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Background: Triage is an essential part of Emergency Medicine, which may be assisted by AI models due to limited availability of medical staff. However, AI models for aiding triage have difficulty in identifying levels that are difficult or ambiguous for human clinicians to distinguish. This study aims to develop a more reliable triage model that improves the accuracy of classification, especially for cases with moderate acuity.
Methods: We developed a new triage model called KUTS, a foundational classification model for emergency triage, which leverages a knowledge prompt-tuning encoder and an uncertainty-based classifier. KUTS takes tabular data and chief complaints as input, and then assign different acuity levels to patients based on their condition acuity. We trained and tested the model on multiple real-world emergency department datasets.
Results: Here we show that on the most difficult level for human to distinguish (moderate acuity level), our KUTS substantially outperforms the previous shallow single-modal methods, deep single-modal methods and deep multi-modal methods on AUC score, by an average of 0.19, 0.35, and 0.13 (from 0.76, 0.60, 0.82 to 0.95), respectively. Besides, on all the triage levels, our KUTS also outperforms the previous shallow single-modal methods, deep single-modal methods and deep multi-modal methods on AUC score, by an average of 0.14, 0.20 and 0.06 (from 0.82, 0.76, 0.90 to 0.96), respectively.
Conclusions: KUTS provides a foundational framework and paradigm for the study of emergency triage, and facilitates the development of more efficient triage systems.
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http://dx.doi.org/10.1038/s43856-025-01052-w | DOI Listing |
JMIR Form Res
September 2025
Department of Critical Care Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangdong Provincial Geriatrics Institute, No. 106, Zhongshaner Rd, Guangzhou, 510080, China, 86 15920151904.
Background: Point-of-care ultrasonography has become a valuable tool for assessing diaphragmatic function in critically ill patients receiving invasive mechanical ventilation. However, conventional diaphragm ultrasound assessment remains highly operator-dependent and subjective. Previous research introduced automatic measurement of diaphragmatic excursion and velocity using 2D speckle-tracking technology.
View Article and Find Full Text PDFAdv Sci (Weinh)
September 2025
School of Artificial Intelligence, Jilin University, Changchun, 130012, China.
Single-cell multi-omics technologies are pivotal for deciphering the complexities of biological systems, with Cellular Indexing of Transcriptomes and Epitopes by Sequencing (CITE-seq) emerging as a particularly valuable approach. The dual-modality capability makes CITE-seq particularly advantageous for dissecting cellular heterogeneity and understanding the dynamic interplay between transcriptomic and proteomic landscapes. However, existing computational models for integrating these two modalities often struggle to capture the complex, non-linear interactions between RNA and antibody-derived tags (ADTs), and are computationally intensive.
View Article and Find Full Text PDFCancer Res Treat
September 2025
Department of Biostatistics, Harbin Medical University, Harbin, China.
Purpose: Locally advanced rectal cancer (LARC) exhibits significant heterogeneity in response to neoadjuvant chemotherapy (NAC), with poor responders facing delayed treatment and unnecessary toxicity. Although MRI provides spatial pathophysiological information and proteomics reveals molecular mechanisms, current single-modal approaches cannot integrate these complementary perspectives, resulting in limited predictive accuracy and biological insight.
Materials And Methods: This retrospective study developed a multimodal deep learning framework using a cohort of 274 LARC patients treated with NAC (2012-2021).
World J Gastroenterol
August 2025
Department of Gastroenterology, Qilu Hospital of Shandong University, Jinan 250012, Shandong Province, China.
Background: Gastrointestinal diseases have complex etiologies and clinical presentations. An accurate diagnosis requires physicians to integrate diverse information, including medical history, laboratory test results, and imaging findings. Existing artificial intelligence-assisted diagnostic tools are limited to single-modality information, resulting in recommendations that are often incomplete and may be associated with clinical or legal risks.
View Article and Find Full Text PDFIEEE Trans Autom Sci Eng
March 2025
H. Milton Stewart School of Industrial and Systems Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Early detection of Alzheimer's Disease (AD) is crucial for timely interventions and optimizing treatment outcomes. Integrating multimodal neuroimaging datasets can enhance the early detection of AD. However, models must address the challenge of incomplete modalities, a common issue in real-world scenarios, as not all patients have access to all modalities due to practical constraints such as cost and availability.
View Article and Find Full Text PDF