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In forensic practice, multiple sinuses of Valsalva Aneurysm resulting in death have rarely been reported. Here, we present the case of a 55-year-old man who was admitted to hospital with vomiting and recurrent abdominal pain. Ultrasonography showed that the aorta non-coronary sinus had an expansion to the right atrium with a range of about 19mm × 16mm and a rupture at the top of the aorta with a width of about 5mm. The movement of the left ventricular wall was uncoordinated. During the autopsy, forensic scientists found that the deceased also had a right coronary sinus of the aorta. To be exact, the wall of the aorta at the bottom was enlarged in a tuberous manner and bulged into the right ventricular outflow tract, partially obstructing the right ventricular outflow tract. The cause of death was considered to be acute right heart failure caused by the sinus of Valsalva Aneurysm complicated with the non-coronary sinus aneurysm puncturing into the right atrium, followed by multiple organ failure. In cases of unexplained death, the sinus of the Valsalva Aneurysm should be carefully examined because the aneurysm may be asymptomatic and the possibility of rupture cannot be ignored. This case demonstrated an effective post-mortem diagnostic entity and highlights the significance of post-mortem examination in dealing with unexplained deaths.
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http://dx.doi.org/10.1016/j.jflm.2025.102860 | DOI Listing |
Multimed Man Cardiothorac Surg
September 2025
Departments of Cardiothoracic Surgery, Mansoura University, Mansoura, Egypt
We present a 62-year-old female with severe aortic valve regurgitation and a ruptured large sinus of Valsalva aneurysm. The aneurysm was resected in its entirety. A single-leaflet aortic valve reconstruction combined with a left coronary sinus aortic root replacement (hemi-Yacoub procedure) was performed with success.
View Article and Find Full Text PDFJACC Case Rep
August 2025
Department of Cardiology, Heart Valve Center Mainz, University Medical Center Mainz, Mainz, Germany.
Background: Aortic sinus aneurysm rupture is a rare event (<1% of congenital cardiac lesions); however, it varies geographically and by population.
Case Summary: A 56-year-old man presented with symptoms of heart insufficiency and chest pain. Transthoracic echocardiography showed a blow passage between the right coronary sinus and the right ventricular outflow tract.
Cureus
July 2025
Department of Cardiac Surgery, Ippokrateio General Hospital of Athens, Athens, GRC.
Giant aortic root aneurysms are rare and potentially life-threatening, especially when the diameter exceeds 10 cm. These cases require urgent surgical intervention and pose significant technical challenges due to the risk of rupture, distorted anatomy, and associated valve dysfunction. We report the case of a 58-year-old man who presented with acute chest pain and refractory hypertension.
View Article and Find Full Text PDFJACC Case Rep
August 2025
Department of Cardiovascular and Thoracic Surgery, University of Louisville School of Medicine, Louisville, Kentucky, USA. Electronic address:
Background: Sinus of Valsalva aneurysm is a rare condition that can cause acute heart failure once it develops a fistula.
Case Summary: A previously healthy 28-year-old man without history of intravenous drug use initially presents with an acute onset of heart failure symptoms. Transthoracic echocardiogram transesophageal echocardiogram revealed an aorto-atrial fistula causing significant left-to-right shunting.
J Invasive Cardiol
August 2025
Department of Echocardiography, Wuhan Asia Heart Hospital Affiliated Wuhan University of Science and Technology, Wuhan, P.R. China. Email: