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Objective: Prevalence of hospital-acquired pressure injury (PI), as a critical measurement of medical care quality, has shown an upward trend. The aim of this study was to determine the predictive indicators of potential PIs and ensure that the predictive indicators can automatically be mined from electronic medical record systems.
Methods: The methods include 2 parts. One is the modified Delphi for indicator development, including clinical health care provider interviews, literature review, research group meetings, and Delphi survey. The other is feature selection, including extracting indicators from the health care information system (HIS) by structured query language and selecting indicators using the Random Forest technique.
Results: A predictive indicator system (with feature extraction rules for each indicator) consisting of 3 categories and 14 indicators was constructed. The experts' consensus was reached on all indicators (mean=4.28±0.65 to 4.94±0.23; coefficient of variation=4.63% to 17.20%; agreement rate=83.30% to 100.00%). The agreement between manual extraction and the computer's automatic extraction was good, with a Cohen κ score of 0.64 to 1.00. The accuracy of the good parsimonious prediction model was 95.26%.
Conclusions: This predictive indicator system is prepared for automatic PI prediction in the HIS. Many revisions should be conducted in further studies and practices in a real-life medical environment.
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http://dx.doi.org/10.1097/ASW.0000000000000350 | DOI Listing |
J Magn Reson Imaging
September 2025
Department of Neurology, Dell Medical School, University of Texas at Austin, Austin, Texas, USA.
Background: Cerebrovascular reactivity reflects changes in cerebral blood flow in response to an acute stimulus and is reflective of the brain's ability to match blood flow to demand. Functional MRI with a breath-hold task can be used to elicit this vasoactive response, but data validity hinges on subject compliance. Determining breath-hold compliance often requires external monitoring equipment.
View Article and Find Full Text PDFZhong Nan Da Xue Xue Bao Yi Xue Ban
May 2025
Department of Rheumatology and Immunology, Xiangya Hospital, Central South University, Changsha 410008.
Objectives: Patients with connective tissue diseases (CTD) have a high incidence of cardiac involvement, which often presents insidiously and can progress rapidly, making it one of the leading causes of death. Multiparametric cardiovascular magnetic resonance (CMR) provides a comprehensive quantitative evaluation of myocardial injury and is emerging as a valuable tool for detecting cardiac involvement in CTD. This study aims to investigate the correlations between CMR features and serological biomarkers in CTD patients, assess their potential clinical value, and further explore the impact of pre-CMR immunotherapy intensity on CMR-specific parameters, thereby evaluating the role of CMR in the early diagnosis of CTD-related cardiac involvement.
View Article and Find Full Text PDFDalton Trans
September 2025
Departamento de Fisica Aplicada-ICMUV, MALTA Consolider Team, Universitat de Valencia, Av. Dr. Moliner 50, 46100 Burjassot (Valencia), Spain.
The impact of external pressure on the characteristics of SrTeO has been thoroughly examined using density-functional theory calculations up to 100 GPa. It has been predicted that SrTeO undergoes three phase transitions in the pressure range covered by this study. A first transition occurs at 2.
View Article and Find Full Text PDFChem Biol Drug Des
September 2025
Laboratory of Biochemistry and Animal Toxins, Institute of Biotechnology, Federal University of Uberlandia, Uberlandia, MG, Brazil.
Leishmaniasis, a disease caused by Leishmania parasites, poses a significant health threat globally, particularly in Latin America and Brazil. Leishmania amazonensis is an important species because it is associated with both cutaneous leishmaniasis and an atypical visceral form. Current treatments are hindered by toxicity, resistance, and high cost, driving the need for new therapeutic targets and drugs.
View Article and Find Full Text PDFDiabetes Metab J
September 2025
Department of Epidemiology and Health Promotion, Institute for Health Promotion, Graduate School of Public Health, Yonsei University, Seoul, Korea.
Background: This study aimed to investigate the association between adiponectin levels and the incidence of metabolic dysfunction- associated steatotic liver disease (MASLD) and nonalcoholic fatty liver disease (NAFLD), and to explore the predictive value of adiponectin in the onset of these conditions.
Methods: A 17-year follow-up of 35,026 individuals from the Korean Cancer Prevention Study-II biobank cohort (2004-2021) was conducted. Adiponectin levels were categorized into quintiles.