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http://dx.doi.org/10.1093/plphys/kiaf389 | DOI Listing |
Microb Genom
September 2025
School of Animal and Veterinary Sciences, The University of Adelaide, Roseworthy, South Australia 5371, Australia.
causes otitis media and severe diseases including pneumonia, meningitis and bacteraemia. The rise of antimicrobial resistance (AMR) in , facilitated by mobile genetic elements (MGEs), complicates infection treatment. While pneumococcal conjugate vaccine (PCV) deployment has reduced disease burden, non-vaccine serotypes (NVTs) have increased and now cause invasive disease.
View Article and Find Full Text PDFCurr Biol
July 2025
Key Laboratory of Marine Ecology and Environmental Sciences, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China; Laboratory for Marine Ecology and Environmental Science, Qingdao Marine Science and Technology Center, Qingdao 266237, China. Electronic address: jinxianliu@gmail
Determination of evolutionary mechanisms underlying innovative traits is crucial for understanding the vast diversity of species and phenotypes. Given their respiratory physiologies, fishes are compelling subjects for evolutionary analysis of the hemoprotein-based oxygen-transport systems. Asian noodlefishes (Osmeriformes: Salangidae) and Antarctic icefishes (Notothenioidei: Channichthyidae) are examples of fish clades that generally do not express myoglobin or hemoglobin.
View Article and Find Full Text PDFSci Immunol
September 2025
Laboratory of Epigenetics and Immunology, West China Institute of Women and Children's Health, NHC Key Laboratory of Chronobiology, State Key Laboratory of Biotherapy, West China Second University Hospital, Sichuan University, Chengdu, China.
Naïve T cells are maintained in a homeostatic state to preserve a stable T cell pool with diverse T cell receptor (TCR) repertoires, ensuring preparedness for priming. However, the underlying mechanisms controlling naïve T cell homeostasis and priming remain unclear. Leveraging a machine learning-based functional genetic screen, we identified () as the top factor responsible for naïve T cell homeostasis.
View Article and Find Full Text PDFPlant Physiol
September 2025
Shandong Agricultural University, Tai'an, Shandong, 271018, China.
Front Cell Infect Microbiol
August 2025
Chinese People's Liberation Army of China (PLA) Center for Disease Control and Prevention, Beijing, China.
Background: , which encodes a metallo-β-lactamase that can hydrolyze most β-lactam antibiotics, has become a serious public health concern in China. It is crucial to investigate the evolution, dissemination, and genetic dynamics of to develop potential strategies to control the proliferation of .
Methods: In this study, we collected 1021 -positive isolates, which features 67 new genomes from our laboratory and 954 genomes from NCBI.