Characterization of fatty acid biosynthesis in microalga Scenedesmus - from the perspective of biofuel production.

Scenedesmus quadricauda, a freshwater microalga, has gained attention for its high lipid accumulation potential. However, information on fatty acid (FA) biosynthesis pathways in Scenedesmus species remains limited. Biomass (1.

Nicorandil in preventing contrast-induced nephropathy in patients undergoing cardiac catheterization procedures: a systematic review and meta-analysis.

Background: Contrast-induced nephropathy (CIN) remains a significant complication in patients undergoing coronary angiography (CAG) and percutaneous coronary intervention (PCI).

Methods: A comprehensive literature search was conducted across PubMed, MEDLINE, Embase, Google Scholar, and Web of Science up to May 2024 to identify randomized controlled trials (RCTs) evaluating the efficacy and safety of nicorandil in patients undergoing CAG or PCI. The primary outcome was CIN incidence, while secondary outcomes included, changes in serum creatinine, serum cystatin C, blood urea nitrogen (BUN), and estimated glomerular filtration rate (eGFR).

Comprehensive analysis of genomic loci associated with glaucousness in wheat ( L.) through Genome-wide association study.

Unlabelled: Wheat ( L.) is one of the most important cultivated cereal grain crop. The yield and productivity of wheat are profoundly affected by abiotic stresses like drought.

Role of lysophosphatidic acid in the regulation of immune cells and hematological malignancies.

Lysophosphatidic acid (LPA), a small bioactive glycerophospholipid, has been reported to play an indispensable role in the regulation of a wide range of cellular processes, including cell proliferation, morphology, differentiation, invasion, migration, and apoptosis. Besides, it has a diverse role in the development, differentiation, migration, and trafficking of immune cells. The role of LPA in the functioning of immune cells, such as macrophages, natural killer cells, T cells, and B cells has been poorly understood and is still a major thrust area for immunological research.

Circular RNAs Binding to RNA-Binding Proteins.

High-throughput RNA sequencing yields novel noncoding RNAs called circular RNAs (circRNAs). They are extensively distributed across the transcriptomes of humans and other metazoans. Research has demonstrated their critical functions in multiple cellular developmental processes and diseases, including cancer, cognitive disorders, and neurodegenerative disorders (NDDs).

QT interval prolongation in schizophrenia: A cross-sectional study from a tertiary care center in Raipur.

Background & objectives Antipsychotic drugs can cause QT interval prolongation (QTIP), which can lead to life-threatening cardiac manifestations. The objective of this study was to find out the prevalence of QTIP in stable patients of schizophrenia attending the outpatient department/clinic. Methods A total of 88 consenting individuals with schizophrenia aged ≥18 yr of either sex (male or female), who were stable on treatment and adherent to the prescribed medications, were included.

To Substitute Rather Than Intercalate: Approach to Induce Ferromagnetism in Metastable PtSe ( = Cr, Co, Ni).

Two-dimensional (2D) magnetic materials with exotic magnetic properties have garnered significant interest due to their potential applications in spintronics and data storage technologies. However, the limited availability of intrinsic 2D magnetic materials has driven efforts to induce and manipulate magnetism in otherwise nonmagnetic 2D systems through approaches such as chemical intercalation, defect engineering, and substitutional doping. Herein, we present a facile, method for incorporating 3 transition metals (Cr, Co, and Ni) into the nonmagnetic PtSe sublattice.

The role of bioavailable inhibin B in predicting oocyte yield in expected poor responders: the forgotten marker?

Background: Inhibin B (InhB) is secreted by granulosa cells and reflects early follicular activity. While anti-Müllerian hormone (AMH) and antral follicle count (AFC) are established ovarian reserve markers, the role of bioavailable inhibin B (bio-InhB) in predicting oocyte yield remains uncertain. This is particularly relevant in women with low ovarian reserve, where reliable prediction of ovarian response is clinically important.

QT interval prolongation from antipsychotics in schizophrenia and acute psychosis - A prospective study.

Background: Antipsychotic drugs have the potential to cause QT-interval prolongation (QTIP), which may lead to Torsades de Pointes and sudden cardiac death. Thus, it is important to know about the incidence and risk factors for QTIP.

Aim: The primary objective of the study was to find out the incidence of QTIP due to the use of antipsychotic drugs in patients with schizophrenia and acute psychosis after two weeks of drug use.

Predicting water quality index using stacked ensemble regression and SHAP based explainable artificial intelligence.

Effective forecasting of the Water Quality Index (WQI) considerably impacts water resource management as well as public health safety. This study proposes a new approach for WQI forecasting using stacked regression ensemble modeling integrated with SHAP (Shapley Additive explanations), a form of Explainable Artificial Intelligence (XAI). The model was developed using a dataset of 1,987 water quality samples from Indian rivers (2005-2014), processed through six optimized machine learning algorithms: XGBoost, CatBoost, Random Forest, Gradient Boosting, Extra Trees, and AdaBoost, combined using Linear Regression as the meta-learner.

Molecular Characterization of Steroid 5 Alpha-Reductase 2 (SRD5A2) Gene Variant in Indian Patients with Disorder of Sexual Development.

The 5 alpha-reductase deficiency is one of the significant causes of the disorders of sex development (DSD) in individuals bearing 46 XY chromosomes. The conversion of testosterone into dihydrotestosterone is impaired on account of this enzyme deficiency. The mutations in the steroid 5 alpha-reductase type 2 gene (SRD5A2) result in the deficiency of this enzyme.

Development of a composite core collection from 5,856 Sesame accessions being conserved in the Indian National Genebank.

Objectives: A composite core collection (CCC) in sesame (Sesamum indicum L.) will help utilize genetic resources efficiently. This study reports, using genomics tools, a representative minimal set (CCC) that capture maximal genetic diversity from a set of 5,856 sesame accessions being conserved at the National Genebank (NGB) of the ICAR-NBPGR.

Knowledge and practice on oral hygiene maintenance among medical students in India.

Oral hygiene is vital in preventing dental caries, periodontal diseases and systemic conditions like stroke and heart disease. Therefore, it is of interest to evaluate oral health awareness among MBBS students and interns using a pretested, structured questionnaire. Data analysis was performed using the Chi-square test with a significance threshold of 0.

Periodontal and microbiological evaluation in cleft lip/palate patients undergoing orthodontic treatment: An study.

Periodontal and microbiological characteristic among cleft lip and/or palate patients undergoing fixed orthodontic treatment is of interest. Plaque and saliva samples showed high prevalence of (83%), (67%), and (55%). analysis showed significantly greater biofilm formation on stainless steel brackets compared to ceramic brackets (p < 0.

Role of full-thickness skin grafts in post-maxillectomy rehabilitation.

The importance of full thickness skin graft for reconstruction or Rehabilitation after Maxillectomy and mid face defect is well known. In this study we included 50 patients who underwent maxillectomy due to cancer of the mid-face and had full-thickness skin graft reconstruction. Based on the clinical examination and the subjective assessment of patients, a positive effect of the use of free skin grafts on their convalescence and rehabilitation was found.

Efficacy of colchicine in oral submucous fibrosis: A systematic review and meta-analysis.

One of the potentially malignant disorders of the oral mucosa in Asian nations is known as oral submucous fibrosis (OSMF). The drug, surgical and combination therapies are some of the several OSMF treatment options. The importance of colchicine in the treatment of oral submucous fibrosis is still unclear.

Mapping antimicrobial susceptibility of community-acquired uropathogenic Escherichia coli across low, middle and high-income countries highlights significant differences: insights for empiric treatment.

Objectives: Rising antimicrobial resistance (AMR) in urinary tract infections (UTI) poses a global challenge. Evidence-based treatment of cystitis requires local resistance data. The DASH to Protect Antibiotics (https://dashuti.

Unveiling genomic diversity of glycolipid transfer protein (GLTP) gene family in rice: The lipid connection to climate resilience.

Glycolipid transfer protein (GLTP) genes are recognized for their role in stress adaptation in animals. In this study, for the first time, seventy-four GLTP genes were identified across ten Oryza species, with each species containing 6-9 genes. These genes exhibited strong synteny and collinearity, maintaining conserved chromosomal positions across all Oryza species.

Underwater image enhancement using hybrid transformers and evolutionary particle swarm optimization.

Underwater imaging is a complex task due to inherent challenges such as limited visibility, color distortion, and light scattering in the water medium. To address these issues and enhance underwater image quality, this research presents a novel framework based on a Hybrid Transformer Network optimized using Particle Swarm Optimization (HTN-PSO). The HTN-PSO framework combines the strengths of convolutional neural networks and transformer models to effectively capture low-level features and model long-range dependencies.

Absence of Deep and Basal Veins Is Common and Clinically Relevant in Sturge-Weber Syndrome.

Background: Common intracranial vascular abnormalities in Sturge-Weber syndrome (SWS) include leptomeningeal venous malformations (LVMs) and enlarged deep veins. A few small studies have reported absent deep veins in some patients. We used susceptibility-weighted imaging (SWI), a magnetic resonance imaging (MRI) sequence sensitive to detecting small veins, to evaluate deep cerebral veins and the basal vein of Rosenthal (BVR) and assess the radiological correlates and clinical impact of their absence.

SPD_1629 is a uracil transporter and is crucial for pneumococcal fitness and pathogenesis in vivo.

Streptococcus pneumoniae (pneumococcus), a major human pathogen, causes pneumonia, bacteraemia and meningitis. Unlike free-living bacteria such as Escherichia coli, pathogenic bacteria like S. pneumoniae possess incomplete metabolic pathways and depend on host-derived nutrients.

Comparison of repetitive peripheral magnetic stimulation (rPMS) and sham-rPMS with supervised exercise on pain and function in knee osteoarthritis patients -protocol for randomized sham-controlled trial.

Background: Knee Osteoarthritis (KOA) is a degenerative joint condition that impairs patient's quality of life and work productivity. Pharmacological management has been found to provide short-term symptomatic relief with adverse effects, whereas physical therapy has been recommended by guidelines as a prime treatment approach. The objective is to evaluate the effectiveness of repetitive peripheral magnetic stimulation (rPMS) in the treatment of KOA.

Role of diosgenin in gastrointestinal cancers: recent trends and future perspectives.

Gastrointestinal cancers represent a considerable global public health burden, due to their high incidence, poor prognosis, and resistance to conventional therapies. Traditional treatments like chemotherapy and radiation often produce side effects and limited efficacy, making targeted therapies even more necessary. Diosgenin, a naturally steroidal saponin found in Dioscorea species, has gained widespread acclaim as an anticancer agent due to its anti-inflammatory, antioxidant, and cancer-fighting properties.

Numerical Investigation of Buckling Behavior of MWCNT-Reinforced Composite Plates.

The current study demonstrates the buckling properties of composite laminates reinforced with MWCNT fillers using a novel higher-order shear and normal deformation theory (HSNDT), which considers the effect of thickness in its mathematical formulation. The hybrid HSNDT combines polynomial and hyperbolic functions that ensure the parabolic shear stress profile and zero shear stress boundary condition at the upper and lower surface of the plate, hence removing the need for a shear correction factor. The plate is made up of carbon fiber bounded together with polymer resin matrix reinforced with MWCNT fibers.