this pilot study aimed to evaluate the diagnostic accuracy of ChatGPT-4o in analyzing oral mucosal lesions from clinical images. : a total of 110 clinical images, including 100 pathological lesions and 10 healthy mucosal images, were retrieved from Google Images and analyzed by ChatGPT-4o using a standardized prompt. An expert panel of five clinicians established a reference diagnosis, categorizing lesions as benign or malignant.
View Article and Find Full Text PDFEctrodactyly-ectodermal dysplasia-cleft (EEC) syndrome is a rare genetic disorder presenting significant challenges for dental rehabilitation due to severe maxillary atrophy and altered anatomy. This report describes a 23-year-old female with EEC syndrome successfully rehabilitated using a custom-made subperiosteal implant. Despite multiple grafting procedures, conventional implants were not viable.
View Article and Find Full Text PDFTAS2R38 is the T2R receptor primarily associated with the innate immune response of the respiratory system. It activates a response mediated by nitric oxide (NO), which has been shown to inhibit the replication of SARS-CoV-2. TAS2R38 polymorphisms (SNPs) that decrease receptor functionality contributing to individual differences in susceptibility to airway infections.
View Article and Find Full Text PDFBackground: Total maxillectomy for malignant tumors presents significant challenges for functional and aesthetic rehabilitation. Advances in digital planning and additive manufacturing have reintroduced subperiosteal implants as a promising solution for primary reconstructions.
Case Report: This report details the case of a 59-year-old male with squamous cell carcinoma of the hard palate extending contralaterally, treated with a total maxillectomy and primary reconstruction using an osteomyocutaneous fibula free flap combined with a custom-made, additively manufactured subperiosteal implant.
Clin Neurophysiol
May 2025
Objective: To explore the excitability and sensory motor integration of the face and masticatory primary motor cortex (M1), and recognition of face expressions in individuals with dentofacial deformities (IDD).
Methods: Short-interval intracortical inhibition (SICI), short-afferent inhibition (SAI) of masticatory and face M1, the blink reflex and face expressions recognition (FER) ability were assessed in 18 healthy subjects (HS) (24.56 ± 1.
Severe atrophy in isolated posterior maxillary sectors poses challenges for dental rehabilitation, especially in partially dentate patients where traditional graftless techniques are unsuitable. This study retrospectively analyzed the outcomes of sectional rehabilitation in 16 consecutive patients with Cawood and Howell class V to VI atrophy treated with 21 custom fabricated subperiosteal implants. Patients were followed for a median of 36 months (interquartile range: 24 to 48).
View Article and Find Full Text PDFCondylectomy is a delicate and intricate procedure commonly employed in the management of temporomandibular joint (TMJ) disorders, osteochondromas, condylar hyperplasia, hemimandibular hyperplasia, and other pathologies affecting the condylar region. The advent of surgical cutting guides has introduced a new dimension to condylectomy procedures as they enable surgeons to plan and execute precise cuts with a heightened level of accuracy. In the literature already exists cases of cutting guide-based condylectomy, but they only depend on the mere mirroring procedure in virtual planning, which has accuracy limitations because it does not consider asymmetry of peri-condylar structures at the level of the ramus, body, and mandibular angle.
View Article and Find Full Text PDFObjective: This study aims to evaluate the impact of prompt construction on the quality of artificial intelligence (AI) chatbot responses in the context of head and neck surgery.
Study Design: Observational and evaluative study.
Setting: An international collaboration involving 16 researchers from 11 European centers specializing in head and neck surgery.
This study evaluates the quality and readability of informed consent documents generated by AI platforms ChatGPT-4 and Bard Gemini Advanced compared to those written by a first-year oral surgery resident for common oral surgery procedures. The evaluation, conducted by 18 experienced oral and maxillofacial surgeons, assessed consents for accuracy, completeness, readability, and overall quality. ChatGPT-4 consistently outperformed both Bard and human-written consents.
View Article and Find Full Text PDFJ Stomatol Oral Maxillofac Surg
September 2024
Eur Arch Otorhinolaryngol
November 2024
Indian J Otolaryngol Head Neck Surg
February 2024
Acta Otorhinolaryngol Ital
February 2024
Objective: To translate and validate an Italian version of the Questionnaire of Olfactory Disorders (IT-QOD).
Materials And Methods: This is a prospective, multicentre study that involved patients with olfactory dysfunction (OD). Both cases and controls underwent administration of the IT-QOD, Sino-Nasal Outcome Test-22 (SNOT-22) and psychophysical evaluation of orthonasal and retronasal olfactory function.
Facial palsy can severely compromise quality of life, significantly altering the harmony and symmetry of the face, which can be restored by surgical rehabilitation. The aim of the study was the quantification of facial symmetry following facial reanimation. Fifteen consecutive adult patients were surgically treated through triple innervation for reanimation of flaccid unilateral facial paralysis (contralateral facial nerve, masseteric nerve, and hypoglossal nerve) and fascia lata graft for definition of the nasolabial sulcus.
View Article and Find Full Text PDFObjective: To investigate the accuracy of Chat-Based Generative Pre-trained Transformer (ChatGPT) in answering questions and solving clinical scenarios of head and neck surgery.
Study Design: Observational and valuative study.
Setting: Eighteen surgeons from 14 Italian head and neck surgery units.