Question-centered prompt engineering for nursing simulation debriefing: Model development and validation.

Aim: This study aims to develop and validate an instructional debriefing model that combines question-centered learning methodology with AI prompt engineering techniques for nursing simulations.

Background: Integrating artificial intelligence (AI)-based prompt engineering into nursing simulation offers structured strategies to enhance clinical reasoning. However, current debriefing models insufficiently incorporate AI methodologies such as question-centered learning and prompt engineering, indicating a lack of theoretical and procedural frameworks METHODS: The model was developed using a four-phase approach: (1) literature review, (2) instructor interviews, (3) expert validation and (4) external evaluation of effectiveness.

Sulfiredoxin stimulates luteinization in vitro by promoting progesterone production in rats.

In Brief: Sulfiredoxin (Srxn1) is essential for corpus luteum formation during ovulation. Inhibition of Srxn1 with J14 suppressed LH-stimulated progesterone production, key gene expressions (Cyp11a1, StAR), and markers of luteinization. This highlights Srxn1's role in promoting LH-induced luteinization through the ERK, C/EBPβ, and Cyp11a1 pathways.

Long-term clinical outcomes according to first responsive dose of acetylcholine in patients with coronary artery spasm.

Background: Coronary artery spasm (CAS) has become a focus of recent prognostic studies. However, research evaluating prognosis based on the initial dose of acetylcholine (ACH) at which patients first respond is lacking. This study aims to investigate long-term clinical outcomes according to the first responsive dose of ACH in patients with CAS.

Effect of spp. Supplementation for Improving Muscle Health: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis aimed to assess the quantitative effects of probiotic supplementation on improving muscle health, including muscle mass, lean mass, and hand grip strength, compared with a placebo. Databases were searched from PubMed, Embase, and Cochrane Library through January 2024. Researchers independently reviewed the studies using the quality assessment tool.

Effects of Gratitude Journaling on Patients with Breast Cancer: A Randomized Controlled Trial.

Gratitude journaling is a simple and effective way to improve emotional well-being. However, its impact on people with breast cancer in South Korea has not been clearly understood. This study explored how writing a gratitude journal can help patients with breast cancer feel more grateful, resilient, and satisfied with life.

Protein Microplastic Coronation Complexes Trigger Proteome Changes in Brain-Derived Neuronal and Glial Cells.

The extensive distribution of microplastics (MPs) in the environment and their food chain contamination urgently necessitates a deeper understanding of their molecular-level impact on physiological responses. This study employed a mass spectrometry-based proteomics approach to investigate the potential risks, mechanisms of associated cellular processes, and biological reactions to preformed protein-MPs coronation and intact MPs using brain-derived neuronal and glial cells. Our findings indicate that MPs can adsorb proteins and form a heterogeneous corona layer when interacting with biological fluids such as serum.

The impact of IRT and IDT on metaverse adoption in tourism: The moderating role of personal innovativeness among China's generation Z.

This study examines the Metaverse-a virtual world that merges entertainment, work, and social interactions-in terms of leisure tourism, using the frameworks of innovation resistance and diffusion theories. It explores the factors that drive and hinder Chinese Gen Z tourists' resistance to Metaverse technology, including the moderating role of personal innovativeness. An analysis of data from 400 Chinese Gen Z tourists revealed that, in addition to risk barriers, factors such as value, usage, image, and traditional barriers significantly impact innovation resistance.

Future direction of digital textbooks in undergraduate nursing education: A scoping review.

Digital natives have emerged, and nursing educator must develop digital textbook(DT)s the meet their information processing methods. But literature reviews on DTs remain insufficient. This scoping review aims to guide nursing educators on the future direction of DTs in undergraduate nursing education.

Enhanced antibacterial and anti-inflammatory properties of Hwangryeonhaedok-tang fermented with Kimchi-derived Lactiplantibacillus plantarum WiKim0111 for potential acne treatment.

Recent years have seen an increase in the incidence of acne in adults and teenagers resulting in active research in acne treatment. In the present study, we aimed to improve the anti-acne effects of Hwangryeonhaedok-tang (HHT) through fermentation using a kimchi-derived lactic acid bacterium. Lactiplantibacillus plantarum WiKim0111 (Lpb.

Impact of diabetes and ejection fraction on non-ST-Segment elevation myocardial infarction outcomes.

Given the limited published data, we examined three-year outcomes in patients with and without diabetes mellitus (DM) in non-ST-segment elevation myocardial infarction (NSTEMI), according to left ventricular ejection fraction (LVEF). A total of 4594 patients were classified into DM (n = 1608) and non-DM (n = 2986) groups. They were further classified into heart failure with reduced EF (HFrEF, LVEF ≤ 40%), HF with mildly reduced EF (HFmrEF, LVEF 41-49%), and HF with preserved EF (HFpEF, LVEF ≥ 50%) subgroups.

Association Between Vasomotor Response to Ergonovine Provocation Test and Non-Severe Coronary Artery Stenosis.

Background: Coronary artery spasm (CAS) causes vasospastic angina in patients without significant coronary artery stenosis. However, there has been limited investigation regarding the CAS patterns within this population. This study aims to evaluate the incidence and patterns of CAS in patients with non-severe coronary artery stenosis using intracoronary ergonovine (ERG) provocation test.

Disparities in Heart Transplantation Allocation and Outcomes by Blood Type in Korea (2010-2022).

Background And Objectives: This study aimed to elucidate the influence of recipient blood type on heart transplant allocation dynamics in Korea, focusing on donor matching, wait times, and post-transplant survival from 2010 to 2022.

Methods: In this retrospective cohort study, we examined 1,745 heart transplant recipients classified by blood types: A (n=631), B (n=488), AB (n=256), and O (n=370). Parameters studied encompassed donor and recipient ages, donor blood type compatibility, organ type, emergency status, waiting periods, and survival rates up to one year post-transplant.

The impact of intimate partner violence on facial emotion recognition among Korean baby boomers.

Intimate partner violence (IPV) can have lasting psychological and cognitive effects, potentially impairing facial emotion recognition (FER). This study examines the accuracy of FER among IPV survivors compared to individuals without IPV experience within the Korean baby boomer generation, aged 60-69, exploring the relationship between IPV, post-traumatic stress disorder (PTSD) symptoms, and FER abilities. To assess whether IPV impacts FER accuracy and intensity and to investigate whether symptoms of PTSD moderate this relationship.

Comparative Evaluation of Pre-Test Probability Models for Coronary Artery Disease with Assessment of a New Machine Learning-Based Model.

Purpose: This study aimed to validate pivotal pre-test probability (PTP)-coronary artery disease (CAD) models (CAD consortium model and IJC-CAD model).

Materials And Methods: Traditional PTP models-CAD consortium models: two traditional PTP models were used under the CAD consortium framework, namely CAD1 and CAD2. Machine learning (ML)-based PTP models: two ML-based PTP models were derived from CAD1 and CAD2, and used to enhance predictive capabilities [ML-CAD2 and ML-IJC (IJC-CAD)].

Should teaching strategies emphasize emotion or competence? Enhancing audience acceptance of children with autism through online music performances - evidence from China.

This study investigates the experiences and perceptions of audiences watching online music performances by children with autism, focusing on how the emotions and competence displayed by the children during the performances affect the audience's sense of immersion and acceptance. We conducted an online survey with 949 respondents, t-tests was used to compare the differences before and after the respondents watching the performance, and structural equation modeling was used to analyzed the path relationships among variables. The results showed that audience acceptance was significantly higher after watching the music performances (t = -6.

Influence of Critical Thinking Disposition, Clinical Reasoning Competence, and Nursing Practice Environment on Medication Safety Competence of Hospital Nurses.

Objectives: This study examined the impact of nurses' critical thinking disposition, clinical reasoning competency, and nursing practice environment on their medication safety competency.

Methods: A cross-sectional design was employed, involving a convenience sample of 210 nurses from four tertiary general hospitals and two general hospitals. Data were collected in September 2023 utilizing structured online self-report questionnaires and analyzed utilizing descriptive statistics, independent -tests, one-way analysis of variance, Pearson's correlation coefficients, and stepwise multiple regression with SPSS/WIN 28.

Validity and Reliability of the Korean Version of the Florida Patient Acceptance Survey.

Aim: To validate the Korean version of the Florida Patient Acceptance Survey (K-FPAS) and assess its reliability in evaluating the acceptance of implantable cardioverter defibrillators (ICDs) among Korean patients.

Design: A methodological research study was conducted to develop and validate the K-FPAS as a valuable tool for assessing ICD acceptance and its related factors in the Korean patient population.

Methods: A total of 243 participants, aged 18 years and older, who had received ICDs within the past year and were regularly monitored by cardiac specialists, were included in the study.

How to improve users' purchase intention of agricultural products through live streaming systems?

With the development and improvement of technology, live streaming systems have emerged in people's daily lives, providing new channels for agricultural product sales. This study aims to understand how to scientifically design live streaming systems for agricultural product sales based on user perceptions and preferences. We conducted an online survey, and Study 1 obtained 569 valid samples.

PRPF4 Knockdown Suppresses Glioblastoma Progression the p38 MAPK and ERK Signaling Pathways.

Background/aim: Pre-mRNA processing factor 4 (PRPF4), a core protein of U4/U6 small nuclear ribonucleoproteins (snRNPs), is crucial for maintaining their structure by interacting with PRPF3 and Cyclophilin H. Beyond its role in splicing, PRPF4 has been implicated in cell survival, apoptosis, and oncogenesis. Although PRPF4 mutations have been associated with retinitis pigmentosa, its role in glioblastoma (GBM) remains unclear.

A study on how to improve students' continuance intention in landscape architecture conservation course within a virtual learning environment based on SVVR.

With the rapid pace of global urbanization, preserving natural landscapes has become increasingly critical. However, urbanization presents significant environmental risks worsened by decreased ecological consciousness. This has led to a pressing demand for education in landscape conservation.

Deficits in facial emotion recognition and cognitive function among baby boomers.

Facial emotion recognition (FER), a key component of social cognition, plays a critical role in social interactions. In the aging process, FER among older adults holds significant potential as a tool for diagnosing cognitive function or enhancing interpersonal relationships. However, research in this area remains limited.

Attention Score-Based Multi-Vision Transformer Technique for Plant Disease Classification.

This study proposes an advanced plant disease classification framework leveraging the Attention Score-Based Multi-Vision Transformer (Multi-ViT) model. The framework introduces a novel attention mechanism to dynamically prioritize relevant features from multiple leaf images, overcoming the limitations of single-leaf-based diagnoses. Building on the Vision Transformer (ViT) architecture, the Multi-ViT model aggregates diverse feature representations by combining outputs from multiple ViTs, each capturing unique visual patterns.

How the nursing work environment moderates the relationship between clinical judgment and person-centered care among intensive care unit nurses.

Background: Person-centered care focuses on individualized care that respects patients' values, preferences, and autonomy. To enhance the quality of critical care nursing, institutions need to identify the factors influencing ICU nurses' ability to provide person-centered care. This study explored the relationship between clinical judgment ability and person-centered care among intensive care unit (ICU) nurses, emphasizing how the ICU nursing work environment moderates this relation.

Denatonium inhibits RANKL-induced osteoclast differentiation and rescues the osteoporotic phenotype by blocking p65 signaling pathway.

Background: Bone remodeling is a critical process that maintains skeletal integrity, orchestrated by the balanced activities of osteoclasts, which resorb bone, and osteoblasts, which form bone. Osteoclastogenesis, the formation of osteoclasts, is primarily driven by NFATc1, a process activated through c-Fos and NF-κB signaling pathways in response to receptor activator of nuclear factor κB ligand (RANKL). Dysregulation of RANKL signaling is a key contributor to pathological bone loss, as seen in conditions such as osteoporosis.