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Light-responsive intelligent micromachines hold great promise in soft robotics owing to their localized actuation and flexible remote control. Nevertheless, it remains challenging to realize light-driven micromechanical structures featuring low actuation thresholds, rapid responses, and complex deformation capabilities. Here, a single-material-based dual-3D (3D programmable design and 3D deformation) printing strategy based on two-photon polymerization direct laser writing (TPP-DLW) technology is proposed for fabricating light-responsive smart actuators. The polydopamine nanoparticles are doped into the hydrogel as a photothermal conversion functional material. By virtue of the dual-3D printing strategy, precise control over voxel distribution and density at the nanoscale can be achieved to provide asymmetric crosslinking networks. Employing this approach, we successfully developed micro-crab claws that imitate the swinging and closing motions of actual crab appendages and humanoid micromachines capable of multi-degree-of-freedom "dancing" movements. The proposed strategy offers broad application potential in diverse areas.
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http://dx.doi.org/10.1364/OL.569667 | DOI Listing |
Small
August 2025
School of Materials Science and Engineering, Tongji University, Shanghai, 201804, P. R. China.
As an outstanding flexible conductive material, eutectogels have received increasing attention due to their potential applications in fields such as flexible wearable electronics and wireless communications. However, the development of multifunctional eutectogels with stability in underwater environments is still very challenging due to the high sensitivity of most deep eutectic solvents (DES) to water. Herein, a hydrophobic eutectogel is fabricated by simple photopolymerization, the introduction of macromolecular cross-linking agents, fluorine-rich monomers and dynamic light-responsive functional ammonium molybdate tetrahydrate (Mo), as well as multiple dynamic interactions within the eutectogel, endowed it with excellent mechanical properties (160 kPa), long-term underwater repetitive adhesion (102.
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August 2025
Centre for Flexible Electronics, Department of Electronics and Communication Engineering, Koneru Lakshmaiah Education Foundation, Guntur, Andhra Pradesh, India.
The integration of triboelectric nanogenerators (TENGs) into soft robotic systems marks a significant advancement toward autonomous, self-powered, and environmentally responsive machines. TENGs offer lightweight, flexible structures capable of efficiently converting mechanical energy into electricity, supporting both on-board power generation and active sensing. This review provides a comprehensive overview of recent progress in TENG-powered soft robotics, emphasizing developments in actuation, sensing, locomotion, and intelligent interaction.
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August 2025
School of Life Sciences, Westlake University, Hangzhou, China.
Light-responsive proteins play an essential role in all domains of life by sensing and responding to environmental light signals. However, the de novo design of light-responsive proteins with precisely defined structures and reversible responsive behaviours is an unmet challenge. Here we describe a computational approach to design protein-protein interactions regulated by non-canonical amino acids, focusing on the light-responsive phenylalanine-4'-azobenzene (AzoF).
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August 2025
Institute of Polymer Optoelectronic Materials and Devices, Guangdong Basic Research Center of Excellence for Energy & Information Polymer Materials, State Key Laboratory of Luminescent Materials and Devices, School of Materials Science and Engineering, South China University of Technology, Guangzhou
A class of light-mediated mechanotherapeutic agents was developed on the basis of conjugated oligoelectrolytes (COEs), which mimic the topology of lipid membranes and intrinsically exhibit excellent biocompatibility. Low-dose white light irradiation (20 milliwatts per square centimeter for 10 minutes) substantially decreased the half-maximal inhibitory concentration of the optimized COE against A549 cancer cells from more than 256 to 0.6 micromolar.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
August 2025
Department of Chemistry and Biochemistry, Texas State University, San Marcos, Texas, 78666, USA.
Tetra-ortho-fluoroazobenzenes (TFAs) exhibit several unique properties, including a large separation in the n→π absorption bands, which allows for efficient photoisomerization using green light, and exceptional thermal stability of their metastable Z-isomer. These features make them attractive for light-responsive applications, but controlling the thermal Z-to-E isomerization has remained a challenge. In this work, we present a hybrid molecular system that couples a TFA subunit with a spiropyran photoswitch.
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