Optimizing MDA and antimalarial treatment in the presence of drug resistance for effective malaria control.

Antimalarial drugs are critical for controlling malaria, but the emergence of drug resistance poses a significant challenge to global eradication efforts. This study explores strategies to minimize resistance prevalence and improve malaria control, particularly through the use of mass drug administration (MDA) in combination with antimalarial drugs. We develop a compartmental mathematical model that incorporates asymptomatic, paucisymptomatic, and clinical states of infection and evaluates the impact of resistance mutations on transmission dynamics.

Global dynamics of a vaccination model for infectious diseases with asymptomatic carriers.

In this paper, an epidemic model is investigated for infectious diseases that can be transmitted through both the infectious individuals and the asymptomatic carriers (i.e., infected individuals who are contagious but do not show any disease symptoms).

Effect of genotype of cocoa (Theobroma cacao) on attractiveness to the mirid Sahlbergella singularis (Hemiptera: Miridae) in the laboratory.

Background: Mirids are a major constraint to cocoa growing in Africa. Cocoa breeding for tolerance/resistance could be effective in an integrated pest management system. Attractiveness is one aspect of tolerance/resistance, and decreasing the attractiveness of cocoa trees should be a good way of reducing damage.

Global stability analysis for SEIS models with n latent classes.

We compute the basic reproduction ratio of a SEIS model with n classes of latent individuals and bilinear incidence. The system exhibits the traditional behaviour. We prove that if R(0) < or = 1, then the disease-free equilibrium is globally asymptotically stable on the nonnegative orthant and if R (0) > 1, an endemic equilibrium exists and is globally asymptotically stable on the positive orthant.

Stability analysis of within-host parasite models with delays.

We provide a global analysis of systems of within-host parasitic infections. The systems studied have parallel classes of different length of latently infected target cells. These systems can also be thought as systems arising from within-host parasitic systems with distributed continuous delays.