Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Anthraquinone dyes are the second most important type of dyes after azo dyes. In particular, 1-aminoanthraquinone has been extensively utilized in the preparation of diverse anthraquinone dyes. This study employed a continuous-flow method to synthesize 1-aminoanthraquinone safely and efficiently through the ammonolysis of 1-nitroanthraquinone at high temperatures. Various conditions (reaction temperature, residence time, molar ratio of ammonia to 1-nitroanthraquinone (), and water content) were investigated to explore the details of the ammonolysis reaction behavior. Operation conditions for the continuous-flow ammonolysis were optimized using Box-Behnken design in the response surface methodology, and ~88% yield of 1-aminoanthraquinone could be achieved with an of 4.5 at 213 °C and 4.3 min. The developed process's reliability was evaluated by performing a 4 h process stability test. The kinetic behavior for the preparation of 1-aminoanthraquinone was investigated under continuous-flow mode to guide the reactor design and to gain a deeper understanding of the ammonolysis process.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254563 | PMC |
| http://dx.doi.org/10.3390/molecules28114314 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Long Term Outcomes of Tricuspid Valve Repair or Replacement in Patients with Continuous Flow Left Ventricular Assist Devices.
J Thorac Cardiovasc Surg
September 2025
Division of Cardiac, Thoracic & Vascular Surgery, Department of Surgery, Columbia University Irving Medical Center, NewYork-Presbyterian Hospital, New York, NY. Electronic address:
Objective: Our objective was to determine the long-term outcomes of concomitant tricuspid valve procedures (TVP) during continuous-flow left ventricular assist device (LVAD) implantation.
Methods: We retrospectively reviewed patients who received HeartMate II or 3 from 2004 to 2023. Nine patients who had a previous TVP were excluded.
Iron-Catalyzed Decarboxylative Sulfinylation of Alkyl Carboxylic Acids.
Org Lett
September 2025
Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, U.K.
Sulfinamides, sulfonamides, and sulfonimidamides are valuable motifs in medicinal chemistry, yet methods to synthesize alkyl variants from simple, readily available feedstocks remain scarce. In this report, we detail the synthesis of these three distinct sulfur functional groups, using readily available and structurally diverse alkyl carboxylic acids as the starting materials. The method harnesses alkyl radical generation from carboxylic acids using commercial iron salts and visible light irradiation, in combination with commercial sulfinylamine reagents, to deliver alkyl sulfinamide products.
View Article and Find Full Text PDFHydrocarbothermal flow synthesis of carbon-supported small and dense high-entropy alloy nanoparticles as electrocatalysts.
Nat Commun
September 2025
College of Chemistry and Chemical Engineering, Hunan University, Changsha, China.
Supported small and dense high-entropy-alloy nanoparticles (HEA-NPs) are promising functional materials for many applications. However, their synthesis remains a grand challenge because the extreme heating typically required to raise the entropic contribution to the formation of a solid solution unavoidably causes the sintering of HEA-NPs. Herein, we present a one-step continuous-flow spray pyrolysis strategy to synthesize multicomponent (from quinary to denary) HEA-NPs with an average size of <2 nanometers and metal loadings of ~30 wt% uniformly dispersed on various carbon substrates, including graphene and carbon black.
View Article and Find Full Text PDFA biophysical approach to studying N-terminal cysteine oxidase substrate preferences.
Methods Enzymol
August 2025
School of Chemistry, The University of Sydney, Sydney, NSW, Australia. Electronic address:
N-terminal cysteine oxidases (NCOs) regulate adaptive responses to hypoxia in animals and plants, functioning as enzymatic oxygen sensors which control the oxygen-dependant stability of proteins bearing an N-terminal cysteine residue (Nt-cys) through the N-degron pathway. However, the precise properties governing NCO activity and substrate selectivity remain poorly understood. This chapter details optimised protocols for investigating the binding interactions between 2-aminoethanethiol (cysteamine) dioxygenase (ADO), a mammalian NCO, and its Nt-cys substrates using surface plasmon resonance (SPR) spectroscopy.
View Article and Find Full Text PDFEnhanced enzyme stability at the interphase of water-oil for continuous-flow olefin epoxidation.
Nat Commun
August 2025
Engineering Research Center of Ministry of Education for Fine Chemicals, Shanxi Key Laboratory of Coal-based Value-added Chemicals Green Catalysis Synthesis, School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan, China.
The practical applications of enzymes often require their immobilization for multiple recycling or long-term running. However, practically efficient enzyme immobilization methods are lacking. Herein, we present an enzyme immobilization approach by engineering a porous "interphase" between water and oil around the surfaces of Pickering emulsion droplets.
View Article and Find Full Text PDF