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Objective And Aims: To assess percutaneous vesselplasty's safety and efficacy in treating pathological vertebral compression fractures (VCFs).
Subjects And Methods: This retrospective review covered nine patients with an equal number of symptomatic pathological VCFs treated with vesselplasty. The study assessed the patients' pain scores, subjective conditions, imaging guidance, and incidence of procedure-related complications.
Results: The VCFs were at the T4 and L5 spine regions. The procedure success rate was 100%. In 88.89% (8/9) of the examined cases, there was a posterior vertebral body or pedicle involvement or both. Two patients with high thoracic VCFs underwent combined computed tomography and mobile C-arm fluoroscopy guidance. The other patients underwent digital subtraction angiography guidance. The average visual analog scale (VAS) score and the Oswestry Disability Index (ODI) before the treatment were 7.78 ± 0.67 standard deviation (SD) and 75.45 ± 7.55, respectively. The average VAS score and ODI 3 months after the treatment were 2.67 ± 0.50 (SD) and 32.45 ± 6.19 (P < 0.001), respectively. There were no recorded cases of symptomatic cement leakage or other operation-associated complications.
Conclusions: Percutaneous vesselplasty appears to be a safe and effective minimally invasive local treatment for pathological VCFs. This approach may offer benefits in improving pain, mobility, and function and minimizing the bone cement leakage rate while providing a safe and effective alternative treatment for pathological VCFs.
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http://dx.doi.org/10.4103/jcrt.jcrt_1349_21 | DOI Listing |
Spine (Phila Pa 1976)
June 2025
Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Study Design: This study employed a retrospective data analysis approach combined with model development and validation.
Objectives: The present study introduces a 2.5D convolutional neural network (CNN) model leveraging CT imaging to facilitate the early detection of malignant vertebral compression fractures (MVCFs), potentially reducing reliance on invasive biopsies.
Front Oncol
May 2025
Department of Radiology, Third Hospital of Hebei Medical University, Shijiangzhuang, China.
Objective: Vertebral compression fractures (VCFs) represent a prevalent clinical problem, yet distinguishing acute benign variants from malignant pathological fractures constitutes a persistent diagnostic dilemma. To develop and validate a MRI-based nomogram combining clinical and deep learning radiomics (DLR) signatures for the differentiation of benign versus malignant vertebral compression fractures (VCFs).
Methods: A retrospective cohort study was conducted involving 234 VCF patients, randomly allocated to training and testing sets at a 7:3 ratio.
Radiother Oncol
July 2025
Department of Radiation Oncology, University Hospital Zurich, Zurich, Switzerland.
Purpose: To prospectively evaluate safety and efficacy of dose-intensified multifraction SBRT using a simultaneous-integrated boost concept for vertebral oligometastases.
Material And Methods: Data from 128 patients with 143 vertebral oligometastases (≤5 distant metastases in total) treated with dose-intensified SBRT (48.5 Gy/10 [with epidural involvement] or 40 Gy/5 [without epidural involvement]) in the randomized and non-randomized arms of a phase 3 clinical trial conducted at 18 international centers between 2016 and 2023 were analyzed.
J Clin Med
April 2025
Department of Pain Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 01605, USA.
Percutaneous vertebral augmentation techniques, including vertebroplasty, kyphoplasty, and bone tumor radiofrequency ablation (BT-RFA), are commonly used to treat painful vertebral compression fractures (VCFs). While generally safe and effective, they carry risks, including cement extravasation, which can lead to pulmonary embolism or spinal cord compression. This study aims to compare the rate of cement extravasation across different vertebral augmentation techniques and identify potential risk factors.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
May 2025
Department of Neuroradiology, Ludwig Maximilians University Hospital, Ludwig Maximilians University (LMU) Munich, Munich, Germany.
Objective: Chemical shift encoded-based water-fat separation magnetic resonance imaging (CSE-MRI) is an emerging noninvasive tool for the assessment of bone and muscle composition. This study aims to examine both the predictive value and the longitudinal change of proton density fat fraction (PDFF) and T2* in the paraspinal muscles (PSM) in patients with and without the development of an incidental vertebral compression fracture (VCFs) after 6 months of follow-up.
Methods: Patients (N=56) with CT and 3T CSE-MRI of the lumbar spine at baseline and CSE-MRI at 6 months follow-up were included in this retrospective study.