98%
921
2 minutes
20
In recent years, a kind of novel cellular concrete, fabricated by spherical saturated superabsorbent polymers, was developed. Its compressive behavior under high strain rate loadings has been studied by split Hopkinson pressure bar equipment in previous research, which revealed an obvious strain rate effect. It has been found by many researchers that the dynamic increase factor (DIF) of compressive strength for concrete-like materials measured by SHPB includes considerable structural effects, which cannot be considered as a genuine strain rate effect. Based on the extended Drucker-Prager model in Abaqus, this paper uses numerical SHPB tests to investigate structural effects in dynamic compression for this novel cellular concrete. It is found that the increment in compressive strength caused by lateral inertia confinement decreases from 5.9 MPa for a specimen with a porosity of 10% to 2 MPa for a specimen with a porosity of 40% at a strain rate level of 70/s, while the same decreasing trend was found at other strain rate levels of 100/s and 140/s. The lateral inertia confinement effect inside the cellular concrete specimen can be divided into the elastic development stage and plastic development stage, bounded by the moment dynamic stress equilibrium is achieved. The results obtained in this research can help to obtain a better understanding of the enhancement mechanism of the compressive strength of cellular concrete.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11818655 | PMC |
http://dx.doi.org/10.3390/ma18030552 | DOI Listing |
Antiviral Res
September 2025
State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730030, P.R. China; Yazhouwan National Laboratory, Sanya 572024, P. R. China. Electronic addres
Due to the lack of timely vaccine prevention and effective drug treatment, lumpy skin disease is increasingly becoming a global epidemic, including in China. There is an urgent need to explore the pathogenic mechanism of lumpy skin disease virus (LSDV) and develop practical therapeutic approaches. The present study provides concrete evidence for the simultaneous induction and activation of nuclear ATM-mediated double-strand break and ATR kinase-dependent single-strand break signaling cascades during LSDV replication in the cytoplasm.
View Article and Find Full Text PDFAAPS J
September 2025
Precision Medicine Bioanalytical & Translational Sciences, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, NJ, 08543, USA.
CAR-T-cells can drive MHC class-I-mediated CD8 + cytotoxic T-cell response towards CAR constructs in addition to an antibody response. Immune response may also develop towards residuals present in the CAR-T cell product such as AAV, CRISPR/CAS9, and expamers. Health authorities recommend developing assays to assess both humoral and cellular immunogenicity towards the CAR-T protein.
View Article and Find Full Text PDFMethodsX
December 2025
Department of Civil Engineering, KSR College of Engineering, Tiruchengode, Tamilnadu, India.
This study investigates the durability enhancement of bacterial concrete incorporating microbial strains (Bacillus Licheniformis, Bacillus Flexus, Pseudomonas stutzeri, Escherichia coli, and Bacillus subtilis) through microbial-induced calcium carbonate precipitation (MICP). Various durability tests, including water absorption, RCPT, sulphate resistance, hydrochloric acid strength loss, sorptivity, and energy-dispersive X-ray analysis (EDAX), were conducted to evaluate the effectiveness of bacterial concrete. Bacterial concrete significantly reduces water absorption and chloride ion penetration, with Bacillus subtilis (M16) and Bacillus Flexus (M7) demonstrating the highest impermeability.
View Article and Find Full Text PDFAnal Methods
September 2025
School of Pharmacy, Binzhou Medical University, Yantai 264003, China.
Sulfur dioxide (SO), an important gaseous signaling molecule, takes part in multiple pathological and physiological processes and plays a vital role in complex biological systems. However, the pathogenesis of many serious diseases, such as respiratory diseases, cardiovascular disorders and neurological diseases, resulting from excessive inhalation of SO remains unclear. Therefore, it is significant to develop reliable analytical methods to effectively and concretely monitor SO derivatives in living systems.
View Article and Find Full Text PDFJ Gen Virol
August 2025
Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, 430071, PR China.
The highly pathogenic Nipah virus (NiV), a World Health Organization priority pathogen with pandemic potential, remains a critical public health threat due to its capacity to cause fatal encephalitis and respiratory disease. Despite its 1998 emergence, no approved therapeutics exist against NiV infection, underscoring the urgent need to identify genomic regulatory elements as antiviral targets. Our study focuses on the extended 5' UTRs characteristic of NiV transcripts, a distinctive genomic feature whose functional significance remained enigmatic.
View Article and Find Full Text PDF