Controlled Silver Nanoparticle Formation in Hair Fibers Dyed with L.: A Study on Additive-Dependent Penetration and Aggregation.

Applying physico-analytical methods to whole hair fibers enables investigation of hair dye performance. Light microscopy, SEM imaging and EDX mapping of intact hair fibers, as well as TEM imaging of microtome cuts, provided insights into the distribution, size, shape and growth patterns of the dyeing species and particles, thus demonstrating the correlation between silver nanoparticles (AgNPs) and dye impression. Yak hair fibers were treated with a polyphenol-containing L.

Ubiquitination Regulates Reorganization of the Membrane System During Cytomegalovirus Infection.

Background: During infection with the cytomegalovirus (CMV), the membrane system of the infected cell is remodelled into a megastructure called the assembly compartment (AC). These extensive changes may involve the manipulation of the host cell proteome by targeting a pleiotropic function of the cell such as ubiquitination (Ub). In this study, we investigate whether the Ub system is required for the establishment and maintenance of the AC in murine CMV (MCMV)-infected cells Methods: NIH3T3 cells were infected with wild-type and recombinant MCMVs and the Ub system was inhibited with PYR-41.

Correction: Kalisvaart et al. Relative Wash-In Rate in Dynamic Contrast-Enhanced Magnetic Resonance Imaging as a New Prognostic Biomarker for Event-Free Survival in 82 Patients with Osteosarcoma: A Multicenter Study. 2024, , 1954.

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Late enhancement and wash-out maps for differentiation of glioblastoma and metastases.

Background: Advanced MR imaging methods, such as perfusion, spectroscopy and diffusion-weighted imaging (DWI), help to distinguish between different types of brain tumors. We have established a rapid wash-out and late-enhancement map in our clinic. The aim of our study was to evaluate the potential usefulness of this map for the initial diagnosis.

Topological and Reconfigurable Terahertz Metadevices.

The terahertz (THz) frequency range, situated between microwave and infrared radiation, has emerged as a pivotal domain with broad applications in high-speed communication, imaging, sensing, and biosensing. The development of topological THz metadevices represents a notable advancement for photonic technologies, leveraging the distinctive electronic properties and quantum-inspired phenomena inherent to topological materials. These devices enable robust waveguiding capabilities, positioning them as critical components for on-chip data transfer and photonic integrated circuits, particularly within emerging 6G communication frameworks.

A prospective study of efficacy and safety of Kahook Dual Blade (KDB) glide in Indian patients with glaucoma.

Purpose: To assess the success rate and complications of Kahook Dual Blade (KDB) procedure in Indian patients diagnosed with glaucoma.

Methods: This prospective study was done on 68 Indian patients who underwent KDB procedure combined with phacoemulsification. Baseline demographic and clinical characteristics were recorded, including visual acuity, intraocular pressure (IOP), number of anti-glaucoma medications (AGM), and complications.

Assessment of contamination risk across different environmental media in rural Ethiopia.

pathotypes, particularly enteropathogenic and enterotoxigenic strains, are among the leading causes of moderate-to-severe diarrhea in low- and middle-income countries (LMICs). These pathogens are commonly transmitted through environmental media such as contaminated water, soil, and hands, often due to poor sanitation and hygiene. In this first phase of an ongoing longitudinal study, we conducted a cross-sectional assessment of contamination across multiple environmental compartments in 41 rural households in Daro Lebu Woreda, West Hararghe Zone, Eastern Ethiopia.

Sustainable hydrophobic modification of cotton with rosemary wax extracted by supercritical CO₂ explored through DFT analysis.

The present study focuses on the functionalization of cellulose-based textiles with residual rosemary wax, a by-product of supercritical CO₂ extraction of essential oil. The main objectives of this study were to identify the chemical composition of rosemary wax using FTIR, GC-MS, and HPLC techniques, to optimize its application onto cellulose fabrics, and to evaluate the properties of the treated textiles fabrics. In order to verify the efficacy of the treatment, a series of tests were carried out.

Setting Factors Associated With Licensed Psychotherapists' Interest in the Implementation of Electroencephalogram Neurofeedback Into Practice.

Neurofeedback has been utilized to treat a variety of mental health issues by influencing brainwave patterns using auditory and/or visual feedback. Despite a plethora of research, there is a significant gap regarding why neurofeedback is not more commonly utilized in mental health care practice. This study sought to address this gap by posing the question: ' This study utilized the Consolidated Framework for Implementation Research to explore factors associated with outpatient psychotherapists' interest in implementing neurofeedback in their practices.

In situ exogenous alpha-synuclein aggregates inhibit murine ventricular voltage-gated inward sodium and outward potassium currents.

BackgroundAlpha-synuclein is associated with neurodegeneration in Parkinson's disease (PD). Recent studies have increasingly recognized incidences of cardiac complaints in PD patients. In particular, the occurrence of arrhythmias in PD patients may indicate potential electrophysiological alterations in the heart.

Identification of Critical States in Complex Biological Systems Using Cell-Specific Causal Network Entropy.

Abrupt shifts, referred to as critical transitions, are frequently observed in complex biological systems, characterized by marked qualitative changes occurring from one stable state to another through a pre-transitional/critical state. Pinpointing such critical states, along with the signaling molecules, can provide valuable insights into the fundamental mechanisms of intricate biological processes. However, the identification and early warning of the critical state remains a challenge, particularly in model-free cases with high-dimensional single-cell data, where traditional statistical methods often prove inadequate due to the inherent sparsity, noise, and heterogeneity of the data.

The Mathematical Foundation of Post-Quantum Cryptography.

In 1994, P. Shor discovered quantum algorithms that can break both the RSA cryptosystem and the ElGamal cryptosystem. In 2007, a Canadian company D-Wave demonstrated the first quantum computer.

Analysis of dynamic contrast-enhanced T1-weighted imaging parameters in type II TIC breast lesions.

Background: In dynamic contrast-enhanced T1-weighted imaging (DCE-T1WI) of breast lesions, type III time-intensity curves (TICs) are associated with malignant lesions, and type I TICs are associated with benign lesions, but the association of type II curves with the status of breast lesions remains controversial. This study aimed to analyze the semi-quantitative parameters derived from DCE-T1WI in patients with type II TIC breast lesions and to develop a nomogram for the benign/malignant classification of lesions with type II TICs.

Methods: Data of patients with type II TIC breast lesions were retrospectively collected.

Factors influencing menstrual hygiene knowledge, attitudes, and practices among adolescent girls in African rural schools: scoping review.

Menstrual hygiene management (MHM) is a critical component of adolescent health and well-being, particularly in rural African schools where cultural, economic, and infrastructural challenges persist. This scoping review followed the steps proposed by Arksey and O'Malley to explore the factors influencing menstrual hygiene knowledge, attitudes, and practices among adolescent girls in rural African settings. The review systematically analysed literature conducted in diverse African rural public schools.

Functional Compression Fabrics with Dual Scar-Suppressing and Antimicrobial Properties: Microencapsulation Design and Performance Evaluation.

Pressure therapy combined with silicone has a significant effect on scar hyperplasia, but limitations such as long-term wearing of compression garments (CGs) can easily cause bacterial infection, cleanliness, and lifespan problems of CGs caused by the tedious operation of applying silicone. In this study, a compression garment fabric (CGF) with both inhibition of scar hyperplasia and antibacterial function was prepared. A polydimethylsiloxane (PDMS)-loaded microcapsule (PDMS-M) was prepared with chitosan quaternary ammonium salt (HACC) and sodium alginate (SA) as wall materials and PDMS as core materials by the complex coagulation method.

Crisis, Confidence, and Conserving Resources: Examining How Adult Education Students Navigate Stressors and Marginalization.

Social and systemic barriers contribute to students' attrition from K-12 education and enrollment in adult basic education (ABE) via the reduction of available resources. Informed by Conservation of Resources Theory, the current study assessed the impact of stress-related risk factors, including trauma and COVID-19-related stress, on ABE students' ( = 227) vocational confidence. Understanding these factors can inform ABE program development and retention efforts.

AMPK-ULK1-Mediated Ferritinophagy Drives Ferroptosis in GLA-Induced Testicular Toxicity.

The health problem of infertility has garnered increasing attention, prompting a deeper understanding of its causes. The broad-spectrum and nonselective herbicide glufosinate ammonium (GLA) is widely used in many countries. Previous studies have demonstrated the reproductive toxicity of GLA, but its potential toxic mechanisms remain unclear.

Gpr35 Expression Mitigates Neuroinflammation and Enriches Gut to Relieve Parkinson's Disease.

Parkinson's disease (PD) is associated with gut-brain axis and gut microbiota alterations, but the functioning mechanism remains to be elucidated. In this study, we identified G protein-coupled receptor 35 (Gpr35) as a key regulator for the gut-brain association under the PD context. It investigated the impact of Gpr35 deficiency on motor function, neuroinflammation, and dopaminergic neurodegeneration, using the Gpr35 knockout (Gpr35) and wild-type (WT) mice in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced PD model, and Gpr35 up-/down-regulation on reverse neuroinflammation, oxidative stress, and neuronal apoptosis using Gpr35 agonist kynurenic acid (KYNA) and small interfering RNA in microglial and dopaminergic cell models.

Lignin Unlocks Stealth Carbon Sinks in Cold Seeps via Microbial Enzymatic Gatekeeping.

Cold seep ecosystems serve as critical hubs in marine carbon cycling through methane emissions and organic matter processing. While terrestrial lignin constitutes a major fraction of persistent organic carbon in cold seep sediments, its microbial transformation pathways in deep-sea cold seep environments remain unexplored. Here, we present the first comprehensive analysis of lignin distribution across sediment horizons at the Haima cold seep, coupled with a multi-omics investigation of microbial lignin metabolism.

Ab Initio Accuracy Neural Network Potential for Drug-Like Molecules.

The advent of machine learning (ML) in computational chemistry heralds a transformative approach to one of the quintessential challenges in computer-aided drug design (CADD): the accurate and cost-effective calculation of atomic interactions. By leveraging a neural network (NN) potential, we address this balance and push the boundaries of the NN potential's representational capacity. Our work details the development of a robust general-purpose NN potential, architected on the framework of DPA-2, a deep learning potential with attention, which demonstrates remarkable fidelity in replicating the interatomic potential energy surface for drug-like molecules comprising 8 critical chemical elements: H, C, N, O, F, S, Cl, and P.

RoadDiffBox: Automatic Road Distress Diagnosis through Controlled Image Generation and Semi-Supervised Learning.

During the designed service life, road infrastructures will bear repeated loading conditions from vehicle weights and environmental conditions, resulting in the inevitable occurrence of road distresses including cracks, potholes, etc. The traditional inspection methods by transportation engineers are normally costly and labor-intensive. In recent years, artificial intelligence (AI)-based road distress detection methods have been widely used as convenient and automated approaches, while the AI-based methods heavily depend on a large amount of high-quality images, limiting the real engineering applications.

Targeting the ANXA8-SP1-PPA1 Axis to Modulate TCA Cycle and Matrix Deposition in Diffuse-Type Gastric Cancer.

Diffuse-type gastric cancer (DGC) is an aggressive tumor type characterized by a dense extracellular matrix (ECM). Metabolic reprogramming, a key oncogenic factor driving tumor progression, is closely linked to ECM deposition, although the regulatory mechanisms remain poorly understood. In this study, we integrated single-cell sequencing, proteomics, metabolomics, and large-scale clinical data to identify the metabolic signature of DGC.

Analysis of compliance issues and influencing factors in the management of BSL-2 laboratories for pathogenic microorganisms in Lishui, China.

Background: The management of biosafety laboratories for pathogenic microorganisms is directly related to public health and the effectiveness of biological experiments. However, persistent non-compliance issues in biosafety level 2 (BSL-2) laboratory management remain a challenge. This study aimed to assess the quality control of BSL-2 laboratories for pathogenic microorganisms in Lishui.

Tooth preparation-related factors that impact the accuracy of intraoral scanners for fabricating tooth-supported restorations: A systematic review.

Statement Of Problem: A systematic evaluation regarding the tooth preparation-related factors that impact the accuracy of intraoral scanners (IOSs) is lacking.

Purpose: The purpose of this systematic review was to examine the tooth preparation-related factors that impact the IOS accuracy for fabricating tooth-supported restorations.

Material And Methods: A literature search was completed in 5 databases: PubMed/Medline, Scopus, Embase, World of Science, and Cochrane.