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Introduction: This study aimed to examine the effects of a positive psychological intervention, grounded in the PERMA model, on fear levels, psychological capital, overall well-being, and quality of life among stroke patients.
Methods: A single-blind, two-arm randomized controlled trial with a repeated measures design was conducted at the Affiliated Hospital of Jiangnan University from January to December 2023. A total of 125 patients experiencing fear of stroke recurrence were randomly assigned to either the intervention group ( = 63), which received a positive psychological intervention based on the PERMA model, or the control group ( = 62), which received standard care. We assessed fear levels, psychological capital, well-being, and quality of life at baseline (T0), on the day of discharge (T1), 2 weeks post-discharge (T2), and 4 weeks post-discharge (T3). The scores of the two groups were compared post-intervention using the Generalized Estimation Equation (GEE) model to analyze the effects of time, group membership, and their interaction.
Results: The intervention group showed statistically significant improvements compared to the control group, including reduced fear levels (T2: = -2.094, = 0.038; T3: = -2.207, = 0.029), increased psychological capital (T2: = 2.053, = 0.042; T3: = 2.820, = 0.006), enhanced well-being (T2: = 2.037, = 0.044; T3: = 2.761, = 0.007), and better quality of life (T2: = 2.083, = 0.039; T3: = 2.453, = 0.016) at both T2 and T3. Additionally, significant time-related changes were observed in fear levels, psychological capital, well-being, and quality of life (χ2 = 45.275, < 0.001; χ2 = 37.848, < 0.001; χ2 = 48.255, < 0.001; χ2 = 34.231, < 0.001, respectively). Notably, the interaction effects were statistically significant for well-being ( < 0.05).
Discussion: The PERMA-based intervention had a short-term positive effect, reducing fear levels while enhancing psychological capital, well-being, and quality of life among stroke patients.
Clinical Trial Registration: https://www.chictr.org.cn/showproj.html?proj=230313.
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http://dx.doi.org/10.3389/fpsyg.2025.1498078 | DOI Listing |
Open Life Sci
September 2025
Physiology and Physiopathology Team, Faculty of Sciences, Genomic of Human Pathologies Research Centre, Mohammed V University in Rabat, Rabat, Morocco.
The legalization of cannabis for industrial and medicinal purposes has significantly expanded worldwide. This study delves into the analgesic potential toxicity study of chloroformic extract from the Moroccan L. () cultivar, Khardala (KH extract).
View Article and Find Full Text PDFNan Fang Yi Ke Da Xue Xue Bao
August 2025
School of Traditional Chinese Medicine, Henan University of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China.
Objectives: To investigate the impact of prenatal fear stress on placental amino acid transport and emotion and cognition development in offspring rats.
Methods: Thirty pregnant Wistar rats were randomized equally into control and fear stress (induced using an observational foot shock model) groups. In each group, placental and serum samples were collected from 6 dams on gestational day 20, and the remaining rats delivered naturally and the offspring rats were raised under the same conditions until 8 weeks of age.
Reprod Health
September 2025
Department of Sexual and Reproductive Health including UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction, World Health Organization, Avenue Appia 20, 1211, Geneva, Switzerland.
Background: The COVID-19 pandemic disrupted the provision of sexual and reproductive health services, including contraceptive and family planning (FP) services. The World Health Organization conducted a multi-country study in India, Nigeria and Tanzania to assess the impact of the pandemic on the health system's capacity to provide contraceptive and FP services. In this paper, we share the results of a qualitative study aimed at understanding clients' perspectives at the primary healthcare level on accessing contraceptive services in COVID-19-affected areas in the three aforementioned countries.
View Article and Find Full Text PDFJ Prof Nurs
September 2025
University of Pittsburgh School of Nursing, United States of America. Electronic address:
Background: Failure to fail involves assigning passing grades to students who have not achieved course or clinical objectives at a satisfactory level. The literature has shown that this phenomenon occurs more frequently in the clinical setting due to several issues, including the increased subjectivity of clinical evaluation tools and processes, unclear policies, and lack of administrative support to fail students. The question remains: What is the thought process that is used by faculty to determine if a student passes or fails in a clinical experience?
Purpose: To explore the decision-making process used by pre-licensure clinical nursing faculty when they are determining whether to pass or fail an unsafe student enrolled in a clinical course.
J Ethnopharmacol
September 2025
Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, Guizhou Province, China. Electronic address:
Ethnopharmacological Relevance: Gastrodia elata, also known as Chijian, belongs to the Orchidaceae family of plants. The "Compendium of Materia Medica" records that Gastrodia elata treats "confused speech, excessive fear, and loss of willpower". Gastrodin (GAS) is the main bioactive component of Gastrodia elata.
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