Topological and superconducting properties of two-dimensional MXC [M:X = In:As, Se:As, In:Te and As:Te] by first-principles study.

Topological superconductivity is a fascinating quantum property in the field of condensed matter physics. The exploration of topological superconductivity in two-dimensional (2D) materials has become one of the current hot topics. Based on first-principles calculations, we predict that 2D MXC materials (M:X = In:As, Se:As, In:Te and As:Te) are thermodynamically and dynamically stable.

JAK1/2 Inhibitors Alleviate the Damage of Intercellular Adhesion by Reducing Endoplasmic Reticulum Stress-Induced Apoptosis in Pemphigus Vulgaris.

Pemphigus vulgaris (PV), a severe autoimmune disease with high morbidity and mortality, necessitates innovative therapies to improve outcomes while minimising the adverse effects of conventional immunosuppressants. Immunohistochemical analysis revealed elevated phosphorylated Janus kinase (p-JAK)1 and p-JAK2 expression in PV lesions, complemented by transcriptome data showing JAK/STAT pathway dysregulation. Using a PV acantholysis model, we demonstrated that Ruxolitinib, a JAK1/2 inhibitor, significantly reduced keratinocyte apoptosis, enhanced cell adhesion, and alleviated endoplasmic reticulum (ER) stress.

Theory of Pressure Dependence of Superconductivity in Bilayer Nickelate La_{3}Ni_{2}O_{7}.

A recent experiment showed the superconducting transition temperature in the Ruddlesden-Popper bilayer La_{3}Ni_{2}O_{7} decreases monotonically with increasing pressure above 14 GPa. In order to unravel the underlying mechanism for this unusual dependence, we performed theoretical investigations by combining the density functional theory (DFT) and the unbiased functional renormalization group (FRG). Our DFT calculations show that the Fermi pockets are essentially unchanged with increasing pressure (above 14 GPa), but the bandwidth is enlarged, and particularly the interlayer hopping integral between the nickel 3d_{3z^{2}-r^{2}} orbitals is enhanced.

MHC class II of different non-professional antigen-presenting cells mediate multiple effects of crosstalk with CD4T cells in lung diseases.

The respiratory system is continuously exposed to the outside world, making it vulnerable to airborne particles and harmful pathogens like bacteria and viruses that can enter through breathing. Antigen presenting cells (APCs) have a vital function in the innate immune response as they present antigens to T cells and initiate the response of adaptive immune cells. Professional APCs engulf foreign microorganisms and display their peptides to T lymphocytes using MHC molecules.

Breaking Anionic Solvation Barrier for Safe and Durable Potassium-ion Batteries Under Ultrahigh-Voltage Operation.

Ultrahigh-voltage potassium-ion batteries (PIBs) with cost competitiveness represent a viable route towards high energy battery systems. Nevertheless, rapid capacity decay with poor Coulombic efficiencies remains intractable, mainly attributed to interfacial instability from aggressive potassium metal anodes and cathodes. Additionally, high reactivity of K metal and flammable electrolytes pose severe safety hazards.

P2-NaMnNiCoO stabilized by optimal active facets for sodium-ion batteries.

Considering factors such as crustal reserves, atomic mass, redox potential and energy density, sodium-ion batteries (SIBs) are regarded as the most promising alternative to lithium-ion batteries (LIBs). Transition metal-based layered oxides, especially typical NaMnO, stand out among cathode materials due to their low cost and high energy density. However, NaMnO cathodes face several challenges, including Jahn-Teller distortion, manganese dissolution, structural collapse, irreversible phase transition and significant capacity loss.

Visualization of the relationship between metabolism and lung diseases from the perspective of bibliometric analysis: research trends and future prospects.

Background: Extensive research has examined the role of metabolism in lung disease development, yet a comprehensive literature review remains absent despite numerous publications.

Objective: This study aims to visualize and assess the advancements in research on metabolism and its role in lung diseases.

Methods: Publications from January 1, 1991, to April 30, 2024, related to lung diseases and metabolism were sourced from the Web of Science Core Collection and analyzed using CiteSpace 6.

Over-activation of iNKT cells aggravate lung injury in bronchopulmonary dysplasia mice.

Bronchopulmonary dysplasia (BPD) is a severe lung disease in preterm infants, the abnormal proliferate and differentiate ability of type II epithelial cells (AEC II) is the key to the pathological basis of BPD. Mechanisms regarding abnormal AEC II in BPD remain unclear. The present work investigated the role and mechanisms of invariant natural killer T (iNKT) cells in lung disorder in BPD using public datasets, clinical samples, a hyperoxia-induced BPD mouse model and AEC II-iNKT cells transwell co-culture system.

Direct and rapid thermal shock for recycling spent graphite in lithium-ion batteries.

Due to the rapid increase in the number of spent lithium-ion batteries, there has been a growing interest in the recovery of degraded graphite. In this work, a rapid thermal shock (RTS) strategy is proposed to regenerate spent graphite for use in lithium-ion batteries. The results of structural and morphological characterization demonstrate that the graphite is well regenerated by the RTS process.

Role of regulatory T cells in mouse lung development.

Regulatory T cells (Tregs) constitute a specialized subset of T cells with dual immunoregulatory and modulatory functions. Recent studies have reported that Tregs mediate immune responses and regulate the development and repair processes in non-lymphoid tissues, including bone and cardiac muscle. Additionally, Tregs facilitate the repair and regeneration of damaged lung tissues.

Superconductivity in Ca-intercalated bilayer graphene: CCaC.

The deposition and intercalation of metal atoms can induce superconductivity in monolayer and bilayer graphenes. For example, it has been experimentally proved that Li-deposited graphene is a superconductor with critical temperature of 5.9 K, Ca-intercalated bilayer graphene CCaC and K-intercalated epitaxial bilayer graphene CKC are superconductors with of 2-4 K and 3.

ILC2 influence the differentiation of alveolar type II epithelial cells in bronchopulmonary dysplasia mice.

Bronchopulmonary dysplasia, a common complication of premature infants, is mainly characterized by blocked alveolarization. Proverbially, the injury of alveolar type II epithelial cells is regarded as the pathologic basis of occurrence and development of bronchopulmonary dysplasia. In the case of alveolar epithelial damage, alveolar type II epithelial cells can also differentiate to alveolar type I epithelial cells as progenitor cells.

Hydrogenation induced high-temperature superconductivity in two-dimensional WC.

The discovery of highly crystalline two-dimensional (2D) superconductors provides a new alluring branch for exploring the fundamental significances. Based on first-principles calculations, we predict a new kind of 2D stable material WC, which is a semimetal but not a superconductor because of the weak electron-phonon coupling (EPC) strength. After hydrogenation, WCH possesses the intrinsic metallic properties with a large density of states (DOS) at the Fermi energy ().

Type 2 innate lymphoid cell-derived amphiregulin regulates type II alveolar epithelial cell transdifferentiation in a mouse model of bronchopulmonary dysplasia.

Bronchopulmonary dysplasia (BPD) is a common complication in preterm infants characterized by alveolar growth arrest. Interleukin (IL)-33 and type 2 innate lymphoid cell (ILC2) affect type II alveolar epithelial cell (AECII) differentiation in BPD mice and may cause increased lung epithelial-mesenchymal transition (EMT). Amphiregulin (AREG) can be produced by ILC2 and is associated with tissue repair.

Pearl-Structure-Enhanced NASICON Cathode toward Ultrastable Sodium-Ion Batteries.

Based on the favorable ionic conductivity and structural stability, sodium superionic conductor (NASICON) materials especially utilizing multivalent redox reaction of vanadium are one of the most promising cathodes in sodium-ion batteries (SIBs). To further boost their application in large-scale energy storage production, a rational strategy is to tailor vanadium with earth-abundant and cheap elements (such as Fe, Mn), reducing the cost and toxicity of vanadium-based NASICON materials. Here, the Na V Fe (PO ) (NVFP) is synthesized with highly conductive Ketjen Black (KB) by ball-milling assisted sol-gel method.

Nanodesigns for NaV(PO)-based cathode in sodium-ion batteries: a topical review.

With the rapid development of sodium-ion batteries (SIBs), it is urgent to exploit the cathode materials with good rate capability, attractive high energy density and considerable long cycle performance. NaV(PO)(NVP), as a NASICON-type electrode material, is one of the cathode materials with great potential for application because of its good thermal stability and stable. However, NVP has the inherent problem of low electronic conductivity, and various strategies are proposed to improve it, moreover, nanotechnology or nanostructure are involved in these strategies, the construction of nanostructured active particles and nanocomposites with conductive carbon networks have been shown to be effective in improving the electrical conductivity of NVP.

Superconductivity of monolayer functionalized biphenylene with Dirac cones.

Monolayer biphenylene is a new two-dimensional (2D) carbon allotrope, which has been experimentally synthesized and theoretically predicted to show superconductivity. In this work, we investigate functionalized biphenylene with the adsorption of Li. The superconducting critical temperature () can be pushed from 0.

IL-33-ST2 pathway regulates AECII transdifferentiation by targeting alveolar macrophage in a bronchopulmonary dysplasia mouse model.

Evidence points to the indispensable function of alveolar macrophages (AMs) in normal lung development and tissue homeostasis. However, the importance of AMs in bronchopulmonary dysplasia (BPD) has not been elucidated. Here, we identified a significant role of abnormal AM proliferation and polarization in alveolar dysplasia during BPD, which is closely related to the activation of the IL-33-ST2 pathway.

Successful surgical treatment of polybacterial gas gangrene confirmed by metagenomic next-generation sequencing detection: A case report.

Background: We report on a case of detected by metagenomics next-generation sequencing (mNGS) in a 53-year-old male patient with polymicrobial gas gangrene and successful treatment by surgery. This report raises awareness among dermatologists that when a patient is clinically suspected of a special type of pathogenic infection, the mNGS method should be preferred to identify the patient's pathogen infection as soon as possible and then take effective treatment in time to save patients' lives.

Case Summary: A 53-year-old male who worked in the aquatic market complained of redness and swelling of the lower limbs, blisters and ulcers with fever for 3 d.