiorrhizae Radix et Rhizoma were analyzed and the chromatographic fingerprint were determined by HPCE-DAD. The data were analysed by fuzzy cluster and fingerprint similarity evaluation software was used to compare the similarity of samples.

Emotion and cognitive function assessment of patients with central neurocytoma resection through transcortical frontal approach: a 5-year postoperative follow-up study.

Background: Central neurocytoma accounts for 0.1% of primary brain tumor that often occurs in young adults. Surgery is the main treatment for central neurocytoma and the rate of 5-year survival reaches up to over 90%.

Polymorphisms of VEGFA gene and susceptibility to hemorrhage risk of brain arteriovenous malformations in a Chinese population.

Aim: To evaluate the influence of the vascular endothelial growth factor A (VEGFA) polymorphisms on risk of presentation with intracerebral hemorrhage (ICH).

Methods: Nine selected VEGFA single-nucleotide polymorphisms (SNPs) were genotyped in 311 patients with brain arteriovenous malformations (BAVM) in a Chinese population. Associations between individual SNPs/haplotypes and the hemorrhage risk of BAVMs were evaluated using logistic regression analysis.

Two novel mutations of the MYBPC3 gene identified in Chinese families with hypertrophic cardiomyopathy.

Background: Hypertrophic cardiomyopathy (HCM) is one of the most common genetic cardiovascular disorders. Mutations in the MYBPC3 gene are one of the most frequent genetic causes of HCM.

Objectives: To screen MYBPC3 gene mutations in Chinese patients with HCM, and analyze the correlation between the genotype and the phenotype.

[Studies on HPCE fingerprint of Folium Apocyni Veneti].

Objective: To establish the analytical method for the fingerprint of Folium Apocyni Veneti by HPCE and estimate the quality of Folium Apocyni Veneti from different habitats.

Methods: Folium Apocyni Veneti from different habitats were analyzed and the chromatographic fingerprint were determined by HPCE. The data were analysed by Fuzzy Cluster and Fingerprint Similarity Evaluation Software to compare the similarity of samples.

[Study on the dynamic change of essential components in Folium Apocyni Veneti].

Objective: To determine the dynamic change of essential components in Folium Apocyni Veneti, and provide scientific basis for determining the best collecting time.

Methods: The essential components of Folium Apocyni Veneti from different harvesting time were analyzed by HSGC-MS. The relative content of the components were determined with peak area normalization method, and the dynamic changes of 7 main bioactive components were determined.

[Defibrillation efficacy of a newly developed automated external defibrillator in a swine ventricular tachycardia/fibrillation model].

Objective: The aim of this study was to evaluate the recognition and defibrillation efficiency of a newly developed automated external defibrillator (AED).

Method: Ventricular tachycardia (VT)/ventricular fibrillation (VF) was induced by alternating current (50 Hz) through an electrode placed on apex of right ventricle in 23 anesthetized swine and recorded, recognized and defibrillated by a newly developed AED.

Results: A total of 96 VF was induced and 145 defibrillations were recorded.