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Article Abstract
A new phosphinoyl radical precursor, -phosphinoylaminophthalimide (PAPI), was developed. The precursor exhibits several practical advantages: facile synthesis from commercially available starting materials, cost-effectiveness at scale, and excellent air and moisture stability under ambient storage conditions. Phosphinoyl radical was generated under basic and oxidative conditions, and captured by isonitrile and olefin, yielding phosphinoyl-substituted phenanthridines and α-phosphinoyl ketones, respectively. This methodology enables phosphinoyl radical-mediated operationally simple synthesis of organophosphorus compounds.
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-Phosphinoylaminophthalimide: a phosphinoyl radical precursor applied in phosphinoyl-substituted phenanthridine and ketone synthesis.
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School of Chemistry and Chemical Engineering, Zhejiang Sci-Tech University, Xiasha West Higher Education District, Hangzhou, 310018, China.
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Division of Molecular Catalysis and Synthesis, Henan Institute of Advanced Technology, Zhengzhou University, Zhengzhou 450001, P. R. China.
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