Edge-sharing bi-octahedral diruthenium(IV,IV) compounds containing Ru-Ru bonds chelated and bridged by two carbonate and two oxo groups.

From paddle-wheel starting material NaRu(CO)·6HO, a family of edge-sharing bi-octahedral (ESBO) diruthenium(IV,IV) compounds formulated as RuO(CO)(HO)L·HO [L = piperazine (1) or 2-methylpiperazine (2), = 4, and L = 2,2-dimethylpiperazine (3), = 12] and RuO(CO)(OH){M(HO)}·HO [M = Mg (4), = 4, and Ni (5), = 2] were prepared and structurally characterized. The Ru dimer is chelated and bridged by two CO and two μ-O in a manner, and the Ru-Ru distances fall in the range 2.3808(6)-2.

A family of edge-sharing bi-octahedral diruthenium(III,III) compounds containing Ru-Ru single bonds.

From paddlewheel starting reactants Ru(R'CO), a family of edge-sharing bi-octahedral (ESBO) diruthenium(III,III) compounds has been prepared, formulated as Ru(μ-OCR')(μ-OR)(η-L) (1-10) [R' = CH, R = CH, L = acac (1), tfac (2); R' = CH, R = CHCH, L = hfac (3); R' = CHCH, R = CH, L = acac (4), tfac (5); R' = CHCH, R = CHCH, L = hfac (6); R' = CHCl, R = CH, L = tfac (7); R' = CHCl, R = CHCH, L = hfac (8); R' = CH, R = CH, L = tfac (9); and R' = H, R = CH, L = acac (10); here, acac, tfac and hfac represent acetylacetone, trifluoroacetylacetone and hexafluoroacetylacetone, respectively]. Compounds 1-10 have a similar ESBO coordination geometry of the Ru(μ-OCR')(μ-OR)Ru core with a Ru-Ru center chelated and bridged by two μ-OCR' and two μ-OR in a manner, and each Ru center is also coordinated with a η-L bidentate ligand. The Ru-Ru distances fall in the range of 2.

Homo-valent diruthenium(II,II) carbonates Na[Ru(CO)]·10HO: synthesis, structure, properties, and calculation.

Homo-valent diruthenium(II,II) carbonates have been underexplored hitherto. This paper reports the synthesis and crystal structure of a diruthenium(II,II) compound, NaRu(CO)·10HO (1). It has a two-dimensional structure in which the paddle-wheel diruthenium units of Ru(CO) are cross-linked through the carbonate groups.

Silencing of circ-NT5C2 retards the progression of IL-1β-induced osteoarthritis in an in vitro cell model by targeting the miR-142-5p/NAMPT axis.

Osteoarthritis (OA) is a degenerative disease that occurs mostly in the elderly, and its specific pathogenesis is still unknown, but recent studies have found that circular RNA generally display aberrant expression in OA. Our study explored the expression characteristics and mechanism of action of circ-NT5C2 in OA. Circ-NT5C2, microRNA-142-5p (miR-142-5p), and nicotinamide phosphoribosyltransferase (NAMPT) mRNA levels were measured using RT-qPCR.

Maternal exposure to cooking oil fumes during pregnancy and autistic-like behaviors in Chinese preschoolers.

There is growing evidence that cooking oil fumes (COFs) are harmful indoor air pollutants. However, there is a dearth of research investigating whether maternal COFs exposure during pregnancy may affect children's autistic-like behaviors in China. This study aimed to explore this association, and examine the effects of different cooking fuels and ventilation methods used by mothers on the presence of autistic-like behaviors.

Association between environmental tobacco smoke exposure in early life and autistic-like behaviors in Chinese preschoolers.

Objective: Few studies have evaluated the association between children's exposure to environmental tobacco smoke (ETS) in early life (during pregnancy, from birth to one year and from one to three years) and autistic-like behaviors. This study aimed to explore this association.

Methods: This cross-sectional study analyzed data collected in 2017 as part of the Longhua Child Cohort Study.

Association between prenatal exposure to indoor air pollution and autistic-like behaviors among preschool children.

Indoor air pollution is a recognized risk factor for a range of negative health outcomes. This study aimed to investigate the association between maternal prenatal exposure to indoor air pollution and the presence of autistic-like behaviors among preschool children. Data were obtained from the Longhua Child Cohort Study in 2017, in which we enrolled a total of 65 317 preschool children.

Interlayer hydrogen bonding directed magnetic properties for a different number of water-intercalated structural heterometallic phosphates based on paddlewheel units Ru(PO).

Layered heterometallic phosphates {Mn(H2O)4}2Mn(H2O)2Ru2(PO4)4(H2O)2 (1) with a new topology were constructed from Ru2(PO4)46- and Mn2+ in the presence of anions as assisting reactants whose alkaline strength plays a key role in directing a different number of lattice water-intercalated structures. In the presence of CO32- and SO42- as assisting reactants, the assembling reaction in the aqueous solution at room temperature results in compounds 1·10H2O and 1·4H2O, respectively. Single-crystal X-ray diffraction analysis reveals that compounds 1·10H2O and 1·4H2O crystallize in orthorhombic space group Pbca and monoclinic space group P21/c, respectively.

Associations between Prenatal Education, Breastfeeding and Autistic-Like Behaviors in Pre-Schoolers.

This study aimed to investigate the association between prenatal education and autistic-like behaviors of preschoolers as well as the mediating role of breastfeeding in their associations. A cross-sectional study via a structured questionnaire was conducted with 67,578 preschool children and parents from Longhua District of Shenzhen, China. Hierarchical logistic regression models were performed to explore the associations between maternal participation in prenatal education and autistic-like behaviors in preschoolers, as well as the mediating effect of breastfeeding in the associations.

Chromous carbonates containing a square-grid layer of {Cr(CO)} based on a dichromium(II,II) paddlewheel core.

Polymeric coordination compounds based on Cr2n+ paddle-wheel building blocks with non-carboxylate O,O-donor ligands chelating and bridging the Cr-Cr centers have been underexplored hitherto. This paper reports the synthesis and crystal structure of a new homo-valent chromium(ii,ii) compound, Na3HCr2(CO3)4·10H2O (1). It has a two-dimensional structure in which the paddlewheel chromium(ii,ii) units of Cr2(CO3)44- are cross-linked through the carbonate groups.

Grinding enhances the magnetic hardness of heterometallic diruthenium(ii,iii) carbonates with a kagome lattice structure.

The assembly of paddle-wheel Ru building units affords a new trimetallic carbonate, CsCd(HO)[{Cd(HO)}{Ru(CO)}]·10HO (1), that contains structurally near-perfect kagome layers, {Ru(CO)}, linked by octahedral Cd(HO) into a nanoscale kagome network exhibiting ferromagnetic ordering below 3.5 K. The investigation of influences of the grinding method on the crystal samples of compound 1 reveals that the coercivity increases from ∼2.

Enhancing magnetic hardness by sonication assisted synthesis of heterometallic carbonato spin-glass Na[Ni(HO)Ru(CO)]·3HO.

Control of magnetic performances of molecular magnets is essential but few efforts have been documented. A green and efficient sonication assisted synthesis of a new heterometallic diruthenium(ii,iii) carbonate, Na[Ni(H2O)4Ru2(CO3)4]·3H2O (1), was carried out by self-assembling in aqueous solution. Compound 1 exhibits spin-glass behavior below ∼5.

Prescribing errors in electronic prescriptions for outpatients intercepted by pharmacists and the impact of prescribing workload on error rate in a Chinese tertiary-care women and children's hospital.

Background: Prescribing errors may, influenced by some risk factors, cause adverse drug events. Most studies in this field focus on errors in prescriptions for hospital inpatients, with only a few on those for outpatients. Our study aimed to explore the incidence of prescribing errors in electronic prescriptions and illustrate the trend of prescribing workload and error rate over time.

Complete duodenal obstruction induced by groove pancreatitis: A case report.

Background: Groove pancreatitis (GP) is a type of chronic pancreatitis occurring in an anatomic area between the duodenum, head of the pancreas, and common bile duct. Duodenal obstruction is always caused by malignant pancreatic diseases, such as pancreatic head carcinoma, while is rarely induced by benign pancreatic diseases, such as pancreatitis.

Case Summary: A 39-year-old man presented with a 1-mo history of upper abdominal discomfort.

Alkali counterions tune diruthenium(iii,iii)-based ferrimagnetic chain structured antiferromagnets exhibiting step-like hysteresis loops.

The synthesis of antiferromagnets (AFMs) has attracted extensive attention in the area of magnetic devices, such as spintronics and memory devices. Following our initial work on the employment of the homo-valent diruthenium(iii,iii) paddle wheel species with high spin states (S = 2) as building blocks and active components for the construction of molecule-based magnetic materials, the reaction of mixed-valent diruthenium(ii,iii) phosphates Ru(HPO)(HPO)(HO)·2HO (1) with HO, Cu and ACl (A = K, Rb and Cs) in aqueous solution led to the formation of heterometallic copper diruthenium(iii,iii) phosphates A[Cu(HO)Ru(HPO)(PO)(HO)]·nHO [A = K (2); A = Rb and n = 2 (3); A = Cs and n = 3 (4)]. The compounds consist of chain structures in which each octahedral environment of Cu(HO) bonds to two [Ru(HPO)(PO)] units in a trans manner, forming a ferrimagnetic negative chain {Cu(HO)Ru(HPO)(PO)(HO)}, exhibiting anomalous magnetic properties.

[Substitution efficiency of agro-chemical input intensity and its influence factors].

We examined the substitution efficiency of agro-chemical input intensity from 2000 to 2016 in China by employing SE-DEA model and Gini coefficient, and analyzed the driving factors of substitution efficiency with Tobit model. The results showed that the comprehensive efficiency and the scale efficiency of substitution of agro-chemical input intensity displayed the trend of "N-shaped", while the pure technical efficiency was enhanced with some fluctuations. The regional diffe-rences of substitution efficiency were obvious, with the eastern region relying more heavily on the input scale of substitution factors.

Vancomycin-induced severe thrombocytopenia in a young infant.

Vancomycin is a first-line drug for treating methicillin-resistant Staphylococcus aureus. Thrombocytopenia is a rare adverse reaction to vancomycin treatment, and there are no reports of vancomycin-induced thrombocytopenia (VIT) in infants. We describe the case of a 3-month-old girl who was diagnosed with purulent meningitis.

Identification of MGMT promoter methylation sites correlating with gene expression and IDH1 mutation in gliomas.

O-methylguanine-DNA methyltransferase (MGMT) gene promoter methylation was reported to be an independent prognostic and predictive factor in glioma patients who received temozolomide treatment. However, the predictive value of MGMT methylation was recently questioned by several large clinical studies. The purpose of this study is to identify MGMT gene promoter CpG sites or region whose methylation were closely correlated with its gene expression to elucidate this contradictory clinical observations.

Echinocystic acid inhibits RANKL-induced osteoclastogenesis by regulating NF-κB and ERK signaling pathways.

Receptor activator of nuclear factor-κB ligand (RANKL) is a key factor in the differentiation and activation of osteoclasts. Echinocystic acid (EA), a pentacyclic triterpene isolated from the fruits of Gleditsia sinensis Lam, was reported to prevent reduction of bone mass and strength and improve the cancellous bone structure and biochemical properties in ovariectomy rats. However, the molecular mechanism of EA on the osteoclast formation has not been reported.

Electroacupuncture promotes the recovery of motor neuron function in the anterior horn of the injured spinal cord.

Acupuncture has been shown to lessen the inflammatory reaction after acute spinal cord injury and reduce secondary injury. However, the mechanism of action remains unclear. In this study, a rat model of spinal cord injury was established by compressing the T8-9 segments using a modified Nystrom method.

Chlorine and temperature directed self-assembly of Mg-Ru2(ii,iii) carbonates and particle size dependent magnetic properties.

A series of heterometallic magnesium diruthenium(ii,iii) carbonates, namely K{Mg(H2O)6}2[Ru2(CO3)4Cl2]·4H2O (1), K2[{Mg(H2O)4}2Ru2(CO3)4(H2O)Cl]Cl2·2H2O (2), K[Mg(H2O)5Ru2(CO3)4]·5H2O (3) and K[Mg(H2O)4Ru2(CO3)4]·H2O (4), were synthesized from the reaction of Ru2(CO3)4(3-) and Mg(2+) in aqueous solution. Compound 1 is composed of ionic crystals with the Ru2(CO3)4Cl2(5-) : Mg(H2O)6(2+) : K(+) ratio of 1 : 2 : 1. Compound 2 consists of two dimensional layer structures, in which each octahedral environment Mg(H2O)4(2+) bonds to two [Ru2(CO3)4(H2O)Cl](4-) units in a cis manner forming a neutral square-grid layer {Mg(H2O)4Ru2(CO3)4(H2O)Cl}n.

A huge adenosquamous carcinoma of the pancreas with sarcomatoid change: an unusual case report.

Adenosquamous carcinoma rarely occurs in the pancreas, and is characterized by the presence of cellular components from both duct adenocarcinoma and squamous carcinoma. Here, we describe a rare case of pancreatic adenosquamous carcinoma with sarcomatous change. Immunohistochemistry showed that the sarcomatous lesion lost the epithelial marker and aberrantly expressed of acquired mesenchymal markers, which indicated that this special histological phenotype may be attributed to epithelial-mesenchymal transition.

Isomeric chain structures of {[Mn(H₂O)₄]₂Ru₂(CO₃)₄Br₂}n(n-): syntheses, structural diversity and magnetic properties.

The self-assembly of Ru2(CO3)4(3-) paddle-wheel precursors and Mn(2+) ions in aqueous solution yields various carbonate complexes. With appropriate selection of the synthetic conditions, we are able to intentionally tune the composition and structure of Mn-Ru2-carbonate assemblies to form infinite chain structural complexes, e.g.

Experimental single qubit quantum secret sharing in a fiber network configuration.

We present a robust single-photon quantum secret sharing (QSS) scheme with phase encoding in three-party implementations and a design way of more parties over a 50 km single-mode fiber network using a single QSS protocol. This scheme automatically provides perfect compensation for birefringence. A high visibility of 99.

Incorporation of M(H2O)6(2+) between layers {M(H2O)2Ru2(CO3)4Cl2}n(2n-) (M = Zn, Mn): syntheses, structures and magnetic properties.

Isostructural heterometallic diruthenium carbonates KM(H2O)6[M(H2O)2Ru2(CO3)4Cl2]·4H2O [M = Zn (1) and Mn (2)] were synthesized from the reaction of the precursors [Ru2(CO3)4Cl2](5-) and transitional metal ions in aqueous solution. Complexes 1 and 2 show layered structures in which Ru2(II,III) units are linked by four octahedral environment M(H2O)2(2+) ions in a cross fashion and vice versa giving a negative bimetallic square grid layer {M(H2O)2Ru2(CO3)4Cl2}n(3n-). M(H2O)6(2+) ions, linked by K(+) forming zigzag chain {KM(H2O)6}n(3+), are located in the void spaces between the layers.