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[This corrects the article DOI: 10.3389/fimmu.2025.1591912.].
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http://dx.doi.org/10.3389/fimmu.2025.1659836 | DOI Listing |
Int J Surg
September 2025
Department of Urology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Background: The pathophysiological changes driving incident kidney cancer remain unclear. This study aimed to identify protein biomarkers and underlying mechanisms using pre-diagnostic plasma proteomics.
Materials And Methods: Among 48,851 UK Biobank participants, 165 were diagnosed with kidney cancer, and 2,911 plasma proteins were analyzed.
Clin Kidney J
September 2025
Department of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore, Rome, Italy.
Genome editing technologies, particularly clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9, have transformed biomedical research by enabling precise genetic modifications. Due to its efficiency, cost-effectiveness and versatility, CRISPR has been widely applied across various stages of research, from fundamental biological investigations in preclinical models to potential therapeutic interventions. In nephrology, CRISPR represents a groundbreaking tool for elucidating the molecular mechanisms underlying kidney diseases and developing innovative therapeutic approaches.
View Article and Find Full Text PDFRev Cardiovasc Med
August 2025
Cardiovascular Surgery Department, Ankara Bilkent City Hospital, 06800 Ankara, Turkey.
Background: This study aimed to investigate the performance of two versions of ChatGPT (o1 and 4o) in making decisions about coronary revascularization and to compare the recommendations of these versions with those of a multidisciplinary Heart Team. Moreover, the study aimed to assess whether the decisions generated by ChatGPT, based on the internal knowledge base of the system and clinical guidelines, align with expert recommendations in real-world coronary artery disease management. Given the increasing prevalence and processing capabilities of large language models, such as ChatGPT, this comparison offers insights into the potential applicability of these systems in complex clinical decision-making.
View Article and Find Full Text PDFAnn Bot
September 2025
National Museum, Prague, Czech Republic.
Background And Aims: Hornworts are rarely found in the fossil record, so each new find provides important insights regarding their evolution and diversity. Here we revisit a controversial genus, Notothylacites, described from the Late Cretaceous of Central Europe, which has liverwort morphology, but bears hornwort spores.
Methods: The fossil material was originally studied in 1970 by Pacltová using pollen preparation techniques.
J Vet Intern Med
September 2025
Department of Population Medicine, Ontario Veterinary College, University of Guelph, Ontario, Canada.
Background: Sudden cardiac death is common in racehorses. Factors associated with the QT interval that could predispose to fatal cardiac arrhythmias are unknown. Cardiac restitution, expressed as a ratio of QT/TQ, has been used in humans to assess arrhythmia risk but has not been described in horses during maximal intensity exercise.
View Article and Find Full Text PDF