Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201666 | PMC |
| http://dx.doi.org/10.1016/j.gendis.2022.08.022 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Polystyrene particles induces asthma-like Th2-mediated lung injury through IL-33 secretion.
Environ Int
September 2025
Center for Respiratory Safety Research, Korea Institute of Toxicology, 30 Baehak1-gil, Jeongeup, Jeollabuk-do 56212, Republic of Korea; Department of Human and Environmental Toxicology, University of Science & Technology, Daejeon 34113, Republic of Korea. Electronic address:
Plastics, particularly polystyrene (PS), are extensively used worldwide, especially in disposable packaging, which contributes to environmental pollution by generating microplastic particles. Herein, we investigated the pulmonary toxic effects of PS microplastics, focusing on airway inflammation and immune response. PS microplastic (50 nm to 1 μm) exposure was more likely to cause a severe pulmonary inflammatory response, particularly with smaller particle sizes.
View Article and Find Full Text PDFIdentification and Exploration of Novel B Cell Infiltration-Related Biomarkers in Endometriosis.
Am J Reprod Immunol
September 2025
Department of Laboratory Animal Science, Kunming Medical University, Kunming, China.
Objective: To explore B cell infiltration-related genes in endometriosis (EM) and investigate their potential as diagnostic biomarkers.
Methods: Gene expression data from the GSE51981 dataset, containing 77 endometriosis and 34 control samples, were analyzed to detect differentially expressed genes (DEGs). The xCell algorithm was applied to estimate the infiltration levels of 64 immune and stromal cell types, focusing on B cells and naive B cells.
Comparative analysis of colonization and survival strategies of regionally predominant LA-MRSA clones ST398 and ST9.
mSystems
September 2025
National Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Livestock-associated methicillin-resistant (LA-MRSA) displays distinct geographical distribution patterns, with ST398 predominating in Europe and ST9 being the dominant lineage in Asia, particularly China. However, the mechanisms underlying these differences remain poorly understood. In this study, we evaluated the cell adhesion capacity, anti-phagocytic properties, and porcine nasal colonization potential of ST9 and ST398 strains isolated from China and Germany.
View Article and Find Full Text PDFNr4a2, A Key Factor Controlling the Development and Functional Maintenance of Forebrain Car3 Neurons.
Neurosci Bull
September 2025
Laboratory Animal Center, Fudan University, Shanghai, 200032, China.
Nr4a2 (Nurr1) is well known to be vital for midbrain dopaminergic neurons. Recent single-cell RNA analyses reveal that Nr4a2 is expressed in lateral cerebral regions, within neurons named L4/L5/L6 IT Car3. These neurons have attracted intense attention for the molecular mechanisms underlying their development and functions.
View Article and Find Full Text PDFTgAP2X-7 is a novel cell cycle-regulated transcription factor that plays an essential role in tachyzoite propagation.
mSphere
September 2025
Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Blacksburg, Virginia, USA.
Apicomplexan AP2 (ApiAP2) family proteins are a family of transcription factors that are known to regulate gene expression in apicomplexan pathogens, including . In this study, we focused on TgAP2X-7, a member of the APiAP2 family that is predicted to be essential for fitness. Endogenous tagging of TgAP2X-7 followed by immunofluorescence analysis revealed that it's a cell cycle-regulated nuclear protein with peak expression in the G1 phase.
View Article and Find Full Text PDF