98%
921
2 minutes
20
Diffusion models have made remarkable progress in image generation, leading to advancements in the field of image editing. However, balancing editability with faithfulness remains a significant challenge. Motivated by the fact that more novel content will be generated when larger variance noise is applied to the image, in this paper, we propose an Enhanced Non-isotropic Gaussian Diffusion Model (ENGDM) for progressive image editing, which introduces independent Gaussian noise with varying variances to each pixel based on its editing needs. To enable efficient inference without retraining, ENGDM is rectified into an isotropic Gaussian diffusion model (IGDM) by assigning different total diffusion times to different pixels. Furthermore, we introduce reinforced text embeddings, using a novel editing reinforcement loss in the latent space to optimize text embeddings for enhanced editability. And we introduce optimized noise variances by employing a structural consistency loss to dynamically adjust the denoising time steps for each pixel for better faithfulness. Experimental results on multiple datasets demonstrate that ENGDM achieves state-of-the-art performance in image-editing tasks, effectively balancing faithfulness to the source image and alignment with the desired editing target.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12114899 | PMC |
http://dx.doi.org/10.3390/s25102970 | DOI Listing |
Anal Chim Acta
November 2025
College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, China. Electronic address:
Background: The development of specific fluorescent probes for cancer cell discrimination holds significant promise for advancing cancer diagnostics. Conventionally, these probes operate by translating differences in biomarkers or microenvironmental factors into variations in whole-cell fluorescence intensity. However, this dominant, intensity-based strategy is highly susceptible to extraneous fluctuations arising from probe concentration, illumination instability and complex intracellular environment.
View Article and Find Full Text PDFJ Colloid Interface Sci
September 2025
Institute of Biomedical Engineering, College of Medicine, Key Laboratory of Advanced Technologies of Materials, Ministry of Education, Southwest Jiaotong University, Chengdu 610031, PR China. Electronic address:
Pyroelectrodynamic therapy (PEDT) of tumors faces challenges due to its low electrocatalytic efficiency at mild temperature and the potential for off-target toxicity to healthy tissue. To overcome these issues, we have engineered pyroelectric nanoparticles (NPs) that feature a pH-triggered heterojunction structure and tumor-selective reactive oxidative species (ROS) production, faclitating synergistic PEDT and mild photothermal therapy (PTT). Herein, molybdenum trioxide (MoO) was deposited in-situ on the surface of tetragonal BaTiO (tBT) to create tBT@MO.
View Article and Find Full Text PDFComput Biol Med
September 2025
Laboratorio de Procesado de Imagen (LPI), ETSI Telecomunicación, Universidad de Valladolid, Valladolid, Spain. Electronic address:
Modelling the diffusion-relaxation magnetic resonance (MR) signal obtained from multi-parametric sequences has recently gained immense interest in the community due to new techniques significantly reducing data acquisition time. A preferred approach for examining the diffusion-relaxation MR data is to follow the continuum modelling principle that employs kernels to represent the tissue features, such as the relaxations or diffusion properties. However, constructing reasonable dictionaries with predefined signal components depends on the sampling density of model parameter space, thus leading to a geometrical increase in the number of atoms per extra tissue parameter considered in the model.
View Article and Find Full Text PDFMagn Reson Med
September 2025
Laboratorio de Procesado de Imagen (LPI), Universidad de Valladolid, Valladolid, Spain.
Purpose: (a) To design a methodology for drawing random samples of any Ensemble Average Propagator (EAP) (b) to modify the KomaMRI simulator to accommodate them as realistic spin movements to simulate diffusion MRI (dMRI) and (c) to compare these simulations with those based on the Diffusion Tensor (DT) model.
Theory And Methods: The rejection method is used for random sampling of EAPs: starting from a probability law that is easily sampled, and whose density function wraps the target EAP, samples are accepted when they lie inside the targeted region. This is used to sample the EAP as described by Mean Apparent Propagator MRI (MAP-MRI) and in Spherical Convolution (SC) based on Spherical Harmonics (SH).
Ann Plast Surg
September 2025
From the Department of Plastic Surgery, Vanderbilt University Medical Center, Nashville, TN.
Diffusion tensor imaging (DTI) has revolutionized neuroimaging by enabling a noninvasive visualization of tissue microstructure through the analysis of the apparent diffusion of water molecules. Originating from the foundational principles of Brownian motion and Fick's law, DTI evolved from early diffusion magnetic resonance imaging into an advanced diagnostic tool for in vivo characterization of axonal pathways. This review traces the historical development of DTI and evaluates its expanding clinical applications, particularly in assessing peripheral nerve pathologies.
View Article and Find Full Text PDF