Lattice-Engineered Lanthanide Nanocrystals with Tunable Near-Infrared-IIb Lifetime.

Lattice engineering in lanthanide nanocrystals (LnNCs) is fundamental for tailoring their versatile optical properties, yet it remains underexplored in manipulating the downconversion characteristics. Here, we engineer the lattices from distorted to strain-graded in LnNCs by CaF deposition on vacancy-controlled β-NaGdF:Yb,A (A = Tm/Er, x = 0.5, 0.

Bismuth-Doped AgTe Colloidal Quantum Dots for High-Performance Shortwave-Infrared Photodetectors.

Recently, silver telluride (AgTe) colloidal quantum dots (QDs) have garnered significant attention in short-wave-infrared (SWIR) photodetection owing to their strong SWIR responsivity and environmental benignity. However, the SWIR AgTe QDs often suffer from their high defect density, leading to an unsatisfactory utilization efficiency of the photogenerated charge carriers. To address this challenge, here, we have developed bismuth-doped AgTe (Bi:AgTe) QDs via a hot-injection doping method.

Design of high-energy X-ray conversion target based on linear electron accelerator.

High-energy X-rays can be employed to inspect fuel elements, even weld seams, cracks, and internal structural deformations of the components due to their density-sensitive characteristics and strong penetration capabilities. The quality of these X-rays is determined by various factors such as the X-ray conversion target, the cooling system for the conversion target, and the filter type, thereby influencing the detection accuracy. This study was conducted using an electron linear accelerator with an energy of 10 MeV and an average current of 150 μA.

Diagnostic and therapeutic review of a rare gastric inflammatory fibroid polyps case with distinctive features: A case report.

Background: Inflammatory fibroid polyps (IFPs) are generally considered as benign and relatively rare mesenchymal gastrointestinal tract tumors. IFPs can occur in any part of the gastrointestinal tract but are most prevalent in the stomach, particularly in the gastric antrum. With a low incidence in clinical practice and a lack of distinct endoscopic features, the preoperative diagnosis rate of IFP is disappointingly low, often leading to missed diagnoses or misdiagnoses.

Dipole-Dipole Interaction-Induced Direct Self-Assembly of AgS Quantum Dots into Supercrystals in Solution.

Long-range ordered supercrystals (SCs) built up by colloidal nanocrystals (NCs) represent a class of novel metamaterials with unique collective properties. While great attention has been paid to the ligand-controlled assembly of NCs, the contribution of the inorganic core is considered limited because of the weak core-core interactions. Here, we report the spontaneous assembly of AgS quantum dots (QDs) into three-dimensional SCs in solution, driven by pronounced dipole-dipole interactions.

Ligand-Solvent Library Design for Tailoring Interparticle Interactions in Colloidal Nanocrystals.

This study explores the critical role of nonpolar ligand-solvent systems in modulating interparticle interactions in colloidal nanocrystals, profoundly affecting colloidal stability and enabling precision self-assembly. A library of 28 ligands with diverse molecular fragments─double bonds, branched chains, benzene rings, and naphthalene rings─and four solvents was developed to investigate how fragment types and positions affect ligand ordering and interparticle attraction. Explicit solvent simulations with enhanced sampling techniques reveal that fragments near the headgroup or midsection disrupt ligand ordering and weaken interparticle attraction, whereas terminal placement fosters ordered ligand packing and enhances attraction.

Tumor Microenvironment-Responsive Nano-Immunomodulators for Enhancing Chimeric Antigen Receptor-T Cell Therapy in Lung Cancer.

Chimeric antigen receptor (CAR)-T cells have shown unparalleled efficacy in treating hematologic cancers, but their application in solid tumor treatment remains challenging due to the immunosuppressive tumor microenvironment (TME). It is highly significant to develop safe and efficient TME regulatory strategies for the adoptive cellular immunotherapy of tumors. Herein, a TME-responsive nanoimmunomodulator (FMANAC) is designed using a multicomponent coordination self-assembly method to reconstruct the immune chemokine gradient and overcome the suppression of CAR-T cell immunoactivity, thereby improving the infiltration and killing efficiency of CAR-T cells within tumors.

Factors affecting visual outcomes after dural venous sinus stenting in idiopathic intracranial hypertension.

Objectives: This study aimed to identify factors at baseline associated with visual outcomes of patients with idiopathic intracranial hypertension (IIH) with venous sinus stenosis who underwent venous sinus stenting.

Methods: The study eyes were divided into two groups according to mean deviation (MD) at 6-month post-stenting follow-up: MD better than -2.0 dB (the favorable visual outcome group) and equal to -2.

Manganese Ions Chelated Tumosomes as Autologous Cancer Nanovaccines for Effective Suppression of Postsurgical Tumor Relapse.

Autologous cancer vaccines represent a promising strategy to effectively suppress postoperative tumor relapse by eliciting tumor-specific immune responses that highly rely on the efficient internalization and lymph node-targeting delivery of vaccines. Herein, we report an autologous nanovaccine obtained by sequentially incorporating tumor plasma membrane proteins into liposomes, termed tumosomes, and chelating it with metallo-agonist of manganese ions. The yielded Mn-tumosomes with a positively charged surface exhibited significantly enhanced internalization by dendritic cells and enhanced lymph node targeting capacity, the latter of which is indicated by the near-infrared II fluorescence of silver sulfide nanoprobes labeled on their lipid bilayers.

CS-QCFS: Bridging the performance gap in ultra-low latency spiking neural networks.

Spiking Neural Networks (SNNs) are at the forefront of computational neuroscience, emulating the nuanced dynamics of biological systems. In the realm of SNN training methods, the conversion from ANNs to SNNs has generated significant interest due to its potential for creating energy-efficient and biologically plausible models. However, existing conversion methods often require long time-steps to ensure that the converted SNNs achieve performance comparable to the original ANNs.

Regulation of the valleytronic properties in single-layer NbSeCl.

The regulation of the valleytronic properties of two-dimensional materials can contribute to the in-depth study of valley physics and improve its potential for applications in valleytronic devices. Herein, we systematically investigate the electronic properties and the modulation of the valleytronic properties in single-layer NbSeCl. Our results reveal that NbSeCl is a semiconductor with a 105.

The potential mechanisms underlying phthalate-induced hypospadias: a systematic review of rodent model studies.

Objectives: Maternal exposure to environmental endocrine disruptors, such as phthalates, during pregnancy is a significant risk factor for the development of hypospadias. By consolidating existing research on the mechanisms by which phthalates induce hypospadias in rodent models, this systematic review aims to organize and analyze the discovered mechanisms and their potential connections.

Methods: The study involved all articles that explored the mechanisms of phthalate-induced hypospadias using rodent models.

Factors Influencing Favourable Clinical Outcomes in Idiopathic Intracranial Hypertension with Venous Sinus Stenosis Stenting.

Purpose: This study aimed to investigate the factors influencing favourable clinical outcomes in idiopathic intracranial hypertension (IIH) patients with venous sinus stenosis (VSS) who received stenting treatment.

Methods: In this prospective cohort study, we analyzed a total of 172 IIH patients with VSS treated with venous sinus stenting. Clinical outcomes were categorized as either "complete resolved" or "improved".

Rapid, Non-Invasive, Accurate Diagnosis and Efficient Clearance of Metastatic Lymph Nodes.

Sentinel lymph node (SLN) biopsy is currently the standard procedure for clinical cancer diagnosis and treatment, but still faces the risks of false negatives and tumor metastasis, as well as time-consuming pathological evaluation procedure. Herein, we proposed a near-infrared-II (NIR-II, 1000-1700 nm) theranostic nanosystem (FLAGC) for rapid, non-invasive, accurate diagnosis and efficient clearance of metastatic lymph nodes in breast cancer. Initialized by chlorin e6 (Ce6), a pH-sensitive amphiphilic amino acid fluorenylmethoxycarbonyl-L-histidine (Fmoc-His) was assembled with Gd, luminol, and AgAuSe quantum dots (AAS QDs) to form FLAGC.

p-Type AgAuSe Quantum Dots.

Control over the carrier type of semiconductor quantum dots (QDs) is pivotal for their optoelectronic device applications, and it remains a nontrivial and challenging task. Herein, a facile doping strategy via K impurity exchange is proposed to convert the NIR n-type toxic heavy-metal-free AgAuSe (AAS) QDs to p-type. When the dopant reaches saturation at approximately 22.

Shortwave-Infrared Silver Chalcogenide Quantum Dots for Optoelectronic Devices.

Silver chalcogenide (AgX, X = S, Se, Te) semiconductor quantum dots (QDs) have been extensively studied owing to their short-wave infrared (SWIR, 900-2500 nm) excitation and emission along with lower solubility product constant and environmentally benign nature. However, their unsatisfactory photoluminescence quantum yields (PLQYs) make it difficult to obtain optoelectronic devices with high performances. To tackle this challenge, researchers have made great efforts to develop valid strategies to improve the PLQYs of SWIR AgX QDs by suppressing their nonradiative recombination of excitons.

Enhancement-Mode Carbon Nanotube Optoelectronic Synaptic Transistors with Large and Controllable Threshold Voltage Modulation Window for Broadband Flexible Vision Systems.

The development of large-scale integration of optoelectronic neuromorphic devices with ultralow power consumption and broadband responses is essential for high-performance bionics vision systems. In this work, we developed a strategy to construct large-scale (40 × 30) enhancement-mode carbon nanotube optoelectronic synaptic transistors with ultralow power consumption (33.9 aJ per pulse) and broadband responses (from 365 to 620 nm) using low-work function yttrium (Y)-gate electrodes and the mixture of eco-friendly photosensitive AgS quantum dots (QDs) and ionic liquids (ILs)-cross-linking-poly(4-vinylphenol) (PVP) (ILs-c-PVP) as the dielectric layers.

Theoretical Study of the Ternary Compound Monolayer CuPSe for Photocatalytic Water Splitting with Efficient Optical Absorption.

Utilizing photocatalytic method to produce hydrogen by splitting water is an efficient strategy to solve the hotspot issues of energy crisis and environmental pollution. Herein, we systematically investigate the corresponding properties of the reported Cu-bearing ternary compound monolayer CuPSe by using the first-principle calculations. The monolayer CuPSe has quite small cleavage energy of 0.

Ultra-Wideband Ranging Error Mitigation with Novel Channel Impulse Response Feature Parameters and Two-Step Non-Line-of-Sight Identification.

The effective identification and mitigation of non-line-of-sight (NLOS) ranging errors are essential for achieving high-precision positioning and navigation with ultra-wideband (UWB) technology in harsh indoor environments. In this paper, an efficient UWB ranging-error mitigation strategy that uses novel channel impulse response parameters based on the results of a two-step NLOS identification, composed of a decision tree and feedforward neural network, is proposed to realize indoor locations. NLOS ranging errors are classified into three types, and corresponding mitigation strategies and recall mechanisms are developed, which are also extended to partial line-of-sight (LOS) errors.

Programmed Remodeling of the Tumor Milieu to Enhance NK Cell Immunotherapy Combined with Chemotherapy for Pancreatic Cancer.

Natural killer (NK) cell-based adoptive immunotherapy has demonstrated encouraging therapeutic effects in clinical trials for hematological cancers. However, the effectiveness of treatment for solid tumors remains a challenge due to insufficient recruitment and infiltration of NK cells into tumor tissues. Herein, a programmed nanoremodeler (DAS@P/H/pp) is designed to remodel dense physical stromal barriers and for dysregulation of the chemokine of the tumor environment to enhance the recruitment and infiltration of NK cells in tumors.

Extracellular vesicles in plant-microbe interactions: Recent advances and future directions.

Extracellular vesicles (EVs) are membrane-enclosed nanoparticles that have a crucial role in mediating intercellular communication in mammals by facilitating the transport of proteins and small RNAs. However, the study of plant EVs has been limited for a long time due to insufficient isolation and detection methods. Recent research has shown that both plants and plant pathogens can release EVs, which contain various bioactive molecules like proteins, metabolites, lipids, and small RNAs.

High Curie temperature ferromagnetic monolayer T-CrSH and valley physics of T-CrSH/WS heterostructure.

Two-dimensional magnetic materials are attracting widespread attention not only for their excellent applications in spintronic devices but also for their potential to regulate valley splitting, which is crucial for valleytronics. Herein, we design a monolayer Janus ferromagnetic semiconductor T-CrSH by using first-principles calculations. We reveal that monolayer T-CrSH has a magnetic moment of 3 per unit cell, which is primarily contributed by the 3d orbitals of the Cr atom.

New evidence for fractional pressure ratio prediction by pulsatility index from transcranial Doppler in patients with symptomatic cerebrovascular stenosis disease.

Background: The pulsatility index (PI) derived from transcranial Doppler (TCD) assessment may represent the cerebral resistance and altered cerebral blood flow. The purpose of this study was to assess the performance of the TCD PI in correlation with wire-based fractional pressure ratio (FPR).

Methods: This study included 33 patients with symptomatic atherosclerotic lesions of the extracranial and intracranial large arteries, specifically the internal carotid artery, middle cerebral artery (MCA), vertebral artery (VA) V4 segment, and basilar artery (BA), all of which exhibited luminal stenosis ranging from 50% to 70%.