Severity: Warning
Message: file_get_contents(https://...@gmail.com&api_key=61f08fa0b96a73de8c900d749fcb997acc09&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 197
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 197
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 271
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3165
Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
Line: 597
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 511
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 317
Function: require_once
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Objective: To determine the dynamic change of essential components in Folium Apocyni Veneti, and provide scientific basis for determining the best collecting time.
Methods: The essential components of Folium Apocyni Veneti from different harvesting time were analyzed by HSGC-MS. The relative content of the components were determined with peak area normalization method, and the dynamic changes of 7 main bioactive components were determined.
Results: 39 constituents were separated and 38 compounds were identified. There were 21 co-containing compounds in Folium Apocyni Veneti from different harvesting time, the accumulation of which showed a regular pattern.
Conclusion: The main essential components in Folium Apocyni Veneti are the highest in the traditional harvesting time.
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