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Background: Meniscal ramp lesions can impact knee stability, particularly when associated with anterior cruciate ligament (ACL) injuries. Although magnetic resonance imaging (MRI) is the primary diagnostic tool, its diagnostic accuracy remains suboptimal. We aimed to determine whether deep learning technology could enhance MRI-based ramp lesion detection.
Methods: We reviewed the records of 236 patients who underwent arthroscopic procedures documenting ACL injuries and the status of the medial meniscal posterior horn. A deep learning model was developed using MRI data for ramp lesion detection. Ramp lesion risk factors among patients who underwent ACL reconstruction were analyzed using logistic regression, extreme gradient boosting (XGBoost), and random forest models and were integrated into a final prediction model using Swin Transformer Large architecture.
Results: The deep learning model using MRI data demonstrated superior overall diagnostic performance to the clinicians' assessment (accuracy of 73.3% compared with 68.1%, specificity of 78.0% compared with 62.9%, and sensitivity of 64.7% compared with 76.4%). Incorporating risk factors (age, posteromedial tibial bone marrow edema, and lateral meniscal tears) improved the model's accuracy to 80.7%, with a sensitivity of 81.8% and a specificity of 80.9%.
Conclusions: Integrating deep learning with MRI data and risk factors significantly enhanced diagnostic accuracy for ramp lesions, surpassing that of the model using MRI alone and that of clinicians. This study highlights the potential of artificial intelligence to provide clinicians with more accurate diagnostic tools for detecting ramp lesions, potentially enhancing treatment and patient outcomes.
Level Of Evidence: Diagnostic Level III. See Instructions for Authors for a complete description of levels of evidence.
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http://dx.doi.org/10.2106/JBJS.24.01530 | DOI Listing |
Med Biol Eng Comput
September 2025
Key Laboratory of Mechanism Theory and Equipment Design of Ministry of Education, Tianjin University, Tianjin, 300072, China.
Surgical instrument segmentation plays an important role in robotic autonomous surgical navigation systems as it can accurately locate surgical instruments and estimate their posture, which helps surgeons understand the position and orientation of the instruments. However, there are still some problems affecting segmentation accuracy, like insufficient attention to the edges and center of surgical instruments, insufficient usage of low-level feature details, etc. To address these issues, a lightweight network for surgical instrument segmentation in gastrointestinal (GI) endoscopy (GESur_Net) is proposed.
View Article and Find Full Text PDFAcad Psychiatry
September 2025
University of Toronto, Toronto, Ontario, Canada.
Objective: A deep understanding of patients in psychiatry requires an ability to appreciate and describe the biopsychosocial determinants of health. Great works of theatre portray a nuanced observation of the human condition, but these have not been formally evaluated in psychiatric literature as teaching tools. The purpose of this study was to explore Shakespeare's King Lear as an educational intervention in supporting formulation skills training in geriatric psychiatry residency.
View Article and Find Full Text PDFArch Osteoporos
September 2025
Department of Family Medicine, Chang-Gung Memorial Hospital, Linkou Branch, Taoyuan City, Taiwan.
Unlabelled: The study assesses the performance of AI models in evaluating postmenopausal osteoporosis. We found that ChatGPT-4o produced the most appropriate responses, highlighting the potential of AI to enhance clinical decision-making and improve patient care in osteoporosis management.
Purpose: The rise of artificial intelligence (AI) offers the potential for assisting clinical decisions.
Prog Mol Biol Transl Sci
September 2025
Institute of Intelligent Machines, Chinese Academy of Science, Hefei, Anhui, P.R. China. Electronic address:
The convergence of artificial intelligence (AI) and wearable biosensors is revolutionizing personalized healthcare, enabling continuous monitoring, early detection of health issues, which enhances the efficiency of data processing and real-time decision-making. Multimodal Large Language Models (MLLMs) play a pivotal role in this ecosystem by offering advanced capabilities in analyzing complex health data, understanding nuanced health contexts, and generating tailored health recommendations instantaneously. This study provides insights into how machine learning, deep learning algorithms, and MLLM can work together to facilitate the analysis of physiologic data for real-time monitoring and early warning systems as well as complex decision support mechanisms.
View Article and Find Full Text PDFAm J Ophthalmol
September 2025
Singapore Eye Research Institute, Singapore National Eye Centre, Singapore; Duke-NUS Graduate Medical School, Singapore; Department of Ophthalmology, Emory University School of Medicine, Emory University; Department of Biomedical Engineering, Georgia Institute of Technology/Emory University, Atlanta
Purpose: To characterize the 3D structural phenotypes of the optic nerve head (ONH) in patients with glaucoma, high myopia, and concurrent high myopia and glaucoma, and to evaluate their variations across these conditions.
Design: Retrospective cross-sectional study.
Participants: A total of 685 optical coherence tomography (OCT) scans from 754 subjects of Singapore-Chinese ethnicity, including 256 healthy (H), 94 highly myopic (HM), 227 glaucomatous (G), and 108 highly myopic with glaucoma (HMG) cases METHODS: We segmented the retinal and connective tissue layers from OCT volumes and their boundary edges were converted into 3D point clouds.