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Objective: To assess the impact of gestational diabetes(GDM) detection thresholds on infant growth, nutrition, and neurodevelopment at 12-18 months.
Design: Prospective cohort study within the GEMS trial(ACTRN12615000290594), which randomized pregnant women to detection of GDM using lower or higher glycemic criteria. The main outcomes were overweight/rapid weight gain; food approach appetitive score; energy intake; cognitive z-score.
Result: Compared to control infants, those exposed to GDM detected and treated by higher criteria or by lower but not higher criteria that was untreated, were less likely to have increased overweight/rapid weight gain, possibly with lower energy intake. There were no important differences in appetite and cognition. Infants exposed to GDM by lower but not higher criteria that was treated were similar to controls.
Conclusion: Exposure to treated GDM or untreated GDM detected by lower but not higher criteria, was not associated with increased infant risk factors for obesity or adverse cognitive outcomes.
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http://dx.doi.org/10.1038/s41372-025-02406-x | DOI Listing |
Mol Nutr Food Res
September 2025
University of Southampton, Southampton, Hampshire, UK.
Potatoes are a global staple, yet their nutritional potential is underutilized. This study evaluates the biochemical and nutritional composition of Solanum okadae (S. okadae), a wild diploid potato species, compared to the cultivated S.
View Article and Find Full Text PDFBr J Cancer
September 2025
School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
Background: Studies examining the association of chronic kidney disease (CKD) with cancer risk have demonstrated conflicting results.
Methods: This was an individual participant data meta-analysis including 54 international cohorts contributing to the CKD Prognosis Consortium. Included cohorts had data on albuminuria [urine albumin-to-creatinine ratio (ACR)], estimated glomerular filtration rate (eGFR), overall and site-specific cancer incidence, and established risk factors for cancer.
Environ Sci Pollut Res Int
September 2025
Civil and Environmental Engineering Department, King Fahd University of Petroleum & Minerals, 31261, Dhahran, Saudi Arabia.
Concrete production significantly contributes to CO emissions and depletion of natural resources, leading to substantial environmental concerns. The integration of polymers into concrete has emerged as a promising innovative solution aimed at overcoming inherent limitations of traditional concrete, including brittleness, susceptibility to tracking, environmental degradation, and substantial ecological impacts. This systematic review thoroughly investigates the properties, sustainability implications, and practical challenges associated with polymer-based concrete (PBC), particularly focusing on polymer concrete composites (PCC) and polymer-modified concrete (PMC) detailing their composition, mechanical behavior, and durability.
View Article and Find Full Text PDFSurgeon
September 2025
Department of Vascular and Endovascular Surgery, Waterford University Hospital, Waterford, Ireland; University College Cork, Ireland; Department of Vascular and Endovascular Surgery, Faculty of Medicine, Mansoura University, Mansoura, Egypt. Electronic address:
Background: The management of diabetic foot infections (DFIs) is a complex multidisciplinary process and often necessitates surgical interventions. Unfortunately, amputations such as single or multiple toes amputations (MTA) or full transmetatarsal amputation (TMA) are often the unavoidable solution. This study aimed to compare the clinical outcomes of TMA versus MTA in managing non-ischemic diabetic foot infections.
View Article and Find Full Text PDFJ Am Med Dir Assoc
September 2025
Irish National Audit of Stroke Care, National Office of Clinical Audit, Dublin, Ireland; St Vincent's University Hospital, Dublin, Ireland.
Objectives: Internationally about 3% of people ≥65 years live in long-term care (LTC) settings. Older people living in nursing homes are more likely to be admitted to hospital. We examined the characteristics and outcomes of stroke patients admitted from LTC nationally and how this changed over the COVID-19 pandemic.
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