Research trends of music in children with autism: a bibliometric analysis.

Introduction: The impact of music on children with autism-a condition marked by deficits in social interaction, communication, and behavior-has become a significant area of research. This study investigates current trends, key contributors, and emerging interests regarding music's effects on this population.

Methods: A comprehensive review of publications from 1953 to 2024 on the influence of music on children with autism was conducted using the Web of Science Core Collection.

: explore its carcinogenic potential and understand its role, prognostic value and biological significance in pan-cancer.

Background: The protein belongs to the family and is primarily localized to early endosomes. It regulates the endocytic pathway through its GTPase activity, thereby affecting various aspects such as cell signaling and metabolic regulation. Dysfunction of is closely associated with the progression and deterioration of multiple types of tumors.

Inflammation Inhibits HECTD1-Mediated AURKA Ubiquitination to Cause Extracellular Matrix Degradation in Osteoarthritis via Enhancing Cap-Dependent mRNA Translation of ADAMTS12.

Osteoarthritis (OA) is a common joint disease, and chondrocyte extracellular matrix (ECM) degradation was closely associated with its progression. This study investigated the regulatory mechanisms of ECM degradation during OA development. A rat model of OA was established by anterior cruciate ligament transection (ACL-T) and interleukin-1 beta (IL-1β)-stimulated rat chondrocytes were used to simulate OA in vitro.

Construction of a predictive model for concurrent infection in liver failure patients based on prognostic nutritional index and inflammatory cytokine analysis.

Objective: This study aimed to explore the relationship between the Prognostic Nutritional Index (PNI, a composite indicator of albumin and lymphocyte count reflecting nutritional and immune status) and inflammatory cytokines in predicting infections among liver failure patients, and to construct a predictive model based on these indicators.

Methods: A retrospective analysis was conducted on 163 patients with liver failure admitted to our hospital between January 2020 and December 2023. Patients were categorized into an Infection group and a Non-infection group based on the presence of concurrent infections.

Correction: : insights into its oncogenic potential, prognostic value, and impact on immune microenvironment across cancers.

[This corrects the article DOI: 10.3389/fimmu.2025.

EGR3 Transcriptionally Upregulates the Expression of DCN in Liver Cancer to Inhibit Tumor Progression.

Decorin (DCN), a multifunctional extracellular matrix protein, has been reported to exhibit tumor-suppressive effects in various cancers, including liver cancer. However, the transcriptional regulatory mechanisms of DCN in liver cancer remains unclear. We analyzed DCN expression in liver cancer cells using qPCR and Western blot.

: insights into its oncogenic potential, prognostic value, and impact on immune microenvironment across cancers.

Background: () is a zinc finger transcription factor gene that regulates gene expression by recognizing and binding to specific DNA sequences. Preliminary studies have suggested that plays a pivotal role in the invasion and metastasis of various solid cancers. However, its role within the tumor immune microenvironment, as well as its prognostic value and potential for predicting responses to immunotherapy across different cancer types, remains inadequately explored and warrants a comprehensive systematic analysis.

Intestinal inflammation mediates PFOA-induced sleep fragmentation and growth impairment in Drosophila.

Perfluorooctanoic acid (PFOA), a persistent synthetic perfluorinated compound with widespread environmental distribution, bioaccumulates in organisms, raising concerns about potential adverse health effects. While previous studies suggest a correlation between PFOA exposure levels and altered sleep architecture, the specific consequences of chronic PFOA exposure on sleep regulation and the underlying mechanisms remain poorly understood. Utilizing Drosophila melanogaster as a model system, we investigated the effects of PFOA exposure.

Genome-Wide Identification, Characterization, and Expression Analysis of Gene Family in Under Abiotic Stresses and Hormone Treatments.

The valine glutamine (VQ) proteins are transcription cofactors involved in various aspects of plant biology, including growth, development, and stress resistance, making them an attractive target for genetic engineering aimed at enhancing plant resilience and productivity. However, comprehensive reports or systematic studies on VQ cofactors in remain lacking. In this study, we analyzed genes using bioinformatics methods based on the genome database.

Comprehensive Identification of Family Genes in L. and Their Potential Roles in Response to Abiotic Stress.

(homeodomain-leucine zipper) transcription factors play a crucial role in plant growth, development, and stress response; however, the gene family of L. has not been identified. In this study, a total of 40 gene family members were identified in the genome of Coix.

Elemental Imbalances After Manganese Exposure and the Regulatory Potential of Curcumin.

Long-term exposure to excess manganese can lead to a condition known as manganism, which is characterized by irreversible neuropsychiatric and extrapyramidal dysfunction resembling Parkinson's disease. Excessive exposure to manganese not only increases manganese levels in the body, but can also disrupt the homeostasis of other trace elements. Elemental imbalance has been reported as a risk factor for several neurodegenerative diseases, and restoring elemental homeostasis may be a potential strategy to combat these conditions.

miR-125b-5p regulates FFA-induced hepatic steatosis in L02 cells by targeting estrogen-related receptor alpha.

Background & Aims: NAFLD is a global and complex liver disease caused by multiple factors. Intrahepatocellular steatosis is the primary prerequisite for the occurrence and development of NAFLD. It has been shown that miR-125b-5p is highly correlated with NAFLD, and ESRRA is a factor that regulates lipid metabolism.

Predictive Value of Serum Lactate Levels for Mortality in Patients with Hepatitis B-Related Decompensated Cirrhosis: A Retrospective Analysis.

Decompensated cirrhosis is characterized by the progression of cirrhosis from an asymptomatic state to elevated portal pressure and marked deterioration of liver function. This pathological condition progresses rapidly following onset, significantly raising the risk for mortality. The aim of this study is to explore the association between serum lactate concentrations and mortality rates in individuals with hepatitis B-induced decompensated cirrhosis and to evaluate its potential as a clinical prognostic indicator.

Establishment and evaluation of a carotid artery dissection model in rats.

Background: Given the lack of models for carotid artery dissections (CAD), we aim to investigate effects of beta-aminopropionitrile (BAPN) combined with physical damage on the arterial walls of rats, and to establish a high-incidence and low-mortality CAD model.

Methods: Sixteen SPF SD rats (3-week-old) were divided into two groups. Group B was given 0.

Influence of acupuncture and moxibustion on gastrointestinal function and adverse events in gastric cancer patients after surgery and chemotherapy: a meta-analysis.

Objective: The impact of acupuncture and moxibustion on postoperative complications and adverse events (AEs) of chemotherapy in patients with gastric cancer (GC) has been investigated. Through a meta-analysis of existing randomized controlled trials (RCTs), this study sought to strengthen the evidentiary basis to help investigators further understand the effects of moxibustion and acupuncture on postoperative complications and AEs of chemotherapy among GC patients.

Methods: Embase, Web of Science, PubMed, The Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang Database, and VIP Database for Chinese Technical Periodicals were searched to collect RCTs on effects of acupuncture and moxibustion on gastrointestinal function and AEs among GC patients undergoing surgery and chemotherapy.

Protocol to construct humanized mice with adult CD34 hematopoietic stem and progenitor cells.

Humanized mice, defined as mice with human immune systems, have become an emerging model to study human hematopoiesis, infectious disease, and cancer. Here, we describe the techniques to generate humanized NSGF6 mice using adult human CD34 hematopoietic stem and progenitor cells (HSPCs). We describe steps for constructing and monitoring the engraftment of humanized mice.

Cross-sectional study on the epidemiological investigation ability of professional staff from Centers for Disease Control and Prevention in Guizhou Province.

Introduction: This study aims to evaluate the qualifications and identify skill enhancement areas for epidemiological investigators in Centers for Disease Control and Prevention (CDCs) in Guizhou's, informing future training and policy initiatives to strengthen public health responses.

Methods: A cross-sectional survey was conducted in August 2022, and an online, self-designed questionnaire on the Epidemiological Dynamic Data Collection platform was administered to evaluate the professional staff in CDCs. The responses were scored and presented using descriptive statistical methods, and the factors influencing the total score were analyzed by one-way ANOVA and linear regression.

MiR-18 regulates lipid metabolism of non-alcoholic fatty liver disease via IGF1.

We aimed to illustrate the regulatory effect of miR-18 on the onset of non-alcoholic fatty liver disease (NAFLD). MiR-18 level in liver tissues collected from NAFLD patients and mice was detected. In vivo and in vitro influences of miR-18 on biochemical indexes, glucose tolerance and insulin resistance (IR) in NAFLD were determined.

n-Acetylcysteine protects against diazinon-induced histopathological damage and apoptosis in renal tissue of rats.

Diazinon (DZN) is a member of organophosphorus insecticides that has cytotoxic effects on different organs. n-Acetyl cysteine (NAC) is a widely used antioxidant in clinical, in vivo and in vitro studies. We evaluated the protective role of NAC against DZN-induced toxicity in kidney tissue of Wistar rats.

Engraftment of adult hematopoietic stem and progenitor cells in a novel model of humanized mice.

Pre-clinical use of humanized mice transplanted with CD34 hematopoietic stem and progenitor cells (HSPCs) is limited by insufficient engraftment with adult non-mobilized HSPCs. Here, we developed a novel immunodeficient mice based on NOD-SCID- (NSG) mice to support long-term engraftment with human adult HSPCs. As both Flt3L and IL-6 are critical for many aspects of hematopoiesis, we knock-out mouse and knock-in human gene.

Silica monolayer isolation of electrodeposited SERS substrate and online probing of molecule adsorption onto mineral microparticles in relation to flotation.

In the minerals processing industry, the surface chemistry of mineral particles and its real-time detection can significantly enhance process performance, and ultimately leading to automotive and intelligent control. The adsorption of collector molecule onto bulk mineral specimens could be investigated with the help of shell-isolated nanoparticle enhanced Raman spectroscopy (SHINERS). However, this method is unsuitable for the online detection of particles fluid consisted of micro-sized chalcocite that encountered in industrial production processes.

Comprehensive bioinformation analysis of homeodomain-leucine zipper gene family and expression pattern of HD-Zip I under abiotic stress in Salix suchowensis.

Background: Homeodomain-leucine zipper (HD-Zip) transcription factors are plant-specific and play important roles in plant defense against environmental stresses. Identification and functional studies have been carried out in model plants such as rice, Arabidopsis thaliana, and poplar, but comprehensive analysis on the HD-Zip family of Salix suchowensis have not been reported.

Results: A total of 55 HD-Zip genes were identified in the willow genome, unevenly distributed on 18 chromosomes except for chromosome 19.

Inhibition of TAF1B impairs ribosome biosynthesis and suppresses cell proliferation in stomach adenocarcinoma through promoting c-MYC mRNA degradation.

Hyperactivation of ribosome biosynthesis (RiBi) is a hallmark of cancer, and targeting ribosome biogenesis has emerged as a potential therapeutic strategy. The depletion of , a major component of selectivity factor 1 (), disrupts the pre-initiation complex, preventing RNA polymerase I from binding ribosomal DNA and inhibiting the hyperactivation of RiBi. Here, we investigate the role of , in regulating RiBi and proliferation in stomach adenocarcinoma (STAD).