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To develop and validate a Pediatric Pharmacological Readiness Assessment Scale for recurrent respiratory infections, focusing on medication adherence, caregiver pharmacological knowledge, and pharmacist-led interventions. An initial scale was constructed through literature review, expert consultation, and a pilot survey, guided by the Pharmaceutical Care Practice Model. A convenience sample of 156 primary caregivers of children hospitalized for recurrent respiratory infections was surveyed between April 2023 and April 2024. Item analysis and reliability and validity testing were conducted. The final scale includes 34 items across seven dimensions: child's condition, parental condition, pharmacological knowledge, medication attitudes, adherence behavior, coping ability, and anticipated support. The overall Cronbach's α was 0.934, with split-half reliability at 0.826. Dimensional Cronbach's α values ranged from 0.834 to 0.925, and split-half reliability from 0.819 to 0.957. Content validity indices (I-CVI: 0.835 - 1.000; S-CVI: 0.902) were high. Exploratory factor analysis identified seven factors explaining 73.617% of variance. The scale demonstrates good reliability and validity, accurately reflecting pharmacological readiness. It is a valuable tool for clinical pharmacists to enhance discharge preparedness, improve medication adherence, and reduce readmissions.
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http://dx.doi.org/10.36721/PJPS.2025.38.4.REG.14102.1 | DOI Listing |
J Infect Dev Ctries
August 2025
Department of Oral Radiology, College of Dentistry, Jouf University, Kingdom of Saudi Arabia.
Introduction: The coronavirus disease 2019 (COVID-19) pandemic highlighted the importance of public knowledge, vaccination, government preparedness, and a strong healthcare system in managing infectious diseases. Recently, monkeypox (mpox) cases have emerged globally. This study aimed to assess: (i) the public knowledge related to COVID-19 and its translation into preventive behavior, and (ii) the preparedness of the government and healthcare providers in addressing mpox.
View Article and Find Full Text PDFCell Mol Biol (Noisy-le-grand)
September 2025
Department of Public Health, College of Applied Medical Sciences, Qassim University, Buraydah, 51452 P.O. Box 6666, Saudi Arabia.
Foodborne illnesses pose a significant public health threat globally, particularly in Saudi Arabia, where the rapid growth of the food service sector has increased the risk of exposure to multidrug-resistant (MDR) bacteria. Traditional microbiological methods are often time-consuming and may lack precision, highlighting the need for faster and more accurate diagnostic alternatives. In this study, Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) was employed for the rapid and precise identification of bacterial contaminants in ready-to-eat (RTE) foods, alongside an assessment of their antibiotic resistance profiles.
View Article and Find Full Text PDFOrg Lett
September 2025
State Key Laboratory of Chemistry for NBC Hazards Protection, Beijing 102205, China.
Optically active α-aminophosphonic acids are unique analogues of α-amino acids, and numerous synthetic methods have been developed. Herein, we present a highly diastereoselective α-azidation approach to the CAMDOL-derived phosphonates, enabling ready access to 27 diverse α-azidophosphonates with defined chirality in up to 85% yield and more than 99:1 dr. Late-stage transformations through the Staudinger reaction or click reaction efficiently delivered the related pharmacological α-aminophosphonic acids or the unique α-triazolylphosphonate derivative, respectively.
View Article and Find Full Text PDFChronic Obstructive Pulmonary Disease (COPD) has a progressive pathology that affects well-being quality of life. This study aimed to profile well-being in COPD patients across disease classifications. A cross-sectional survey ( = 179, = 111 female) was conducted using online self-report measures including the COPD Assessment Test, Medical Research Council Dyspnoea Scale, Fatigue Assessment Scale, Pittsburgh Sleep Quality Index (PSQI), health-related quality of life (EQ-5D-5L), Self-Compassion Scale Short Form, confidence to try a new intervention ruler and readiness to try a new intervention ruler.
View Article and Find Full Text PDFMedicine (Baltimore)
August 2025
Department of Pharmacology, Faculty of Medicine, King Abdul-Aziz University, Rabigh, Saudi Arabia.
Despite the growing prevalence of off-label prescribing, there is limited research exploring pharmacists' actual knowledge and practices, particularly in the Saudi context. Existing literature mainly focuses on physicians, leaving a gap in understanding pharmacists' readiness to handle such prescriptions. This study aimed to assess the knowledge and practices of pharmacy staff in Saudi Arabia regarding off-label drug use and examined the impact of education, age, gender, and experience on these outcomes.
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