257 results match your criteria: "Institute for Systems and Computer Engineering[Affiliation]"

The detection of arterial pulsating signals at the skin periphery with Photoplethysmography (PPG) are easily distorted by motion artifacts. This work explores the alternatives to the aid of PPG reconstruction with movement sensors (accelerometer and/or gyroscope) which to date have demonstrated the best pulsating signal reconstruction.A generative adversarial network with fully connected layers is proposed for the reconstruction of distorted PPG signals.

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AI-based models to predict decompensation on traumatic brain injury patients.

Comput Biol Med

March 2025

INESC TEC - Institute for Systems and Computer Engineering, Technology and Science, Porto, Portugal; FCTUC - Faculty of Sciences and Technology of the University of Coimbra, Coimbra, Portugal. Electronic address:

Traumatic Brain Injury (TBI) is a form of brain injury caused by external forces, resulting in temporary or permanent impairment of brain function. Despite advancements in healthcare, TBI mortality rates can reach 30%-40% in severe cases. This study aims to assist clinical decision-making and enhance patient care for TBI-related complications by employing Artificial Intelligence (AI) methods and data-driven approaches to predict decompensation.

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Histology is a preclinical subject transversal in medical, dental, and veterinary curricula. Classical teaching approaches in histology are often undermined by lower motivation and engagement of students, which may be addressed by innovative learning environments. Herein, we developed a serious game approach and compared it with a classical teaching style.

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Objectives: The shape is commonly used to describe the objects. State-of-the-art algorithms in medical imaging are predominantly diverging from computer vision, where voxel grids, meshes, point clouds, and implicit surface models are used. This is seen from the growing popularity of ShapeNet (51,300 models) and Princeton ModelNet (127,915 models).

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An automatic system for pathology classification in chest X-ray scans needs more than predictive performance, since providing explanations is deemed essential for fostering end-user trust, improving decision-making, and regulatory compliance. CLARE-XR is a novel methodology that, when presented with an X-ray image, identifies the associated pathologies and provides explanations based on the presentation of similar cases. The diagnosis is achieved using a regression model that maps an image into a 2D latent space containing the reference coordinates of all findings.

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Canine hip dysplasia (CHD) screening relies on accurate positioning in the ventrodorsal hip extended (VDHE) view, as even mild pelvic rotation can affect CHD scoring and impact breeding decisions. This study aimed to assess the association between pelvic rotation and asymmetry in obturator foramina areas (AOFAs) and to develop a computer vision model for automated AOFA measurement. In the first part, 203 radiographs were analyzed to examine the relationship between pelvic rotation, assessed through asymmetry in iliac wing and obturator foramina widths (AOFWs), and AOFAs.

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: Cancer patients undergoing chemotherapy often face challenges that reduce their physical function and quality of life. Technological resources offer innovative solutions for physical rehabilitation, but the extent of their application in this context remains unclear. This scoping review aims to explore and map the various technological tools used to support physical rehabilitation in cancer patients during chemotherapy, focusing on their potential to improve outcomes and enhance patient care.

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Although the classification of chest radiographs has long been an extensively researched topic, interest increased significantly with the onset of the COVID-19 pandemic. Existing results are promising; however, the radiological similarities between COVID-19 and other types of respiratory diseases limit the success of conventional image classification approaches that focus on single instances. This study proposes a novel perspective that conceptualizes COVID-19 pneumonia as a deviation from a normative distribution of typical pneumonia patterns.

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Aligning priorities: A Comparative analysis of scientific and policy perspectives on municipal solid waste management.

Waste Manag

February 2025

Department of Industrial Engineering and Management, Faculty of Engineering of University of Porto, R. Roberto Frias, 4200-465, Porto, Portugal; INESC TEC - Institute for Systems and Computer Engineering, Technology and Science, R. Roberto Frias, 4200-465, Porto, Portugal.

Article Synopsis
  • Municipal solid waste (MSW) management presents significant economic, environmental, and social challenges that need comprehensive research and effective policies for sustainable solutions.
  • * This study uses two Latent Dirichlet Allocation (LDA) models to analyze themes in scientific literature and EU-funded projects, finding that both realms show alignment in addressing key MSW issues.
  • * The analysis reveals a need for more research on specific topics like leaching and heavy metal extraction, while suggesting that future EU research should also prioritize waste prevention over just management.*
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: Obstructive sleep apnea (OSA) classification relies on polysomnography (PSG) results. Current guidelines recommend the development of clinical prediction algorithms in screening prior to PSG. A recent intuitive and user-friendly tool (OSABayes), based on a Bayesian network model using six clinical variables, has been proposed to quantify the probability of OSA.

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Background And Objectives: Early detection of cognitive impairment is crucial for timely clinical interventions aimed at delaying progression to dementia. However, existing screening tools are not ideal for wide population screening. This study explores the potential of combining machine learning, specifically, one-class classification, with simpler and quicker motor-cognitive tasks to improve the early detection of cognitive impairment.

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APAtizer: a tool for alternative polyadenylation analysis of RNA-Seq data.

Bioinformatics

November 2024

Gene Regulation Group, i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, 4200-135, Portugal.

Summary: APAtizer is a tool designed to analyze alternative polyadenylation events on RNA-sequencing data. The tool handles different file formats, including BAM, htseq, and DaPars bedGraph files. It provides a user-friendly interface that allows users to generate informative visualizations, including Volcano plots, heatmaps, and gene lists.

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This paper presents a new type of phase-shifted Fiber Bragg Grating (FBG): the sliced-FBG (SFBG). The fabrication process involves cutting a standard FBG inside its grating region. As a result, the last grating pitch is shorter than the others.

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Computer simulations, which are performed at a single wavelength at a time, have been traditionally used to estimate the optical properties of tissues. The results of these simulations need to be interpolated. For a broadband estimation of tissue optical properties, the use of computer simulations becomes time consuming and computer demanding.

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Article Synopsis
  • Obstructive sleep apnea (OSA) is a diverse sleep disorder, and researchers have previously analyzed its different phenotypes using various clustering methods.
  • This study tested four clustering techniques (Agglomerative Hierarchical Clustering, K-means, Fuzzy C-means, and Gaussian Mixture Model) on 865 patients to see how method selection influences the classification of OSA clusters and their physiological differences.
  • Results showed that two clusters were consistently distinct across all methods, while three had overlapping features; K-means performed best overall, and Fuzzy C-means excelled in managing overlapping clusters, underscoring the significance of clustering method choice in OSA phenotyping.
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Article Synopsis
  • - Pollination is essential for crops like kiwifruit, which face challenges due to their dioecious nature, with separate male and female flowers, and a lack of nectar to attract pollinators.
  • - The study highlights two significant research gaps: methods for detecting the gender of Actinidia flowers and the limited use of deep learning approaches in this area.
  • - Four pretrained models were tested for flower detection, with DETR performing the best in terms of precision and recall, suggesting that deep learning can advance robotic pollination systems for these plants.
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A survey on cell nuclei instance segmentation and classification: Leveraging context and attention.

Med Image Anal

January 2025

INESC TEC - Institute for Systems and Computer Engineering, Technology and Science, R. Dr. Roberto Frias, Porto, 4200-465, Portugal; University of Porto - Faculty of Engineering, R. Dr. Roberto Frias, Porto, 4200-465, Portugal.

Nuclear-derived morphological features and biomarkers provide relevant insights regarding the tumour microenvironment, while also allowing diagnosis and prognosis in specific cancer types. However, manually annotating nuclei from the gigapixel Haematoxylin and Eosin (H&E)-stained Whole Slide Images (WSIs) is a laborious and costly task, meaning automated algorithms for cell nuclei instance segmentation and classification could alleviate the workload of pathologists and clinical researchers and at the same time facilitate the automatic extraction of clinically interpretable features for artificial intelligence (AI) tools. But due to high intra- and inter-class variability of nuclei morphological and chromatic features, as well as H&E-stains susceptibility to artefacts, state-of-the-art algorithms cannot correctly detect and classify instances with the necessary performance.

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Article Synopsis
  • The past two decades have seen a surge in interest and investment in AI, fueled by increased data, better computing power, and advanced modeling techniques.* -
  • Ophthalmology is one field utilizing AI to enhance telemedicine and imaging, but there are challenges to address before widespread implementation.* -
  • The article outlines a seven-step AI lifecycle, highlighting risks and proposing strategies for each phase, from data collection to post-deployment evaluation.*
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Article Synopsis
  • The study investigates how space missions impact oral health, highlighting challenges like increased periodontitis and tooth sensitivity experienced by astronauts.
  • It involved 16 participants, including astronaut candidates, who compared their oral hygiene practices on Earth versus during simulated space missions, emphasizing difficulties like time constraints and limited access to dental materials.
  • Results indicate that while most participants maintained a "good" oral hygiene routine, they faced more symptoms on Earth than during missions, suggesting that more research is needed to better understand oral health in extreme environments.
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Are Aptamer-Based Biosensors the Future of the Detection of the Human Gut Microbiome?-A Systematic Review and Meta-Analysis.

Biosensors (Basel)

September 2024

INESC TEC-Institute for Systems and Computer Engineering, Technology and Science, University of Porto, 4169-007 Porto, Portugal.

The gut microbiome is shaped early in life by dietary and lifestyle factors. Specific compounds in the gut affect the growth of different bacterial species and the production of beneficial or harmful byproducts. Dysbiosis of the gut microbiome has been linked to various diseases resulting from the presence of harmful bacteria and their byproducts.

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Diabetic foot is a serious complication that poses significant risks for diabetic patients. The resulting reduction in protective sensitivity in the plantar region requires early detection to prevent ulceration and ultimately amputation. The primary method employed for evaluating this sensitivity loss is the 10 gf Semmes-Weinstein monofilament test, commonly used as a first-line procedure.

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Inspecting and maintaining power lines is essential for ensuring the safety, reliability, and efficiency of electrical infrastructure. This process involves regular assessment to identify hazards such as damaged wires, corrosion, or vegetation encroachment, followed by timely maintenance to prevent accidents and power outages. By conducting routine inspections and maintenance, utilities can comply with regulations, enhance operational efficiency, and extend the lifespan of power lines and equipment.

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Healthcare AI faces an ethical dilemma between selective and equitable deployment, exacerbated by flawed performance metrics. These metrics inadequately capture real-world complexities and biases, leading to premature assertions of effectiveness. Improved evaluation practices, including continuous monitoring and silent evaluation periods, are crucial.

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Plasmonic nanoparticle sensors: current progress, challenges, and future prospects.

Nanoscale Horiz

November 2024

CINBIO, Department of Physical Chemistry, Universidade de Vigo, 36310 Vigo, Spain.

Plasmonic nanoparticles (NPs) have played a significant role in the evolution of modern nanoscience and nanotechnology in terms of colloidal synthesis, general understanding of nanocrystal growth mechanisms, and their impact in a wide range of applications. They exhibit strong visible colors due to localized surface plasmon resonance (LSPR) that depends on their size, shape, composition, and the surrounding dielectric environment. Under resonant excitation, the LSPR of plasmonic NPs leads to a strong field enhancement near their surfaces and thus enhances various light-matter interactions.

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A Clinician's Guide to Understanding Bias in Critical Clinical Prediction Models.

Crit Care Clin

October 2024

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Duke University, Durham, NC, USA; Department of Biostatistics and Bioinformatics, Duke University, Division of Translational Biomedical Informatics, Durham, NC, USA. Electronic address:

This narrative review focuses on the role of clinical prediction models in supporting informed decision-making in critical care, emphasizing their 2 forms: traditional scores and artificial intelligence (AI)-based models. Acknowledging the potential for both types to embed biases, the authors underscore the importance of critical appraisal to increase our trust in models. The authors outline recommendations and critical care examples to manage risk of bias in AI models.

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