Enhancing Domain Generalization in Medical Image Segmentation With Global and Local Prompts.

Enhancing domain generalization (DG) is a crucial and compelling research pursuit within the field of medical image segmentation, owing to the inherent heterogeneity observed in medical images. The recent success with large-scale pre-trained vision models (PVMs), such as Vision Transformer (ViT), inspires us to explore their application in this specific area. While a straightforward strategy involves fine-tuning the PVM using supervised signals from the source domains, this approach overlooks the domain shift issue and neglects the rich knowledge inherent in the instances themselves.

Graph Neural Network Driven Exploration of Non-Precious Metal Catalysts for Air-to-Ammonia Conversion.

Efficient ammonia production directly from the air with minimal energy consumption remains one of the most challenging and ambitious scientific goals. NHOH has proven to be a promising stable intermediate in producing NH, with the direct generation of NH from air achieved by coupling a continuous flow plasma reactor with an electrolyzer. However, the requirement of noble metal-doped Cu alloys as the cathode catalyst limits the scalability and cost-effectiveness of the coupled plasma-electrochemical system.

Electronic Structure Modulation Coupled with Vacancy Defect Engineering in FeCoNiCrV High-Entropy Alloy Electrocatalyst for Enhanced Oxygen Evolution Reaction.

Strategic engineering of composition and defects in high-entropy alloy (HEA) catalysts represents a critical frontier for advancing catalytic technologies, yet this synergistic approach remains underexplored in current materials research. In this study, a FeCoNiCrV HEA electrocatalyst was directly synthesized on flexible carbon cloth via filtered cathode vacuum arc deposition, where sacrificial dopants (Cr and V) were precisely integrated into a FeCoNi-based HEA matrix. The deliberate integration of Cr and V modulated the electronic structure of the catalyst.

Exploration of differential expression and biological significance of amino acid metabolism genes in osteoarthritis.

Background: Osteoarthritis (OA) is a widespread disorder affecting joints, recognized for cartilage wear and inflammatory responses, which substantially affects patients' quality of life. This research aim to discover amino acid metabolism-related differentially expressed genes (AAMRDEGs) and clarify their functions in OA pathogenesis.

Methods: Herein, we conducted an analysis of combined GEO datasets (GSE55457, GSE55235, and GSE12021), identifying 169 AAMRDEGs and indicating their importance in chondrocyte function and inflammation.

Modeling tumor relapse using proliferation tracing and ablation transgenic mouse.

Tumor relapse remains a significant obstacle to successful therapy. Preclinical animal models that accurately reflect tumor relapse in patients are urgently needed. Here, we employed a dual recombinase-mediated genetic system to genetically trace and ablate proliferating cells in a polyomavirus middle T antigen (PyMT)-induced spontaneous murine breast cancer model.

Winter Dormant Wheat Will Benefit From Mean Temperature Increase of 2°C When Well-Watered and Fertilized in the Main Producing Regions of China.

Rising temperatures are projected to lead to a decline in global wheat production. However, this global trend belies the regional nuances of this impact, such as observed local yield increases in some field experiments in the winter wheat-growing region of China. This study combines detailed data from eight field warming experiments and outputs of simulation by an ensemble of three point-based crop models and an ensemble of 10 global gridded crop models to scrutinize the influence of warming on winter wheat yield in the main producing regions of China (MPC).

Real-time emulation of leafy vegetables yield and quality response to 2 °C warming in northeast China.

Background: Vegetables provide essential parts of healthy, balanced diets in our daily life. Climatic warming is challenging the global vegetable productions, but realistic real-time evidences, especially in temperate regions, are still lacking. In this study, we developed two large, customized, fully artificial climate-controlled chambers capable of replicating the complexity of natural environmental fluctuations.

Research advance on vegetable growth models in China.

Vegetable growth models are crucial tools for predicting crop productivity under various environments. They could dynamically simulate the basic processes of vegetable growth and development, and also reflects the impact of different environmental factors and management practices on these processes. Foreign scholars have constructed vegetable growth models since the 1980s, including models of greenhouse cucumbers, tomatoes, bell peppers, onions, and other major vegetable crops.

The resistance risk of fluopicolide and resistance-associated point mutations in the target protein PlVHA-a in Phytophthora litchii.

Litchi, a fruit that is highly sought-after worldwide, faces significant yield challenges due to litchi downy blight, primarily caused by Phytophthora litchii. Fluopicolide has exhibited remarkable efficacy in inhibiting this pathogen and is utilized for the management of litchi downy blight. Although understanding the resistance of P.

Unveiling the critical role of surface adsorbed oxygen species for efficiently photothermocatalytic oxidation of VOCs: Replenishing the active surface lattice oxygen sites.

Surface oxygen species play a crucial role in the photothermocatalytic oxidation of volatile organic compounds (VOCs), but their exact functions and evolutionary processes remain unclear. Herein, a series of spinel CoMnO catalysts are synthesized and employed for photothermocatalytic oxidation of toluene. CoMnO catalysts achieve 91.

Insights from the international workshop on "Adapting agriculture to climate change and air pollution".

An international workshop on "Adapting Agriculture to Climate Change and Air Pollution" took place at Nanjing University of Information Science and Technology, Nanjing, China, during 23-27 October, 2023. Experts working in various multi-disciplinary areas of agroecosystem and environmental research gathered for academic communication and discussions. Two discussion groups focused on "agriculture under air pollution and climate change: current challenges and priorities for the future" and "adapting agriculture to air pollution and climate change: current status and next steps.

Resistance risk and resistance-associated point mutations in the target protein PcVHA-a of fluopimomide in Phytophthora capsici.

Fluopimomide, developed by Shandong Sino-Agri United Biotechnology Co., Ltd., is a pyridinylmethyl-benzamide fungicide with good activity against plant diseases caused by phytopathogenic oomycetes.

Mechanism for Adsorption, Dissociation, and Diffusion of Hydrogen in High-Entropy Alloy AlCrTiNiV: First-Principles Calculation.

To investigate hydrogen behaviors in the high-entropy alloy AlCrTiNiV, density functional theory and transition state theory were used to explore the molecular H2 absorption and dissociation and the atomic H adsorption, diffusion, and penetration progress. The H2 molecule, where the H-H band is parallel to the surface layer, is more inclined to absorb on the top site of the Ti atom site of first atomic layer on the AlCrTiNiV surface, then diffuse into the hollow sites, through the bridge site, after dissociating into two H atoms. Atomic H is more likely to be absorbed on the hollow site.

Climate-adaptive crop distribution can feed food demand, improve water scarcity, and reduce greenhouse gas emissions.

Optimizing crop distribution stands as a pivotal approach to climate change adaption, enhancing crop production sustainability, and has been recognized for its immense potential in ensuring food security while minimizing environmental impacts. Here, we developed a climate-adaptive framework to optimize the distribution of staple crops (i.e.

Potential benefits of cropping pattern change in the climate-sensitive regions of rice production in China.

Rice production is a primary contributor to global greenhouse gas emissions, with unclear pathways towards carbon neutrality. Here, through a comprehensive assessment of direct greenhouse gas (GHG) emission using DNDC model and indirect GHG emission using emission factor methods, we estimated the annual crop yield, GHG emission amount and intensity, and economic benefits of different cropping patterns in the climate-sensitive regions of rice production in China. Through the expansion of single-rice and cropping pattern change from the wheat-rice to wheat-rice-rice in the climate-sensitive regions of single and triple-cropping cultivations, the total grain yield increased by 4.

Sensitivity analysis and point mutations in BcSDHB confer cyclobutrifluram resistance in Botrytis cinerea from China.

Botrytis cinerea is one of the most destructive pathogens worldwide. It can damage over 200 crops, resulting in significant yield and quality losses. Cyclobutrifluram, a new generation of succinate dehydrogenase inhibitors, exhibits excellent inhibitory activity against B.

Identifying spatial variability of water chemical characteristics and groundwater discharge in Hulun Lake integrated remote sensing data and chemical components.

The frozen period interaction of groundwater and lakes is crucial for hydrological properties and aquatic ecology in cold and arid regions. In this study, we investigate the spatial hydrochemical characteristics, influencing factors in the Hulun Lake basin. The hydrochemical type of lake water exhibits Na-HCO-SO-Cl, while river shows a primary classification of Na-Ca-HCO.

Unveiling Vacuolar H-ATPase Subunit a as the Primary Target of the Pyridinylmethyl-Benzamide Fungicide, Fluopicolide.

An estimated 240 fungicides are presently in use, but the direct targets for the majority remain elusive, constraining fungicide development and efficient resistance monitoring. In this study, we found that knockout did not influence the sensitivity of to fluopicolide, which is a notable oomycete inhibitor. Using a combination of Bulk Segregant Analysis Sequencing and Drug Affinity Responsive Target Stability (DARTS) assays, the vacuolar H-ATPase subunit a (PcVHA-a) was pinpointed as the target protein of fluopicolide.

Experimental Study on Carbon Fiber-Reinforced Polymer Groove Machining by High-Power Water-Jet-Guided Laser.

Due to the excellent properties of carbon fiber-reinforced polymers (CFRPs), such as high strength and strong corrosion resistance, the traditional water-jet-guided laser (WJGL) technology has problems with fiber pull-out and has a small cutting depth when processing CFRPs. Therefore, in this study, we used high-power water-jet-guided laser (HPWJGL) technology to perform groove processing experiments on CFRPs. The effects of four key process parameters, high laser power, pulse frequency, feed rate, and water-jet pressure, on the cutting depth were investigated by a single-factor experiment.

Experimental Study on the Preparation of Ultra-Fine Brass Tube Electrodes by Ultrasonic Vibration.

In order to automatically process ultra-fine copper tube electrodes, this study proposes a new method of ultrasonic vibration processing of ultra-fine copper tube, analyzes its processing principle, designs a new set of experimental processing equipment and completes the processing of 1.206 mm inner diameter, 1.276 mm outer diameter with core brass tube.

Investigation of Spherical AlO Magnetic Abrasive Prepared by Novel Method for Finishing of the Inner Surface of Cobalt-Chromium Alloy Cardiovascular Stents Tube.

In this investigation, spherical AlO magnetic abrasive particles (MAPs) were used to polish the inner surface of ultra-fine long cobalt-chromium alloy cardiovascular stent tubes. The magnetic abrasives were prepared by combining plasma molten metal powder and hard abrasives, and the magnetic abrasives prepared by this new method are characterized by high sphericity, narrow particle size distribution range, long life, and good economic value. Firstly, the spherical AlO magnetic abrasives were prepared by the new method; secondly, the polishing machine for the inner surface of the ultra-fine long cardiovascular stent tubes was developed; finally, the influence laws of spindle speed, magnetic pole speed, MAP filling quantities, the magnetic pole gap on the surface roughness (Ra), and the removal thickness (RT) of tubes were investigated.

Modeling and Prediction of Water-Jet-Guided Laser Cutting Depth for Inconel 718 Material Using Response Surface Methodology.

In this study, the water-jet-guided laser (WJGL) method was used to cut Inconel 718 alloy with high temperature resistance. The effect of critical parameters of the water-jet-guided laser machining method on the cutting depth was studied by a Taguchi orthogonal experiment. Furthermore, the mathematical prediction model of cutting depth was established by the response surface method (RSM).