Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Asymptomatic malaria poses a significant challenge to malaria eradication efforts and delays global elimination strategies. Mixed infections are also a major concern, as they frequently relapse, increase the risk of severe malaria, require more accurate diagnosis for appropriate treatment, and contribute to the development of drug resistance.
Case Presentation: A 25-year-old soldier was diagnosed with malaria following deployment in South Sudan. A comprehensive survey identified an asymptomatic Plasmodium falciparum infection, confirmed by peripheral blood smear and polymerase chain reaction (PCR). Despite being discharged after treatment, the patient developed fever and other symptoms one month later. Subsequent laboratory tests confirmed Plasmodium ovale infection based on peripheral blood smears and PCR.
Conclusion: This case underscores the importance of molecular detection for surveillance and vigilant follow-up in malaria management, particularly among patients with a history of deployment in endemic regions. The detection of P. ovale after treatment for P. falciparum highlights the need for increased awareness and testing for mixed infections to ensure effective malaria control strategies.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11983915 | PMC |
| http://dx.doi.org/10.1186/s12936-025-05329-2 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Prevalence of Malaria Among Pregnant Women at a Tertiary Care Hospital in Somalia: A Cross-Sectional Study.
Biomed Res Int
September 2025
Department of Biostatistics and Medical Informatics, Faculty of Medicine, Kahramanmaraş Sütçü Imam University, Kahramanmaraş, Türkiye.
In countries like Somalia, where health infrastructure is inadequate and malaria is endemic, immunosuppression during pregnancy increases the risk of placental malaria; this, in turn, leads to anemia, low birth weight, preterm delivery, and stillbirth, causing severe complications that pose a life-threatening risk to both the mother and fetus. The aim of this study was to investigate the prevalence and associated factors of malaria parasitemia among pregnant women attending the obstetric clinic of a tertiary hospital in Somalia. This cross-sectional study, conducted from November 2022 to January 2023 at a tertiary hospital in Mogadishu, involved 398 pregnant women.
View Article and Find Full Text PDFOptimizing MDA and antimalarial treatment in the presence of drug resistance for effective malaria control.
Math Biosci Eng
June 2025
MIVEGEC, Univ. Montpellier, CNRS, IRD, Montpellier, France.
Antimalarial drugs are critical for controlling malaria, but the emergence of drug resistance poses a significant challenge to global eradication efforts. This study explores strategies to minimize resistance prevalence and improve malaria control, particularly through the use of mass drug administration (MDA) in combination with antimalarial drugs. We develop a compartmental mathematical model that incorporates asymptomatic, paucisymptomatic, and clinical states of infection and evaluates the impact of resistance mutations on transmission dynamics.
View Article and Find Full Text PDFLongitudinal analysis of the prevalence of minor spp. in the reservoir of asymptomatic infections through sequential interventions in Northern Sahelian Ghana.
medRxiv
August 2025
Department of Microbiology and Immunology, Bio21 Institute and Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC, Australia.
Current interventions targeting malaria control in sub-Saharan Africa (SSA) are focused on , the most prevalent species infecting humans. Despite renewed efforts for malaria elimination in SSA, little attention has been paid to the neglected parasites and spp. and the impact of interventions like long-lasting insecticidal nets (LLINs), indoor residual spraying (IRS) with non-pyrethroid insecticides, and/or seasonal malaria chemoprevention (SMC) on these minor spp.
View Article and Find Full Text PDFPatterns of patent and sub-patent Plasmodium falciparum infections in household members of children under seasonal malaria chemoprevention coverage in the health district of Nanoro, Burkina Faso.
Malar J
September 2025
Institut de Recherche en Sciences de La Santé (IRSS), ClinicalResearch Unit of Nanoro (CRUN), Nanoro, Burkina Faso.
Background: Seasonal Malaria Chemoprevention (SMC) has been adopted since 2014 in Burkina Faso to reduce malaria burden in children under 5 years. However, the intervention's expected potential has not yet been achieved in real-life conditions, suggesting other factors may influence its effectiveness. Asymptomatic carriers, including patent and sub-patent Plasmodium falciparum infections in household members seems to be a potential factor maintaining the high malaria burden in children under SMC coverage.
View Article and Find Full Text PDFMalaria care-seeking behaviours and infection prevalence among short-term Myanmar migrants in Thailand.
Malar J
September 2025
Department of Population Health and Disease Prevention, Department of Epidemiology & Biostatistics, University of California, Irvine, CA, USA.
Background: The recent resurgence of malaria in western Thailand has coincided with increased cross-border migration from Myanmar following political unrest. As short-term migrants from endemic areas may contribute to sustained local transmission, this study examined their malaria care-seeking behaviours and infection prevalence.
Methods: A community-based cross-sectional study was conducted during March-April 2025 in six malaria-endemic villages of Tha Song Yang District, Tak Province, western Thailand.