Gastric Submucosal Tumor in Patient Infected with Dioctophyme renale Roundworm, South Korea, 2024.

We describe a case of a gastric submucosal tumor in a patient in South Korea infected with Dioctophyme renale roundworm. The patient had a history of consuming raw freshwater fish. Molecular and morphologic analyses confirmed D.

Effect of tool center point angles on drilling performance in robotic cortical bone procedures.

This study investigates the effects of different tool center point (TCP) angles on drilling precision and accuracy in cortical bone using a six-axis robot. Tool paths were generated using simulation software, and various TCP angles and corresponding robot postures were implemented in a real-world setting. To assess dynamic characteristics, experimental modal analysis was performed to measure natural frequencies and damping ratios (DRs) across the different configurations.

A Case of Intestinal Schistosomiasis with Concurrent Hepatic and Gastrointestinal Involvement Diagnosed by Computed Tomography.

Intestinal schistosomiasis is an uncommon disease that can present with a range of clinical symptoms and colonoscopic findings, depending on the affected organ, disease extent, and duration. Because these manifestations are not disease-specific, diagnosis can be difficult without clinical suspicion. In addition to fecal examinations to detect parasite eggs, computed tomography (CT) plays a crucial role in diagnosing intestinal schistosomiasis because it can reveal hallmark calcification patterns that are strongly suggestive of Schistosoma infection.

Low-Latency Edge-Enabled Digital Twin System for Multi-Robot Collision Avoidance and Remote Control.

This paper proposes a low-latency and scalable architecture for Edge-Enabled Digital Twin networked control systems (E-DTNCS) aimed at multi-robot collision avoidance and remote control in dynamic and latency-sensitive environments. Traditional approaches, which rely on centralized cloud processing or direct sensor-to-controller communication, are inherently limited by excessive network latency, bandwidth bottlenecks, and a lack of predictive decision-making, thus constraining their effectiveness in real-time multi-agent systems. To overcome these limitations, we propose a novel framework that seamlessly integrates edge computing with digital twin (DT) technology.

Severe Fever with Thrombocytopenia Syndrome Acquired through Dog Bite, South Korea.

A veterinary technician in South Korea contracted severe fever with thrombocytopenia syndrome virus from a dog bite. Molecular evidence, including PCR sequencing, supports dog-to-human transmission. The case underscores the zoonotic risks posed by companion animals and highlights the importance of preventive measures.

Serum melatonin as a potential biomarker for COVID-19 severity.

With the ongoing global burden of COVID-19, identifying reliable biomarkers to predict disease severity remains a clinical priority. Melatonin, a hormone with immunomodulatory and antioxidant properties, has garnered attention for its potential role in regulating inflammation during viral infections. However, the relationship between serum melatonin levels and COVID-19 severity remains poorly understood.

Molecular detection of Anaplasma phagocytophilum and Rickettsia monacensis in trombiculid mite pools collected from wild rodents in Korea: Implications for potential mite-borne transmission.

Mite-borne diseases have been extensively studied; however, limited research has focused on the detection of Rickettsia species other than Orientia tsutsugamushi in Korean mites. Polymerase chain reaction (PCR) assays were performed using mites collected from rodents. Nested PCR (N-PCR) targeting the 56 kDa gene of O.

Revolutionizing Lyme disease vaccination: a systematic review and meta-analysis of promising candidates.

The most prevalent vector-borne diseases in North America and Europe is still Lyme disease, which is caused by the bacterium . As incidence rates rise, this poses a serious threat to public health. Since there is presently no vaccine for Lyme disease that is suitable for human use after the LYMErix vaccine was withdrawn in 2002 due to safety issues and insufficient adoption, there is an urgent need for an effective vaccination to protect at-risk populations.

Design of a High-Gain Multi-Input LNA with 16.4 Degree Phase Shift Within the 32 dB Gain Range.

This paper presents a high-gain multi-input low-noise amplifier (LNA) design aimed at achieving stable phase and minimal noise within a flexible gain range for modern wireless communication systems. The proposed LNA, designed using a CASCODE architecture and implemented in a 65 nm silicon-on-insulator (SOI) process, demonstrates significant improvements in isolation, noise reduction, and miniaturization. The SOI process reduces parasitic capacitance, enhancing performance and thermal/electrical isolation, critical for high-frequency applications.

A case of an asymptomatic Plasmodium falciparum infection followed by a symptomatic Plasmodium ovale infection in a soldier deployed to South Sudan.

Background: Asymptomatic malaria poses a significant challenge to malaria eradication efforts and delays global elimination strategies. Mixed infections are also a major concern, as they frequently relapse, increase the risk of severe malaria, require more accurate diagnosis for appropriate treatment, and contribute to the development of drug resistance.

Case Presentation: A 25-year-old soldier was diagnosed with malaria following deployment in South Sudan.

PCR sequencing and re-evaluation of pathologic findings revealed invasive fungal sinusitis caused by Malassezia restricta.

Objective: To describe a rare case of invasive fungal sinusitis caused by Malassezia restricta in a patient with diabetes and emphasize the diagnostic difficulties and significance of molecular techniques.

Study Design: An 85-year-old man with diabetes presented with unresolved left sphenoiditis despite a sphenoidotomy and antibiotics. Imaging findings indicated invasive fungal sinusitis.

Secondary syphilis with oropharyngeal and skin lesions confirmed by PCR mimicking chicken pox or mpox in a patient with HIV.

Syphilis, caused by Treponema pallidum, can mimic infections like chickenpox and mpox, especially in patients with HIV, making diagnosis challenging. This case involved a 30-year-old HIV-positive man who presented with fever, sore throat, and widespread rash. He was initially suspected to have a viral illness and was therefore treated with acyclovir.

Increased survival rate of selected probiotics under environmental stresses through encapsulation in α-glucan-coated porous starch granules.

Porous starch granules (PSGs) produced by amylolytic enzymes show potential as an effective delivery system for various materials, including probiotics. This study developed α-glucan-coated PSGs (α-gcPSGs) to enhance probiotic viability under environmental stresses. Lactobacillus rhamnosus GG and Bifidobacterium longum were encapsulated in α-gcPSGs coated with amylosucrase-produced α-glucan.

Analysis of Changes in Viral Load and Inflammatory Cytokines, as Well as the Occurrence of Secondary Infections, in SFTS Patients Treated with Specific Treatments: A Prospective Multicenter Cohort Study.

Severe fever with thrombocytopenia syndrome (SFTS) is an acute febrile illness caused by the SFTS virus (SFTSV). We conducted this study to propose a scientific evidence-based treatment that can improve prognosis through changes in viral load and inflammatory cytokines according to the specific treatment of SFTS patients. This prospective and observational study was conducted at 14 tertiary referral hospitals, which are located in SFTS endemic areas in Korea, from 1 May 2018 to 31 October 2020.

A 0.73 dB Multi-Gain Low Noise Amplifier Design with Fast Mode-Switching for 5G/4G Applications.

In this paper, a sub-1dB Low Noise Amplifier (LNA) with several gain modes, including amplification and attenuation modes required for the fifth and fourth generations (5G/4G) of mobile network applications, is proposed. Its current consumption is adaptive for every gain mode and varies to lower currents for lower amplifications due to the importance of current consumption for mobile network applications. The proposed LNA features an innovative architecture with a three-core input structure supporting multi-gain modes, achieving high gain and ultra-low noise performance.

Innovative Hybrid Nanocomposites in 3D Printing for Functional Applications: A Review.

3D printing has garnered significant attention across academia and industry due to its capability to design and fabricate complex architectures. Applications such as those requiring intricate geometries or custom designs, including footwear, healthcare, energy storage, and electronics applications, greatly benefit from exploiting 3D printing processes. Despite the recent advancement of structural 3D printing, its use in functional devices remains limited, requiring the need for the development of functional materials suitable for 3D printing in device fabrication.

Analysis of Clinical and Laboratory Profiles of Patients Hospitalized with Hemorrhagic Fever with Renal Syndrome in Southwestern South Korea.

Hemorrhagic fever with renal syndrome (HFRS) is caused by hantaviruses. Data of 34 patients with HFRS hospitalized at Chosun University Hospital, South Korea, between 2010 and 2021 were retrospectively analyzed. Nested reverse transcription polymerase chain reaction (RT-nPCR) targeting the L segment of hantavirus and sequencing were used for diagnosis.

Risk factors of thromboembolic events in patients with scrub typhus.

Background: Thromboembolic events are a well-recognized cause of in-hospital deaths of patients with infectious diseases. However, thromboembolic events in patients with scrub typhus, caused by Orientia tsutsugamushi have rarely been reported. This study aimed to assess risk factors associated with thromboembolic events in patients with scrub typhus.

Characterization and Making Techniques of Calcareous Construction Materials for Phaya Thon Zu Temple in Bagan Historical Area, Myanmar.

The calcareous materials used in constructing the Phaya Thon Zu temple at the Bagan historical sites in Myanmar are mortars, plasters, and stuccos. Among them, the mortars and plasters are a mixture of original and new materials used for recent conservation treatments. In this study, the making techniques were examined through analysis of calcareous materials by production period.

Comparable Efficacy of Lopinavir/Ritonavir and Remdesivir in Reducing Viral Load and Shedding Duration in Patients with COVID-19.

The spread of COVID-19 has significantly increased research on antiviral drugs and measures such as case isolation and contact tracing. This study compared the effects of lopinavir/ritonavir and remdesivir on COVID-19 patients with a control group receiving no antiviral drugs. Patients confirmed to have a SARS-CoV-2 infection via real-time RT-PCR were divided into three groups: lopinavir/ritonavir, remdesivir, and control.

Risk Factors for Impaired Cellular or Humoral Immunity after Three Doses of SARS-CoV-2 Vaccine in Healthy and Immunocompromised Individuals.

We aimed to identify the risk factors for impaired cellular and humoral immunity after three doses of the SARS-CoV-2 vaccine. Six months after the third vaccine dose, T-cell immunity was evaluated using interferon-gamma release assays (IGRAs) in 60 healthy and 139 immunocompromised (IC) individuals, including patients with hematologic malignancy (HM), solid malignancy (SM), rheumatic disease (RD), and kidney transplantation (KT). Neutralizing antibody titers were measured using the plaque reduction neutralization test (PRNT) and surrogate virus neutralization test (sVNT).

Experimental Analysis of Robotic Cortical Bone Specimen Drilling Performance: Effect of Cryogen.

In orthopedic surgery, precise bone screw insertion is crucial for stabilizing fractures, necessitating a preliminary cortical bone drilling procedure. However, this process can induce temperatures exceeding 70 °C due to the low thermal conductivity of cortical bone, potentially leading to thermal osteonecrosis. Furthermore, significant cutting forces and torque pose risks of tool breakage and bone damage, underlining the need for high precision and optimal processing parameters.

Quantifying the regime of thermodynamic control for solid-state reactions during ternary metal oxide synthesis.

The success of solid-state synthesis often hinges on the first intermediate phase that forms, which determines the remaining driving force to produce the desired target material. Recent work suggests that when reaction energies are large, thermodynamics primarily dictates the initial product formed, regardless of reactant stoichiometry. Here, we validate this principle and quantify its constraints by performing in situ characterization on 37 pairs of reactants.

SARS-CoV-2 antigenemia and RNAemia in association with disease severity in patients with COVID-19.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for COVID-19, causes a spectrum of symptoms ranging from mild upper to severe lower respiratory tract infections. However, the dynamics of nucleocapsid (N) protein antigenemia and RNAemia are not fully understood. We conducted a cohort study involving 117 patients with clinically confirmed COVID-19, focusing on the kinetics of antigenemia and RNAemia and their association with various clinical characteristics.