Two new acorane-type sesquiterpenoids from an endophytic associated with Pall.

Nat Prod Res

School of Pharmacy, Anhui University of Chinese Medicine, Anhui Province Key Laboratory of Research & Development of Chinese Medicine, Hefei, P.R. China.

Published: July 2025


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Article Abstract

Two new acorane-type sesquiterpenoids, harzianes A and B ( and ), together with two known cyclonerodiol-type sesquiterpenoids (-) and four known sterols (-) were isolated from the endophytic , associated with the medicinal plant Pall. Compounds and were identified as a pair of heterotropic isomers by spectroscopic analysis (HR-ESI-MS, 1D and 2D NMR), and their absolute configurations were determined by ECD calculations. All compounds were tested for anti-inflammatory activity, however, none demonstrated such activity.

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http://dx.doi.org/10.1080/14786419.2024.2308001DOI Listing

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