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Since the beginning of the COVID-19 pandemic, moral distress among healthcare workers in the Intensive Care Unit (ICU) has garnered both media and academic attention. Moral distress has been theorized as occurring when individuals are constrained from doing what they perceive as morally right. This study sought to empirically examine the lived experiences of moral distress among clinical and administrative healthcare professionals in a sample of Canadian ICUs during the COVID-19 pandemic. Qualitative case study methodology was used as the overarching approach, collecting and comparing data from two distinct cases: one ICU in Ontario and one in Alberta. Data collection involved two primary sources: semi-structured interviews with staff and document review of institutional and government directives to provide contextual data. Data analysis commenced concurrently with data collection, and generated within- and across-case themes, as well as allowed descriptive accounts of moral distress. Thirty-six healthcare workers across two sites were interviewed. Participants described three primary categories of constraints leading to moral distress. These were: 1) The rapidity and opaqueness of policy development, specifically pertaining to 2) the implementation of family visitation and treatment triage decisions, and 3) resource shortages, which reduced patient interactions, shifted professional responsibilities. Each of these constraints yielded circumstances and forced decisions that were perceived as morally wrong because they compromised care quality and outcomes. While sharing similarities with the growing literature on moral distress in the context of the COVID-19 pandemic, this study reveals new insights on how provincial and institutional policy has direct bearing on experiences of moral distress. Policies and circumstances forced ICU staff to choose between actions they considered the most right and the least wrong. Understanding these specific policy-driven constraints highlights the need for healthcare systems and processes that mitigate moral distress and sustain our health workforce.
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http://dx.doi.org/10.1177/08850666251329828 | DOI Listing |
PLoS One
September 2025
Institute of Laboratory Animal Science, Medical Faculty, Heinrich-Heine-University, Duesseldorf, Germany.
Early-career researchers (ECRs) play a key role in conducting animal experiments in academic research. However, they face considerable challenges, including poor working conditions, and inadequate strategies for managing distress. These difficulties are often amplified in animal research, where a lack of consensus on the 3Rs (replacement, reduction, and refinement), challenges to navigate complex regulations and ethical dilemmas can further complicate the situation.
View Article and Find Full Text PDFBioscience
September 2025
South African National Biodiversity Institute, Kirstenbosch Research Centre, Cape Town.
Conservation policies often need to integrate scientific predictions with ethical considerations. However, different normative ethical systems at the root of conservation approaches often support different decisions, and the moral stances of stakeholders are influenced by diverse societal values and perceptions. This creates the potential for dilemmas and conflicts.
View Article and Find Full Text PDFGlob Bioeth
September 2025
EXUS AI Labs, Athens, Greece.
The ethical complexities of technological advancement are growing as fields such as climate adaptation, microbiology, healthcare, robotics, and artificial intelligence (AI) evolve rapidly. While these technologies offer innovative solutions to global challenges, they raise significant ethical concerns. In climate adaptation, AI-driven models and remote sensing technologies prompt questions about data privacy, environmental justice, and equitable access, especially for vulnerable populations.
View Article and Find Full Text PDFOpen Med (Wars)
August 2025
Department of Burns and Wound Repair, Weifang People's Hospital, Shandong Second Medical University, Weifang, China.
Objective: Hypertrophic scars (HS) are a fibrotic proliferative disorder that results from an abnormal wound healing process, presenting significant challenges for clinical intervention. The primary characteristics of HS include excessive collagen deposition and angiogenesis. In recent years, the study of mesenchymal stem cells (MSCs) and their derived exosomes has emerged as a prominent area of research within the academic community.
View Article and Find Full Text PDFPaediatr Child Health
August 2025
Department of Paediatrics, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Every paediatrician's career includes the provision of care for children with life-limiting conditions. The College of Physicians and Surgeons of Ontario published a revised policy, "Decision-making for End-of-Life Care," in March 2023; in this commentary we explore the ramifications of this policy for community and acute care paediatricians in Ontario and highlight principles to contextualize this beyond provincial borders. In particular we discuss its impact upon clinicians' moral distress and the importance of: i) early and longitudinal engagement with patients and families, where possible, to contextualize the role of resuscitative measures (if any) in addition to the many other important considerations concerning high quality end-of-life care; and ii) preventing bias and calibrating decision-making with clinical colleagues (including Bioethics) to ensure CPR is never withheld because of a child's such as their race, age, or disability.
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