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Traffic accidents pose a significant threat to human life and property, and with the increasing presence of connected and autonomous vehicles (CAVs), effective risk assessment has become more critical. Current safety metrics, often limited to longitudinal or lateral assessments, fail to address omnidirectional risks or account for the uncertainties associated with vehicle intentions. This paper introduces a new omnidirectional safety metric, Interactive Risk (IR), which combines the concept of the driving risk field with multimodal trajectory prediction. IR captures the uncertainty of vehicle intentions, quantifies the probability and severity of potential accidents, and provides a comprehensive measure of traffic risk. Through case studies of typical collision scenarios and experiments with the simulation and real world dataset, we demonstrate that IR accurately reflects the risk levels faced by CAVs, detects collision risks earlier, and aligns more closely with human intuition compared to baseline safety metrics. Furthermore, we propose four key applications of IR, including traffic risk monitoring, ego-vehicle risk warning, driving decision-making performance evaluation, and motion and trajectory planning. The results highlight the potential of IR to enhance safety assessment in dynamic traffic environments and provide valuable insights for future research and application in autonomous vehicle systems.
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http://dx.doi.org/10.1016/j.aap.2025.108228 | DOI Listing |
Arterioscler Thromb Vasc Biol
September 2025
Institute of Cardiovascular Diseases and Department of Cardiology, Ultrasound in Cardiac Electrophysiology and Biomechanics Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu (K.L., H.M., W.J
Background: The estimated glucose disposal rate (eGDR) is a validated surrogate marker of insulin resistance. However, its association with stroke and dementia in nondiabetic populations remains insufficiently investigated.
Methods: This prospective cohort study included nondiabetic participants from the UK Biobank.
Hypertension
September 2025
Department of Hypertension, Center for Epidemiological Studies and Clinical Trials, the Shanghai Institute of Hypertension, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, China (J.W.).
Background: The association between season of screening blood pressure (BP) measurement and adverse outcomes has not been examined among populations without prior physician-diagnosed hypertension. We aimed to investigate the association between the season of screening clinic BP measurement and the risk of all-cause mortality.
Methods: This was a prospective cohort study, and data were analyzed from an ongoing community hypertension screening program in Shanghai between 2018 and 2024.
Circ Genom Precis Med
September 2025
Department of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, China (J.Z., S.R., L.C., M.C., F.T., B.A., Y.Y., H.L.).
Background: Previous studies have suggested that the associations between ambient air pollution and atherosclerotic cardiovascular diseases (ASCVD) differ by genotype. A genome-wide approach provides a more comprehensive understanding of this relationship on a genomic scale.
Methods: Using data from ≈300 000 UK Biobank participants, we conducted a genome-wide interaction analysis on 10 745 802 variants.
J Diabetes
September 2025
Division of Nephrology, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
Aims: Diabetes is a global public health crisis, especially when it is accompanied by microvascular complications such as diabetic kidney disease (DKD). The purpose of this study was to explore the relationship between the combined lifestyle factors of diabetes patients and their joint effects with genetic risk and the risk of DKD.
Materials And Methods: We included individuals diagnosed with diabetes at baseline from UK Biobank.
BMC Med Inform Decis Mak
September 2025
Emergency Department, Helios Spital, Überlingen, Germany.
Background: The increasing amount of data routinely collected on ICUs poses a challenge for clinicians which is aggravated with data-heavy therapies like Continuous Kidney Replacement Therapy (CKRT). We developed the CKRT Supporting Software Prototype (CKRT-SSP), a clinical decision support system for use before, during and after CKRT. The aim of this user experience (UX) study was to prospectively evaluate CKRT-SSP in terms of usability, user experience, and workload in a simulated ICU setting.
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