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Study Design: Qualitative analysis study.
Introduction: Social media has been pivotal in the dissemination of medical knowledge to the public. The aim was to identify the demographics of individuals posting about cleft lip and palate on YouTube Shorts and Instagram, to characterize the content of these posts, and to highlight factors that could aid surgeons in better educating patients with cleft lip and palate.
Methods: Instagram posts and YouTube Shorts with "#cleftlip", "#cleftawareness", "#cleftpalate", "#cleftplipandpalate", and "#cleftproud" were searched on 8 June 2024. Postings were subclassified and analyzed for content, including topics of posts, authors, media type, tone of the post, and year of post.
Results: A total of 3321 posts were analyzed, with 2698 coming from Instagram and 623 from YouTube Shorts. The majority of content creators were patients and their family members ( = 2054, 61.8%), cleft lip and palate foundations ( = 384, 11.6%), and companies ( = 381, 11.5%). Only 167 posts were authored by physicians (5.1%). Among the educational and informational posts, patients and family members accounted for the majority of the posts (409 posts, 57.7%). Physicians contributed to a small fraction of the educational content (37 posts, 5.2%).
Conclusions: Physician participation in the cleft lip and palate social media realm on Instagram and YouTube Shorts was found to be limited. Moreover, there was a scarcity of educational content on both platforms, indicating a significant opportunity for physicians to engage more actively in cleft lip and palate social media discussions.
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http://dx.doi.org/10.3390/cmtr18010004 | DOI Listing |
Oral Dis
September 2025
Department of Oral Diagnosis, School of Dentistry, University of Campinas (FOP/UNICAMP), Piracicaba, Brazil.
Ann Epidemiol
September 2025
School of Public Health, Peking University, Beijing, China. Electronic address:
Purpose: We estimated the association between maternal sexually transmitted diseases (STDs) and the risk of specific birth defects among live singleton births in the United States (US).
Methods: We conducted a population-based study using data from birth certificates for 14,602,822 live singleton births occurring from 2016 to 2019 in the US. We used logistic regression to estimate the associations between three maternal STDs (chlamydia, gonorrhea, and syphilis) and the risk of four specific birth defects (gastroschisis, cleft lip with or without cleft palate, spina bifida, and hypospadias), adjusting for socio-demographic and pregnancy-related factors.
J Clin Res Pediatr Endocrinol
September 2025
İnönü University Faculty of Medicine, Department of Medical Genetics, Malatya, Türkiye.
CHARGE syndrome is an autosomal dominant disorder caused by variations in the CHD7 gene. The characteristic findings of the syndrome include coloboma (C), heart anomalies (H), choanal atresia (A), growth and developmental delay (R), genitourinary system anomalies (G), and ear anomalies and/or hearing loss (E). A 7.
View Article and Find Full Text PDFALTEX
August 2025
Department of Biomedical Engineering, Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, MI, USA.
Sonic hedgehog (SHH) is a major intercellular signaling pathway involved in the orchestration of embryogenesis, including orofacial morphogenesis. The SHH pathway is sensitive to disruption, including both genetic predisposition and chemical-induced disruption at multiple molecular targets including antagonism of the SHH signal transducer Smoothened (SMO). Here we report the adverse outcome pathway (AOP) 460 describing the linkage between antagonism of the SMO receptor, a key intermediate in the hedgehog signaling, and orofacial clefts (OFCs).
View Article and Find Full Text PDFChild Care Health Dev
September 2025
Population Health Research Institute, St George's, University of London, London, UK.
Background: Parents and carers of children with congenital anomalies can experience stress when managing their child's healthcare needs. It is important that they are well supported. This study explored the support needs of parents/carers of children with a congenital anomaly across Europe.
View Article and Find Full Text PDF