Construction of cationic -thiazolium-BODIPY AIE fluorescent probes for viscosity imaging in dual organelles.

Chem Commun (Camb)

Center for Advanced Analytical Science, Guangzhou Key Laboratory of Sensing Materials and Devices, Guangdong Engineering Technology Research Center for Photoelectric Sensing Materials and Devices, c/o School of Chemistry and Chemical Engineering, Guangzhou University, Guangzhou 510006, P. R. China.

Published: August 2024


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Article Abstract

Two new cationic -thiazolium-BODIPY-based water-soluble and red-shifted fluorescent probes were constructed for the first time. They can monitor cellular viscosity in dual organelles and show aggregation-induced emission (AIE), which is ascribed to the efficient restricted rotation of -thiazolium in viscous or hindered systems. Probe 3 with an -benzyl group shows better AIE as compared to probe 2 with an -methyl group.

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http://dx.doi.org/10.1039/d4cc02977aDOI Listing

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