A lysosomal fluorescent probe for the imaging of viscosity in tumoral ferroptosis and rheumatoid arthritis mice models.

Chem Commun (Camb)

Institute of Environmental Science, School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan, 030006, P. R. China.

Published: August 2025


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Article Abstract

Viscosity, as an important micro-environment parameter, is closely related to the occurrence and progression of various diseases. Herein, we have developed a novel fluorescent probe (BIB) for lysosomal viscosity detection. Interestingly, using BIB, imaging of viscosity fluctuations in tumoral ferroptosis and rheumatoid arthritis models has been successfully achieved.

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http://dx.doi.org/10.1039/d5cc03040dDOI Listing

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