Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Ferritin (Ft) is a protein with a peculiar three-dimensional architecture. It is characterized by a hollow cage structure and is responsible for iron storage and detoxification in almost all living organisms. It has attracted the interest of the scientific community thanks to its appealing features, such as its nano size, thermal and pH stability, ease of functionalization, and low cost for large-scale production. Together with high storage capacity, these properties qualify Ft as a promising nanocarrier for the development of delivery systems for numerous types of biologically active molecules. In this paper, we introduce the basic structural and functional aspects of the protein, and summarize the methods employed to load bioactive molecules within the ferritin nanocage.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11396501 | PMC |
| http://dx.doi.org/10.3390/molecules29174045 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Recent advances in the discovery of novel bleaching herbicides inspired by natural products.
Pestic Biochem Physiol
November 2025
Department of Chemistry, College of Arts and Sciences, Northeast Agricultural University, Harbin 150030, China; Key Laboratory of Agricultural Functional Molecule Design and Utilization of Heilongjiang Province, Northeast Agricultural University, Harbin 150030, China. Electronic address:
Pigment biosynthesis serves as a fundamental physiological process vital for weeds survival. Disruption of this pathway leads to the depletion of critical pigments, ultimately resulting in weeds death. Consequently, pigment biosynthesis has become a valuable target in modern herbicide development.
View Article and Find Full Text PDFPerioperative neurocognitive disorders: Advances in molecular mechanisms and bioactive molecules.
Ageing Res Rev
September 2025
Institute for Cerebrovascular and Neuroregeneration Research (ICNR), Department of Neurology, LSU Health Shreveport, 1501 Kings Hwy, Shreveport, LA 71103, USA. Electronic address:
Perioperative neurocognitive disorders (PNDs) are common complications following surgery, especially in elderly patients, and are characterized by memory loss, attention deficits, and impaired executive function. The pathogenesis of PNDs involves a complex interplay of neuroinflammation, neurotransmitter imbalance, epigenetic modifications, and gut-brain axis disruption. This review summarizes the latest findings on the mechanisms underlying PNDs, with a focus on microglial activation, interleukin imbalance, and NLRP3 inflammasome-mediated pyroptosis.
View Article and Find Full Text PDFMechanically robust and highly conductive polyacrylamide/carboxymethyl chitosan organohydrogels via synergistic physical interactions for flexible sensing.
Int J Biol Macromol
September 2025
College of Materials Science and Engineering, Nanjing Tech University, Nanjing, 210009, China.
Conductive hydrogels have revolutionized wearable electronics due to their biocompatibility and tunable properties. However, it remains a great challenge for hydrogel-based sensors to maintain both conductivity and mechanical integrity in harsh environments. Synergistic dynamic interactions provide a promising strategy to address this issue.
View Article and Find Full Text PDFScorpion Venom Gland Transcriptomics: A Systematic Review.
Toxicon
September 2025
Grupo Infección e Inmunidad, Departamento de Ciencias Básicas, Facultad de Ciencias de la Salud, Universidad Tecnológica de Pereira, Pereira, Colombia. Electronic address:
Scorpion venom is a complex biochemical arsenal with significant ecological and biomedical importance. Advances in transcriptomic techniques have provided valuable insights into the composition and functional diversity of venoms. This systematic review analyzes transcriptomic research conducted between 2010 and 2024, focusing on methodologies such as Expressed Sequence Tags (ESTs) and Next-Generation Sequencing (NGS).
View Article and Find Full Text PDFHeterogeneous nuclear ribonucleoprotein A/B drives gastric cancer and epithelial-mesenchymal transition via the Akt-GSK3β-Wnt pathway.
Mol Pharmacol
September 2025
State Key Laboratory of Bioactive Molecules and Druggability Assessment, Institute of Genomic Medicine, International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), College of Pharmacy, Jinan University, Gu
Gastric cancer (GC) is a leading cause of cancer-related deaths globally, with metastasis critically impacting prognosis. Splicing factors are key regulators of tumorigenesis, particularly in metastasis. In this exploratory study, we investigated the role and mechanism of heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB) in GC cell invasion and migration.
View Article and Find Full Text PDF