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To address the issue of low production output, additional stimulation measures are always adopted.This study analyzes the complex characteristics of the Chang-7 shale gas reservoir in the central Tianhuan Syncline, Ordos Basin. Facing challenges from reservoir heterogeneity, we implemented a multi-stage fracturing pilot in the first horizontal well (DPX) of the Chang-7 reservoir using drillable bridge plug technology and customized fracturing designs based on horizontal well multi-stage stimulation theory and multi-fracture interference mechanisms. Research shows: Fracture parameters (stage count, geometry, length) and operational parameters (perforation scheme, fracturing scale, fluid type, injection rate) designed according to overall reservoir characteristics are significantly affected by heterogeneity during implementation, resulting in substantial variations in operational difficulty and outcomes across stages. Therefore, for reservoirs with strong heterogeneity, stage-specific designs must account for localized features to enhance success rates and production gains.
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http://dx.doi.org/10.1038/s41598-025-12773-2 | DOI Listing |
Sci Rep
July 2025
Henan Mechanical and Electrical Vocational College, Zhengzhou, 451192, Henan, China.
To address the issue of low production output, additional stimulation measures are always adopted.This study analyzes the complex characteristics of the Chang-7 shale gas reservoir in the central Tianhuan Syncline, Ordos Basin. Facing challenges from reservoir heterogeneity, we implemented a multi-stage fracturing pilot in the first horizontal well (DPX) of the Chang-7 reservoir using drillable bridge plug technology and customized fracturing designs based on horizontal well multi-stage stimulation theory and multi-fracture interference mechanisms.
View Article and Find Full Text PDFBackground: Falls epidemiology in the Middle East and North Africa (MENA) remains underexplored despite being a major cause of morbidity and mortality. We synthesised the data on unintentional falls among older adults in MENA countries.
Methods: We conducted a systematic review, meta-analysis, and meta-regression, searching MEDLINE/PubMed, Web of Science, and Google Scholar up to 5 May 2024, without language or time restriction.
Sci Rep
March 2025
The 12th Geological Brigade of Sichuan, Yibin, 644002, Sichuan, China.
Landslides are one of the most common natural disasters worldwide. On September 27, 2020, a large-scale landslide occurred in the Tianzhulin area of Huangni Village, Wenjiang Town, Gao County, known as the Wachangwan Landslide. Through field investigations and UAV aerial photography, the causes and deformation processes of the Wachangwan landslide were thoroughly revealed.
View Article and Find Full Text PDFBMC Musculoskelet Disord
February 2025
Department of Orthopedics and Traumatology, Manisa Celal Bayar University Faculty of Medicine, Manisa, 45020, Turkey.
Background: Chronic permenant lateral patellar dislocation is a rare, complex condition that affects an adult's entire lower extremity and may cause functional impairment. This study aimed to identify single-stage surgery for functional recovery in patients and to assess the radiological and functional outcomes of our technique, particularly concerning patellofemoral osteoarthrosis, at mid-term follow-up.
Methods: The study retrospectively analyzed eight patients with eleven afflicted knees who had our novel surgical method, termed the all-in-one treatment, from 2011 to 2017.
Adv Mater
March 2025
National Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu, Sichuan, 610065, China.
Osteoporosis, characterized by low bone mass and high fracture risk, challenges orthopedic implant design. Conventional 3D-printed Ti6Al4V scaffolds are mechanically robust but suffer from poor bone regeneration in osteoporotic patients due to stress shielding and cellular senescence. In this study, a functionalized 3D-printed Ti6Al4V "Cell Climbing Frame" is developed, aiming to adapt to the mechanical microenvironment of osteoporosis, effectively recruit and support the adhesion and growth of autologous bone marrow mesenchymal stem cells (BMSCs), while rejuvenating senescent cells for improved bone regeneration.
View Article and Find Full Text PDF