Race, Ethnicity, Insurance Payer, and Pediatric Cardiac Arrest Survival.

Importance: Lower survival rates among Black adults relative to White adults after in-hospital cardiac arrest are well-described, but these findings have not been consistently replicated in pediatric studies.

Objective: To use a large, national, population-based inpatient database to evaluate the associations between in-hospital mortality in children receiving cardiopulmonary resuscitation (CPR) and patient race or ethnicity, patient insurance status, and the treating hospital's proportion of Black and publicly insured patients.

Design, Setting, And Participants: This retrospective population-based cohort study used the Healthcare Cost and Utilization Project Kids' Inpatient Database (1997-2019 triennial versions).

Moral Intelligence: Construction of a Moral Intelligence Scale Developed in Poland.

Moral intelligence is the ability to distinguish between right and wrong, to make ethical decisions, and to be guided by certain values in life. In view of cultural and social change and the ongoing crisis of values, moral intelligence is of particular importance today in various areas of human life and function. The purpose of this article is to introduce the topic of moral intelligence and its operationalization in order to construct the moral intelligence scale.

Manganese catalyzed cross-coupling of allylic alcohols and indoles: an elegant route for access to γ-hydroxyindole.

Alcohol and indole derivatives are widely recognized as versatile building blocks in both chemical and biochemical synthesis. The formal conjugate addition between these two classes of compounds provides a powerful and sustainable strategy for constructing γ-hydroxyindoles, owing to the reaction's 100% atom economy and the ready availability of starting materials. In this study, we report a redox-neutral cross-coupling reaction between indoles and allylic alcohols, catalyzed by a manganese(i) pincer complex, which enables the efficient synthesis of a broad range of γ-hydroxyindoles under mild conditions.

The positive effect of moral self-concept on fraudulent behavior and the need for moral cleansing.

Both moral cleansing and moral licensing theories suggest that moral self-concept positively influences subsequent engagement in fraudulent behavior. Specifically, a decrease in moral self-concept reduces dishonesty (moral cleansing), while an increase promotes it (moral licensing). However, within these theoretical frameworks, prior research has rarely measured moral self-concept directly, and even fewer studies have manipulated it experimentally.

Adenosine Concentration Determination for Tumor Microenvironment Simulation.

Objectives: We aimed to investigate the concentration of adenosine (ADO) in the tumor microenvironment (TME), focusing on its potential to modulate tumor cells and natural killer (NK) cells, thereby facilitating tumor immune escape.

Methods: In this study, an in vitro simulation system was developed to systematically evaluate the effects of ADO (0-500 μM) on the colony formation and migration capability of A549 (lung carcinoma) and A375 (melanoma) cell lines, as well as its action on NK92 cell activity, cytokine secretion, and cytotoxicity against tumor cells.

Results: The results showed that 50 μM ADO significantly promoted tumor cell proliferation (increasing the colony formation rate by 60%-80%) and migration (increasing the migration rate by 30%-40%), whereas high concentrations (>200 μM) exhibited an inhibitory effect.

Grandiose narcissism, leadership, and workplace deviance: does self-interest always breed toxicity in leadership roles?

Background: Existing literature on leader narcissism reveals conflicting evidence due to the paradoxical nature of narcissistic traits- narcissistic admiration and rivalry. Additionally, a bipolar view of self-interest, rooted in the concept of dual behavior may help in clarifying this paradox. Therefore, the study examines how narcissistic admiration and rivalry affect leader narcissism and workplace deviance, with self-interested behavior acting as a mediating factor.

Exploring the change management framework: An in-depth investigation.

Change management is part of Software Development Life Cycle (SDLC), particularly during the challenging stage of Requirement Engineering (RE). Managing requirements and incorporating changes can be complex and demanding, Having high impacts on project duration, cost, and ultimately project success and failure, cost, and ultimately, the success or failure of the software project. This research paper aims to explore and analyses various change management frameworks that contribute to the effectiveness of project completion, with a focus on minimizing time and cost estimates while maximizing product quality.

The 2023 European Commission proposal and the 2024 European Parliament proposal for the EU pharmaceutical legislation: policy content analysis.

A revision of the pharmaceutical legislation is ongoing at the European Level. The European Commission proposed a first draft in April 2023, and the European Parliament has adopted a position on the proposal in April 2024. The proposal consists of a new Directive and a new Regulation, with the aim of integrating different provisions that have been introduced over time.

Prediction premenstrual syndrome (PMS) with anxiety, and depression in female students.

Background: Premenstrual syndrome (PMS) is a prevalent and multifaceted disorder affecting women of childbearing age, characterized by emotional, physical, and behavioral symptoms. The psychological dimensions, particularly anxiety and depression, exacerbate the burden of PMS. This research aimed to find predictive factors of PMS using ordinal logistic regression models (OLR).

Development and validation of a competency-based ladder pathway for AI literacy enhancement among higher vocational students.

The rapid integration of artificial intelligence across industries necessitates systematic AI literacy development in higher vocational education to prepare students for AI-driven professional environments. This study develops and validates a comprehensive competency-based ladder development pathway specifically designed to enhance AI literacy among vocational students. The research employs a mixed-methods approach combining theoretical framework construction, empirical investigation, and practical implementation validation.

Evaluating Inflorescence Morphology in Two Species and Subspecies of the Genus R. Brown.

(1) The primary objective was to determine whether, within this taxonomically challenging group, the closely related European species and their subspecies exhibit distinct inflorescence characters that allow for unambiguous differentiation. This study focuses on two closely related species within the genus : (Schrank) Borbás and (L.) Beauv.

Development and validation of a hypoxia-immune-based microenvironment gene signature for predicting survival in non-small cell lung cancer.

Background: This study aims to establish a hypoxia-immune-related gene signature within the tumor microenvironment (TME) to reliably predict prognosis in non-small cell lung cancer (NSCLC).

Methods: Transcriptomic profiles and clinical data of lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) were obtained from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases (GSE74777, GSE68465). Hypoxia- and immune-related genes were curated from MSigDB, ImmPort, and INATDB.

Mortality among patients with multiple sclerosis in Poland.

Background: Mortality studies in patients with multiple sclerosis (MS) are scarce. We aimed to investigate all-cause MS mortality in a large cohort from Poland and to compare it with the general Polish population METHODS: The annual mortality data (2002-2022) for all patients with MS who died in Poland were obtained from Statistics Poland. Mortality in MS compared with the general population was examined using the Standardized Mortality Ratio (SMR) and Excess Death Rates (EDR).

Heterogeneous impacts of climate change on morbidity.

This paper examines the effect of temperature on emergency department (ED) visits using administrative data covering 50 % of the Hungarian population and 3.52 million ED visits from 2009 to 2017. The results show that ED visit rates increase when average temperatures exceed 10°C, primarily driven by mild cases that do not result in hospitalization.

Trends and Directions of Preference Elicitation and Assessment in Food Science: Single-, Pair-, and Multi-Criteria Ranking Methods.

Different ranking methods have long been used in sensory testing. Their diffusion was mainly due to their simplicity, their standardized methods, their software support, and their wide range of applications. However, a number of research and industrial problems have emerged recently that cannot be adequately solved by the standard approaches, making it necessary to apply and adapt methods from other disciplines.

Development of a Clostridium Perfringens Challenge Model in Broiler Chickens to Evaluate the Effects of Feed Additives.

Necrotic enteritis, caused by () is a disease present worldwide and causes major economic losses. The re-emergence of the disease, in recent years, is mainly due to the ban of the usage of antibiotics as growth promoters in the EU. The aim of this study was to establish a reliable, robust challenge model.

Influence of socioeconomic status on children's reading abilities: the mediating role of home learning environment and the moderating role of grade level.

Family socioeconomic status (SES) has been shown to be associated with children's academic abilities. However, how SES influences children's reading abilities across grades still warrants investigation. This study recruited 1st - through 6th -grade children (N = 1,534) and examined the role of Home Learning Environment in the relationship between SES and reading abilities.

Entropy in the Assessment of the Labour Market Situation in the Context of the Survival Analysis Methods.

Since Shannon's pioneering work, the concept of entropy has been used in many major scientific fields. It is therefore a universal concept but also defined in different ways. Entropy is used in studies of system complexity and to investigate the information content of probability distributions.

Application of multi-stage fracturing stimulation based on case study of Chang-7 shale gas formation in Ordos basin.

To address the issue of low production output, additional stimulation measures are always adopted.This study analyzes the complex characteristics of the Chang-7 shale gas reservoir in the central Tianhuan Syncline, Ordos Basin. Facing challenges from reservoir heterogeneity, we implemented a multi-stage fracturing pilot in the first horizontal well (DPX) of the Chang-7 reservoir using drillable bridge plug technology and customized fracturing designs based on horizontal well multi-stage stimulation theory and multi-fracture interference mechanisms.

Soil nitrogen drives inverse acclimation of xylem growth cessation to rising temperature in Northern Hemisphere conifers.

Controlled experiments suggest that the seasonal build-up of nitrogen (N) limitation constrains the responses of forest autumn phenology to elevated temperatures. Therefore, rising soil N is expected to increase the delaying effects of elevated temperature on the end of the season, i.e.

Made in China 2025: Artificial intelligence intervention and urban green economy development.

Against the backdrop of the profound adjustment of the global industrial structure and the rise of the Fourth Industrial Revolution, the contradiction between rapid economic growth and ecological environmental protection has become increasingly prominent. Promoting green development has become a key path to achieving sustainable urban development. In 2015, China launched the "Made in China (2025)″ policy, aiming to promote industrial transformation and upgrading through intelligent manufacturing and green production.

Screen-based sedentary behavior and BMI among Chinese adolescents: weight concern as a mediator moderated by body image perception.

Objective: Screen-based sedentary behavior (SB) is associated with elevated BMI; however, the underlying mechanisms remain poorly understood. This study investigates the mediating role of weight concern in the SB-BMI relationship and examines how body image perception and gender moderate this mediation. By focusing on body image as a critical contextual factor, the study aims to inform targeted interventions for adolescent obesity and overweight.

Effects of blood flow restriction training on aerobic capacity and performance in endurance athletes: a systematic review and meta-analysis.

Background: Although blood flow restriction (BFR) training has been increasingly investigated for its potential to enhance aerobic capacity and performance in endurance athletes, its overall effectiveness remains inconclusive. This systematic review and meta-analysis aimed to evaluate the impact of BFR training on aerobic capacity, muscle strength, and endurance performance in endurance athletes compared to the same training without BFR.

Methodology: Databases searched included PubMed, Scopus, Web of Science, and SPORTDiscus through September 2024.

Heterologous expression of the plant defensin SmD1 in .

SmD1 isolated from seeds of common chickweed has strong inhibitory activity against phytopathogenic fungi and oomycetes in the micromolar range (IC ≤ 1 μM). However, the low production of plant defensins in natural strains limits their large-scale actual production. In this study, defensin gene was successfully heterologously expressed in BL21 (DE3) for efficient production of plant defensins.