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Traditional optical waveguides or mediums are often silica-based materials, but their applications in biomedicine and healthcare are limited due to the poor biocompatibility and unsuitable mechanical properties. In term of the applications in human body, a biocompatible hydrogel system with excellent optical transparency and mechanical flexibility could be beneficial. In this review, we explore the different designs of hydrogel-based optical waveguides derived from natural and synthetic sources. We highlighted key developments such as light emitting contact lenses, implantable optical fibres, biosensing systems, luminating and fluorescent materials. Finally, we expand further on the challenges and perspectives for hydrogel waveguides to achieve clinical applications.
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http://dx.doi.org/10.1016/j.bioactmat.2024.03.031 | DOI Listing |
Nano Lett
September 2025
Department of Materials Science and Engineering, Seoul National University, Seoul 08826, South Korea.
Seamless integration of active devices into photonic integrated circuits remains a challenge due to the limited accessibility of the optical field in conventional waveguides, which tightly confine light within their cores. In this study, we propose a two-dimensional (2D) ultrathin waveguide as a photonic platform that enables efficient interaction between guided light and surface-mounted devices by supporting optical modes dominated by evanescent fields. We show that the guided light in a monolayer MoS film propagates over millimeter-scale distances with more than 99.
View Article and Find Full Text PDFJ Phys Chem B
September 2025
Department of Physics, Division of Nano and Biophysics, Chalmers University of Technology, Fysikgränd 3, Göteborg 41296, Sweden.
The detection of biological nanoparticles (NPs), such as viruses and extracellular vesicles (EVs), plays a critical role in medical diagnostics. However, these particles are optically faint, making microscopic detection in complex solutions challenging. Recent advancements have demonstrated that distinguishing between metallic and dielectric signals with twilight off-axis holographic microscopy makes it possible to differentiate between metal and biological NPs and to quantify complexes formed from metal and biological NPs binding together.
View Article and Find Full Text PDFJ Am Chem Soc
September 2025
Center for Nanochemistry, Beijing Science and Engineering Center for Nanocarbons, Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.
Incorporating atomically thin two-dimensional (2D) materials with optical fibers expands their potential for optoelectronic applications. Recent advancements in chemical vapor deposition have enabled the batch production of these hybrid fibers, paving the way for practical implementation. However, their functionality remains constrained by the integration of a single 2D material, restricting their versatile performance.
View Article and Find Full Text PDFNanoscale
September 2025
Department of Chemistry, Kyung Hee University, Seoul 02447, Korea.
Highly efficient optoelectronic devices of ultrasmall sizes are demanded as building blocks of next-generation integrated circuits, where tunable color enhances the feasibility of various applications. Here, we realize tunable multicolor nanolasers using disk-shaped axial heterostructures composed of III-nitride materials (GaN/InGaN/GaN), leveraging the optical confinement effect and active waveguiding. In heterostructure nanodisks, the development of exciton-polariton induces unique features near the resonance regime, and the formation of whispering-gallery modes facilitates optical gain processes for the polaritonic lasing of GaN.
View Article and Find Full Text PDFLab Chip
September 2025
State Key Laboratory of Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun 130012, China.
Photonic crystal slow light waveguides present a breakthrough in the manipulation of optical signals and enhancing the interaction between light and matter. In particular, two-dimensional (2D) photonic crystal waveguides (PCWs) on silicon photonic chips hold promise in improving the sensitivity of on-chip gas sensors. However, the development of the gas sensors based on 2D PCWs suffers from a high propagation loss and a narrow slow light bandwidth.
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