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The development of high-performance strains and the continuous breakthrough of strain screening technology also pose challenges to downstream fermentation optimization and scale-up. Therefore, neural network models are utilized to optimize the fermentation process to meet the goals of boosting yield or lowering cost, with the use of artificial intelligence technology in conjunction with the peculiarities of the fermentation process. High-performance strains' yield rise and fermentation process amplification will be sped up with the aid of neural network models. This paper offers a helpful review for anyone interested in state-of-the-art microbial fermentation processes, as it thoroughly reviews the application of neural network models in predicting fermentation yield, optimizing the fermentation process, and monitoring the fermentation process.
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http://dx.doi.org/10.1016/j.biortech.2024.131801 | DOI Listing |
J Agric Food Chem
September 2025
School of Food & Biological Engineering, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013 Jiangsu Province, China.
Pectinases are indispensable biocatalysts for pectin degradation in food and bioprocessing industries, yet natural enzymes often lack tailored functionalities for modern applications. While a previous review discussed pectinases in terms of production and application, this review particularly discusses an integrated framework for robust pectinases. This framework combines enzyme mining, protein engineering, and AI-assisted design to systematically discover, optimize, and customize pectinases.
View Article and Find Full Text PDFBiotechnol Rep (Amst)
September 2025
Technical University of Munich, Germany, TUM Campus Straubing for Biotechnology and Sustainability, Bioprocess Engineering, Uferstraße 53, D-94315 Straubing, Germany.
Exopolysaccharides are biopolymers with wide-ranging industrial applications. To substitute fossil-based by bio-based, biodegradable polymers, exopolysaccharide production needs to become much more efficient. Pullulan, produced by , is popular for its unique properties like film-formation, adhesiveness, biodegradability, etc.
View Article and Find Full Text PDFMicrobiologyopen
October 2025
Department of Biochemistry, Faculty of Science and Technology, Chiromo Campus, Off Riverside Drive, University of Nairobi, Nairobi, Kenya.
Alkaline pectinases are in demand in industrial processes that require the degradation of plant pectins at high pH, for example, removal of pectin stains from fabrics, cutlery, and porcelain; treatment of pectic wastewater; fermentation of coffee, tea, and cocoa; manufacture of poultry and animal feeds, and processing of textiles, and so forth. The present study aimed to (a) screen four alkaliphilic microbial isolates, previously obtained from samples collected around Lake Bogoria (soda lake), Baringo County, Kenya, for alkaline pectinases, and (b) characterize the pectinase-producers. The screening data revealed that all the isolates were pectinase producers, exhibiting catalytic activities that ranged from 1.
View Article and Find Full Text PDFFood Res Int
November 2025
Faculdade de Engenharia de Alimentos (FEA), Universidade Estadual de Campinas (UNICAMP), Rua Monteiro Lobato, 80, 13083-862, Campinas, São Paulo, Brazil. Electronic address:
The hydrolysis of biomass in fermentative processes often faces the difficulty of generating inhibitory products. Its reduction or removal is essential to enable the use of agro-industrial waste, such as cashew apple bagasse. Therefore, this study aimed to find an optimized condition for the hydrolysis of cashew apple bagasse by subcritical water and to introduce an in-line pre-purification process.
View Article and Find Full Text PDFFood Res Int
November 2025
College of Food Science and Engineering, Gansu Agricultural University, Lanzhou, China. Electronic address:
In this study, yak bone collagen peptide-tea polyphenol binding peptides (YCP/TP) were successfully prepared and investigated for their positive effects in replacing nitrite to improve the color, texture, flavor and bacterial community structure of fermented sausages. Results showed that YCP/TP primarily binds through hydrogen bond interactions, enhancing its stability and functional properties. The YCP/TP can effectively inhibit the increase in pH, protein carbonyls and TBARS (p < 0.
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